Independent Human MAP-Kinase Signal Transduction Pathways Defined by MEK and MKK Isoforms

Dérijard, Benoit, Raingeaud, Joël, Barrett, Tamera, Wu, I-Huan, Han, Jiahuai, Ulevitch, Richard J., Davis, Roger J.·1995·Science

DOI 10.1126/science.7839144

Cited by (1,001)

Items 501–600 of 1,001

Cloning and Characterization of a Human STE20-like Protein Kinase with Unusual Cofactor Requirements
Karin A. Schinkmann, John Blenis · 1997 · Journal of Biological Chemistry
SEK1/MKK4-Mediated SAPK/JNK Signaling Participates in Embryonic Hepatoblast Proliferation via a Pathway Different from NF-κB-Induced Anti-Apoptosis
Tomomi Watanabe‐Asaka, Kentaro Nakagawa, Shinya Ohata, Daiju Kitagawa, Gen Nishitai, Jungwon Seo, Shuhei Tanemura, Nao Shimizu, Hiroyuki Kishimoto, Teiji Wada et al. · 2002 · Developmental Biology
Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells
A Nehmé, Rathinasamy Baskaran, S Nebel, Daniel A. Fink, Stephen B. Howell, J Y J Wang, Randolph D. Christen · 1999 · British Journal of Cancer
Protein kinase Cθ, a selective upstream regulator of JNK/SAPK and IL-2 promoter activation in Jurkat T cells
Nassim Ghaffari‐Tabrizi‐Wizsy, Birgit Bauer, Andreas Villunger, Gabriele Baier-Bitterlich, Amnon Altman, Gerd Utermann, Florian Überall, Gottfried Baier · 1999 · European Journal of Immunology
JunB Forms the Majority of the AP-1 Complex and Is a Target for Redox Regulation by Receptor Tyrosine Kinase and G Protein-coupled Receptor Agonists in Smooth Muscle Cells
Gadiparthi N. Rao, Khurshed A. Katki, Nageswara R. Madamanchi, Yaxu Wu, Michael J. Birrer · 1999 · Journal of Biological Chemistry
Tumor Necrosis Factor-α Activation of the c-Jun N-terminal Kinase Pathway in Human Neutrophils
Natalie J. Briones, Jerry A. Nick, Ben B. Whitlock, Marcella A. Billstrom, Peter M. Henson, Gary L. Johnson, G. Scott Worthen · 2001 · Journal of Biological Chemistry
Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-activating Polypeptide Inhibit Nuclear Factor-κB-dependent Gene Activation at Multiple Levels in the Human Monocytic Cell Line THP-1
Mario Delgado, Doina Ganea · 2001 · Journal of Biological Chemistry
A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type‐D GABAergic motor neurons
Masato Kawasaki, Naoki Hisamoto, Yuichi Iino, Masayuki P. Yamamoto, Jun Ninomiya‐Tsuji, Kunihiro Matsumoto · 1999 · The EMBO Journal
The Mitogen-activated Protein (MAP) Kinase p38 and Its Upstream Activator MAP Kinase Kinase 6 Are Involved in the Activation of Signal Transducer and Activator of Transcription by Hyperosmolarity*
J. Bode, Petros Gatsios, S. Ludwig, U. Rapp, D. Häussinger, P. Heinrich, L. Graeve · 1999 · Journal of Biological Chemistry
Ras-MAP Kinase Signaling Pathways and Control of Cell Proliferation: Relevance to Cancer Therapy
Paul S. Shapiro · 2002 · Critical Reviews in Clinical Laboratory Sciences
The Evi‐1 oncoprotein inhibits c‐Jun N‐terminal kinase and prevents stress‐induced cell death
Mineo Kurokawa, Kinuko Mitani, Tetsuya Yamagata, Tokiharu Takahashi, Koji Izutsu, Seishi Ogawa, Tetsuo Moriguchi, Eisuke Nishida, Yoshio Yazaki, Hisamaru Hirai · 2000 · The EMBO Journal
Cooperation of p38 and Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase Pathways during Granulocyte Colony-stimulating Factor-induced Hemopoietic Cell Proliferation
Oliver Rausch, Christopher J. Marshall · 1999 · Journal of Biological Chemistry
Stimulation of Stress-activated Protein Kinase and p38 HOG1 Kinase in Murine Keratinocytes following Photodynamic Therapy with Benzoporphyrin Derivative
Jing-Song Tao, Jasbinder Singh Sanghera, Steven Pelech, Geraldine Wong, Julia Gerwing Levy · 1996 · Journal of Biological Chemistry
The p38 MAPK Components and Modulators as Biomarkers and Molecular Targets in Cancer
Laura García-Hernández, María Belén García‐Ortega, Gloria Ruiz-Alcalá, Esmeralda Carrillo, Juan Antonio Marchal, María Ángel García · 2021 · International Journal of Molecular Sciences
Evidence of MKK4 pro-oncogenic activity in breast and pancreatic tumors
Lei Wang, Yong Pan, Jia Le Dai · 2004 · Oncogene
Stimulation of Elk1 Transcriptional Activity by Mitogen-activated Protein Kinases Is Negatively Regulated by Protein Phosphatase 2B (Calcineurin)
Jianmin Tian, Michael Karin · 1999 · Journal of Biological Chemistry
The Cell Cycle-Regulatory CDC25A Phosphatase Inhibits Apoptosis Signal-Regulating Kinase 1
Xianghong Zou, Tateki Tsutsui, Dipankar Ray, James F. Blomquist, Hidenori Ichijo, David S. Ucker, Hiroaki Kiyokawa · 2001 · Molecular and Cellular Biology
A temporal and biochemical link between growth factor-activated MAP kinases, cyclin D1 induction and cell cycle entry
Josée N. Lavoie, Nathalie Rivard, Gilles L’Allemain, Jacques Pouysségur · 1996 · Springer eBooks
A Novel Specific Role for IκB Kinase Complex-associated Protein in Cytosolic Stress Signaling
Christian Holmberg, Sigal Katz, Mads Lerdrup, Thomas Herdegen, Marja Jäättelä, Ami Aronheim, Tuula Kallunki · 2002 · Journal of Biological Chemistry
Marathon running transiently increases c‐Jun NH2‐terminal kinase and p38γ activities in human skeletal muscle
Marni D. Boppart, Sven Asp, Jørgen F. P. Wojtaszewski, Roger A. Fielding, Thomas T. Mohr, Laurie J. Goodyear · 2000 · The Journal of Physiology
Mitogen-activated protein kinases and nuclear factor-κB regulate Helicobacter pylori-mediated interleukin-8 release from macrophages
Asima Bhattacharyya, Shresh Pathak, Simanti Datta, Santanu Chattopadhyay, Joyoti Basu, Manikuntala Kundu · 2002 · Biochemical Journal
Differential Activation of p38 Mitogen-activated Protein Kinase and Extracellular Signal-regulated Protein Kinases Confers Cadmium-induced HSP70 Expression in 9L Rat Brain Tumor Cells
Jan‐Jong Hung, Ting-Jen Rachel Cheng, Yiu‐Kay Lai, Margaret Dah‐Tsyr Chang · 1998 · Journal of Biological Chemistry
Molecular Cloning and Characterization of Human JNKK2, a Novel Jun NH2-Terminal Kinase-Specific Kinase
Zhenguo Wu, Jun Wu, Estela Jacinto, Michael Karin · 1997 · Molecular and Cellular Biology
Elevated gadd153/chop expression and enhanced c-Jun N-terminal protein kinase activation sensitizes aged cells to ER stress
Ji Li, Nikki J. Holbrook · 2004 · Experimental Gerontology
Inhibition of p38 MAP Kinase Activity Up-Regulates Multiple MAP Kinase Pathways and Potentiates 1,25-Dihydroxyvitamin D3-Induced Differentiation of Human Leukemia HL60 Cells
Xuening Wang, Jie Rao, George P. Studzinski · 2000 · Experimental Cell Research
Differential Activation of p38 Mitogen-activated Protein Kinase Isoforms Depending on Signal Strength
Gema Alonso, Concetta Ambrosino, Margaret Jones, Ángel R. Nebreda · 2000 · Journal of Biological Chemistry
Molecular Cloning and Characterization of aDrosophila p38 Mitogen-activated Protein Kinase
Sung Jun Han, Kang Yell Choi, Paul T. Brey, Won‐Jae Lee · 1998 · Journal of Biological Chemistry
Poly(ADP-Ribose) Polymerase-1 Regulates Activation of Activator Protein-1 in Murine Fibroblasts
Teresa L. Andreone, Michael P O’Connor, Alvin G. Denenberg, Paul W. Hake, Basilia Zingarelli · 2003 · The Journal of Immunology
Silencing of the JNK pathway maintains progesterone receptor activity in decidualizing human endometrial stromal cells exposed to oxidative stress signals
Beatriz Leitao, Marius C. Jones, Luca Fusi, JENNY M. HIGHAM, Yun Jung Lee, Masashi Takano, Tomoko Gotō, Mark Christian, Eric W.‐F. Lam, Jan Joris Brosens · 2009 · The FASEB Journal
Selective suppression of stress‐activated protein kinase pathway by protein phosphatase 2C in mammalian cells
Masahito Hanada, Takayasu Kobayashi, Motoko Ohnishi, Shoko Ikeda, Hong Wang, Koji Katsura, Yuchio Yanagawa, Akira Hiraga, Ryunosuke Kanamaru, Shinri Tamura · 1998 · FEBS Letters
Jun Kinases Are Rapidly Activated by Cholecystokinin in Rat Pancreas both in Vitro and in Vivo
A Dâbrowski, Terrence Grady, Craig D. Logsdon, John A. Williams · 1996 · Journal of Biological Chemistry
Regulation of the Intracellular Localization of Foxo3a by Stress-Activated Protein Kinase Signaling Pathways in Skeletal Muscle Cells
Stéphan Clavel, Sandrine Siffroi‐Fernandez, Anne-Sophie Coldefy, Kim E. Boulukos, Didier F. Pisani, Benoı̂t Dérijard · 2009 · Molecular and Cellular Biology
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines
James Campbell, Colm J. Ryan, Rachel Brough, Ilirjana Bajrami, Helen N. Pemberton, Irene Yu-Shing Chong, Sara Costa-Cabral, Jessica R. Frankum, Aditi Gulati, Harriet Holme et al. · 2016 · Cell Reports
Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development
Hongbo Chi, Matthew R. Sarkisian, PASKO T. RAKIC, Richard Anthony Flavell · 2005 · Proceedings of the National Academy of Sciences
Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS
Pietro Veglianese, Daniele Lo Coco, Meritxell B. Cutrona, R. Magnoni, Danilo Pennacchini, B. Pozzi, Genevíève Gowing, Jean‐Pierre Julien, Massimo Tortarolo, Caterina Bendotti · 2005 · Molecular and Cellular Neuroscience
Co-stimulation-dependent activation of a JNK-kinase in T lymphocytes
Ayelet Avraham, Steffen Jung, Yardena Samuels, Rony Seger, Yinon Ben‐Neriah · 1998 · European Journal of Immunology
Epidermal Growth Factor Induction of the c- jun Promoter by a Rac Pathway
Nicole M Clarke, Natalia Arenzana, Tsonwin Hai, Audrey Minden, Ron Prywes · 1998 · Molecular and Cellular Biology
Mammalian Mitogen-activated Protein Kinase Pathways Are Regulated through Formation of Specific Kinase-Activator Complexes
Brent W. Zanke, Elizabeth A. Rubie, Elaine Winnett, Joanne Chung-Yan Chan, Susan Randall, Michael Parsons, Kim Boudreau, Mathew McInnis, Minhong Yan, Dennis J. Templeton et al. · 1996 · Journal of Biological Chemistry
The MAPK Pathway-Based Drug Therapeutic Targets in Pituitary Adenomas
Miaolong Lu, Wang Ya, Xianquan Zhan · 2019 · Frontiers in Endocrinology
Potential of p38-MAPK inhibitors in the treatment of ischaemic heart disease
James Clark, Negin Sarafraz, Michael S. Marber · 2007 · Pharmacology & Therapeutics
TGF-β1stimulates HO-1 via the p38 mitogen-activated protein kinase in A549 pulmonary epithelial cells
Wen Ning, Ruiping Song, Chaojun Li, Edward Park, Amir Mohsenin, Augustine M.K. Choi, Mary E. Choi · 2002 · American Journal of Physiology-Lung Cellular and Molecular Physiology
Cell Stress and MEKK1-mediated c-Jun Activation Modulate NFκB Activity and Cell Viability
Isabel Sánchez‐Pérez, Salvador Aznar Benitah, Montserrat Martínez-Gomáriz, Juan Carlos Lacal, Rosario Perona · 2002 · Molecular Biology of the Cell
The Differential Role of Extracellular Signal-Regulated Kinases and p38 Mitogen-Activated Protein Kinase in Eosinophil Functions
Tetsuya Adachi, Barun K. Choudhury, Susan J Stafford, Sanjiv A. Sur, Rafeul Alam · 2000 · The Journal of Immunology
Comparative Proteomes of the Proliferating C2C12 Myoblasts and Fully Differentiated Myotubes Reveal the Complexity of the Skeletal Muscle Differentiation Program
Nilesh S. Tannu, Vamshi K. Rao, Ritcha M. Chaudhary, Francesco Giorgianni, Abdelwahab E. Saeed, Yong Gao, Rajendra Raghow · 2004 · Molecular & Cellular Proteomics
Activation of p38 Mitogen-Activated Protein Kinase In Vivo Selectively Induces Apoptosis of CD8 + but Not CD4 + T Cells
Chris Merritt, Hervé Enslen, Nicole L. Diehl, Dietrich B. Conze, Roger J. Davis, Mercedes Rincón · 2000 · Molecular and Cellular Biology
RAC1/P38 MAPK Signaling Pathway Controls β1 Integrin–Induced Interleukin-8 Production in Human Natural Killer Cells
Fabrizio Mainiero, Alessandra Soriani, Raffaele Strippoli, Jordan Jacobelli, Angela Gismondi, Mario Piccoli, Luigi Frati, Angela Santoni · 2000 · Immunity
Role of the Mitogen-Activated Protein Kinases in the Expression of the Kinin B1 Receptors Induced by Tissue Injury
Jean‐François Larrivée, Dimcho R Bachvarov, François Houle, Jacques Landry, Jacques Huot, François Marceau · 1998 · The Journal of Immunology
Activation of the HIV-1 Long Terminal Repeat by Cytokines and Environmental Stress Requires an Active CSBP/p38 MAP Kinase
Sanjay Kumar, Michael J. Orsini, John C. Lee, Peter McDonnell, Christine M. Debouck, Peter R. Young · 1996 · Journal of Biological Chemistry
Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer’s disease progression
Mercedes Lachén‐Montes, Andrea González-Morales, María Victoria Zelaya, Estela Pérez‐Valderrama, Karina Ausín, Isidró Ferrer, Joaquín Fernández‐Irigoyen, Enrique Santamaría · 2017 · Scientific Reports
2 Discovery of Cep-1347/Kt-7515, an Inhibitor of the Jnk/Sapk Pathway for the Treatment of Neurodegenerative Diseases
Michael S. Saporito, Robert L. Hudkins, Anna Coco Maroney · 2002 · Progress in medicinal chemistry
MEKK1 interacts with ?-actinin and localizes to stress fibers and focal adhesions
Lori B. Christerson, Colleen A. Vanderbilt, Melanie H. Cobb · 1999 · Cell Motility and the Cytoskeleton
p38α MAPK inhibits JNK activation and collaborates with IκB kinase 2 to prevent endotoxin‐induced liver failure
Jan Heinrichsdorff, Tom Luedde, Eusebio Perdiguero, Ángel R. Nebreda, Manolis Pasparakis · 2008 · EMBO Reports
Naturally Occurring Neomorphic PIK3R1 Mutations Activate the MAPK Pathway, Dictating Therapeutic Response to MAPK Pathway Inhibitors
Lydia W.T. Cheung, Shuangxing Yu, Dong Zhang, Jie Li, Patrick Kwok‐Shing Ng, Nattapon Panupinthu, Shreya Mitra, Zhenlin Ju, Qinghua Yu, Han Liang et al. · 2014 · Cancer Cell
Murine p38-δ Mitogen-activated Protein Kinase, a Developmentally Regulated Protein Kinase That Is Activated by Stress and Proinflammatory Cytokines
Mickey C.‐T. Hu, Youping Wang, Adel A. Mikhail, Wan Rong Qiu, Tse‐Hua Tan · 1999 · Journal of Biological Chemistry
Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components
Jan Jacob Schuringa, Luigi J.C. Jonk, Wim H.A. Dokter, Edo Vellenga, Wiebe Kruijer · 2000 · Biochemical Journal
The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells.
Francis Dodeller, Hendrik Schulze‐Koops · 2006 · Arthritis Research & Therapy
Human Mitogen-activated Protein Kinase Kinase 7 (MKK7) Is a Highly Conserved c-Jun N-terminal Kinase/Stress-activated Protein Kinase (JNK/SAPK) Activated by Environmental Stresses and Physiological Stimuli
Ian N. Foltz, Robert E. Gerl, James S. Wieler, Michael Luckach, Ruth A. Salmon, John W. Schrader · 1998 · Journal of Biological Chemistry
Amplifications of DNA primase 1 (PRIM1) in human osteosarcoma
Wagner V. Yotov, Hugo Hamel, George-Etienne Rivard, Martin A. Champagne, Pierre Russo, Jean‐Marie Leclerc, Mark L. Bernstein, Emile H. Levy · 1999 · Genes Chromosomes and Cancer
The Death Domain Kinase RIP1 Is Essential for Tumor Necrosis Factor Alpha Signaling to p38 Mitogen-Activated Protein Kinase
Thomas H. Lee, Qiaojia Huang, Sarah Oikemus, Jennifer Shank, Juan‐José Ventura, Nicole Cusson, Richard R. Vaillancourt, Bing Su, Roger J. Davis, Michelle A. Kelliher · 2003 · Molecular and Cellular Biology
Regulation of Stat3 Activation by MEK Kinase 1
Cheh Peng Lim, Xinmin Cao · 2001 · Journal of Biological Chemistry
AMPK Regulates Metabolic Actions of Glucocorticoids by Phosphorylating the Glucocorticoid Receptor through p38 MAPK
Nancy Nader, Sinnie Sin Man Ng, George Ι. Lambrou, Panagiota Pervanidou, Yonghong Wang, George Panagiotis Chrousos, Tomoshige Kino · 2010 · Molecular Endocrinology
Activation of the p38 Mitogen-Activated Protein Kinase Pathway Arrests Cell Cycle Progression and Differentiation of Immature Thymocytes in Vivo
Nicole L. Diehl, Hervé Enslen, Karen A. Fortner, Chris Merritt, Nate Stetson, Colette Charland, Richard Anthony Flavell, Roger J. Davis, Mercedes Rincón · 2000 · The Journal of Experimental Medicine
Activation of Stress-activated Protein Kinases/c-Jun N-terminal Protein Kinases (SAPKs/JNKs) by a Novel Mitogen-activated Protein Kinase Kinase (MKK7)
Zhengbin Yao, Katrina Diener, Xuhong Sunny Wang, Mark M. Zukowski, Goichi Matsumoto, Guisheng Zhou, Rong Mo, Takehiko Sasaki, Hiroshi Nishina, Chi-chung Hui et al. · 1997 · Journal of Biological Chemistry
TNF-α-induced Regulation and Signalling in Macrophages
David W. H. Riches, Edward D. Chan, Brent W. Winston · 1996 · Immunobiology
Brx Mediates the Response of Lymphocytes to Osmotic Stress Through the Activation of NFAT5
Tomoshige Kino, Hiroaki Takatori, Irini Manoli, Yonghong Wang, Anatoly Nikolaevich Tiulpakov, Marc R. Blackman, Yan A. Su, George Panagiotis Chrousos, Alan H. DeCherney, James H. Segars · 2009 · Science Signaling
Regulation of C2C12 myogenic terminal differentiation by MKK3/p38α pathway
Candice Cabane, Walter Englaro, Karen Yeow, Michel Ragno, Benoı̂t Dérijard · 2003 · American Journal of Physiology-Cell Physiology
Apoptosis and cancer chemotherapy
Guy Makin, Caroline Dive · 2001 · Trends in Cell Biology
Activation of the p38 Mitogen-activated Protein Kinase Pathway by Estrogen or by 4-Hydroxytamoxifen Is Coupled to Estrogen Receptor-induced Apoptosis
Cheng Cheng Zhang, David J. Shapiro · 2000 · Journal of Biological Chemistry
p120 GAP Modulates Ras Activation of Jun Kinases and Transformation
Geoffrey J. Clark, John K. Westwick, Channing J. Der · 1997 · Journal of Biological Chemistry
Lack of c‐Jun activity increases survival to cisplatin
Isabel Sánchez‐Pérez, Rosario Perona · 1999 · FEBS Letters
CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency.
Pamela Sarah Cohen, Harikrishna Nakshatri, Jameel Dennis, Theresa A. Caragine, M Bianchi, Anthony Cerami, Kevin J. Tracey · 1996 · Proceedings of the National Academy of Sciences
Oxidative Stress Induces Reactivation of Kaposi's Sarcoma-Associated Herpesvirus and Death of Primary Effusion Lymphoma Cells
Xudong Li, Jiaying Feng, Ren Sun · 2010 · Journal of Virology
Requirement of Mitogen-activated Protein Kinase Kinase 3 (MKK3) for Activation of p38α and p38δ MAPK Isoforms by TGF-β1 in Murine Mesangial Cells
Lin Wang, Rui Ma, Richard Anthony Flavell, Mary E. Choi · 2002 · Journal of Biological Chemistry
Specific Activation of a c-Jun NH2-terminal Kinase Isoform and Induction of Neurite Outgrowth in PC-12 Cells by Staurosporine
Ryoji Yao, Maki Yoshihara, Hiroyuki Osada · 1997 · Journal of Biological Chemistry
Regulation of c-Jun NH2-terminal Kinase ( Jnk) Gene Expression during T Cell Activation
Linda Weiss, Alan J. Whitmarsh, Derek D. Yang, Mercedes Rincón, Roger J. Davis, Richard Anthony Flavell · 2000 · The Journal of Experimental Medicine
The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors
Caroline Weinstein Oppenheimer, William L. Blalock, Linda S. Steelman, Fumin Chang, James Andrew McCubrey · 2000 · Pharmacology & Therapeutics
Mirk/dyrk1B Is a Rho-induced Kinase Active in Skeletal Muscle Differentiation
Xiaobing Deng, Daina Z. Ewton, Bradley T. Pawlikowski, Margaret M. Maimone, Eileen Friedman · 2003 · Journal of Biological Chemistry
Eccentric exercise markedly increases c-Jun NH 2 -terminal kinase activity in human skeletal muscle
Marni D. Boppart, Doron Aronson, Lindsay Gibson, Ronenn Roubenoff, Leslie W. Abad, Jonathan F. Bean, Laurie J. Goodyear, Roger A. Fielding · 1999 · Journal of Applied Physiology
MEK Kinase 3 Directly Activates MKK6 and MKK7, Specific Activators of the p38 and c-Jun NH2-terminal Kinases
Karl Deacon, Jonathan L. Blank · 1999 · Journal of Biological Chemistry
Nuclear Factor-κB Activation by the CXC Chemokine Melanoma Growth-stimulatory Activity/Growth-regulated Protein Involves the MEKK1/p38 Mitogen-activated Protein Kinase Pathway
Dingzhi Wang, Ann Richmond · 2001 · Journal of Biological Chemistry
Study of Proline-Directed Protein Kinases Involved in Phosphorylation of the Heavy Neurofilament Subunit
Benoit I. Giasson, Walter E. Mushynski · 1997 · Journal of Neuroscience
JNK Activation Is Required for JB6 Cell Transformation Induced by Tumor Necrosis Factor-α but Not by 12-O-Tetradecanoylphorbol-13-Acetate
Chuanshu Huang, Jingxia Li, Weiya Ma, Zigang Dong · 1999 · Journal of Biological Chemistry
Mutant p53-induced Up-regulation of Mitogen-activated Protein Kinase Kinase 3 Contributes to Gain of Function
Aymone Gurtner, Giuseppe Starace, Giuseppe Norelli, Giulia Piaggio, Ada Sacchi, Gianluca Bossi · 2010 · Journal of Biological Chemistry
Intracellular IL-1Ra type 1 inhibits IL-1-induced IL-6 and IL-8 production in Caco-2 intestinal epithelial cells through inhibition of p38 mitogen-activated protein kinase and NF-κB pathways
Chrystelle Garat · 2003 · Cytokine
Interleukin 1 (IL1) and tumour necrosis factor (TNF) signal transduction
Jeremy Saklatvala, W. Davis, François Guesdon, Christopher John Marshall · 1996 · Philosophical Transactions of the Royal Society B Biological Sciences
The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis
Marcel Verheij, Gerald A. Ruiter, Shuraila F. Zerp, Wim J. VAN BLITTERSWIJK, ZVI Y. FUKS, Adriana Haimovitz‐Friedman, Harry G M M Bartelink · 1998 · Radiotherapy and Oncology
Activation of MEK Kinase 1 by the c-Abl Protein Tyrosine Kinase in Response to DNA Damage
Surender M. Kharbanda, Pramod Pandey, Teruo Yamauchi, Shailender Kumar, Masao Kaneki, Vijay Kumar, Ajit K. Bharti, Zhi-Min Yuan, Louis R. Ghanem, Ajay Rana et al. · 2000 · Molecular and Cellular Biology
The activation of distinct mitogen-activated protein kinase cascades is required for the stimulation of 2-deoxyglucose uptake by interleukin-1 and insulin-like growth factor-1 in KB cells
Gwyn W. Gould, Ana Cuenda, FIONA J. THOMSON, Patricia T.W. Cohen · 1995 · Biochemical Journal
Multiple Activation Mechanisms of p38α Mitogen-activated Protein Kinase
Young Jun Kang, Alim S. Seit‐Nebi, Roger J. Davis, Jiahuai Han · 2006 · Journal of Biological Chemistry
Independent Role of p38 and ERK1/2 Mitogen-Activated Kinases in the Upregulation of Matrix Metalloproteinase-1
Maria A. Brauchle, Dorothea Glück, Franco Di Padova, Jiahuai Han, Hermann Gram · 2000 · Experimental Cell Research
Activation of stress-activated MAP protein kinases up-regulates expression of transgenes driven by the cytomegalovirus immediate/early promoter
Wendy Bruening, Benoit I. Giasson, Walter E. Mushynski, Heather D. Durham · 1998 · Nucleic Acids Research
Peroxisome Proliferator-activated Receptor γ-independent Activation of p38 MAPK by Thiazolidinediones Involves Calcium/Calmodulin-dependent Protein Kinase II and Protein Kinase R
Olivia Gardner, Chung‐Wai Shiau, Ching‐Shih Chen, Lee M. Graves · 2005 · Journal of Biological Chemistry
Stimulus-specific Requirements for MAP3 Kinases in Activating the JNK Pathway
Wei Chen, Michael A. White, Melanie H. Cobb · 2002 · Journal of Biological Chemistry
Suppression of Metastatic Colonization by the Context-Dependent Activation of the c-Jun NH2-Terminal Kinase Kinases JNKK1/MKK4 and MKK7
Donald J. Vander Griend, Masha Kocherginsky, Jonathan A. Hickson, Walter Michael Stadler, Anning Lin, Carrie W Rinker-Schaeffer · 2005 · Cancer Research
Lithium regulates PKC‐mediated intracellular cross‐talk and gene expression in the CNS in vivo
Guang Chen, Monica I. Masana, Husseini K. Manji · 2000 · Bipolar Disorders
Activation of p38 MAP Kinase Pathway by Erythropoietin and Interleukin-3
Yuka Nagata, Tetsuo Moriguchi, Eisuke Nishida, Kazuo Todokoro · 1997 · Blood
Inhibition of Tumor Necrosis Factor-induced p42/p44 Mitogen-Activated Protein Kinase Activation by Sodium Salicylate
Paul Schwenger, Edward Y. Skolnik, J Vilček · 1996 · Journal of Biological Chemistry
Exercise Stimulates c-Jun NH2Kinase Activity and c-Jun Transcriptional Activity in Human Skeletal Muscle
Doron Aronson, Marni D. Boppart, Scott D. Dufresne, Roger A. Fielding, Laurie J. Goodyear · 1998 · Biochemical and Biophysical Research Communications
p38-MAPK Induced Dephosphorylation of α-Tropomyosin Is Associated With Depression of Myocardial Sarcomeric Tension and ATPase Activity
Susan Vahebi, Asuka Ota, Manxiang Li, Chad M. Warren, Pieter P. de Tombe, Yibin Wang, Ross John Solaro · 2007 · Circulation Research
Mitotic Aberration Coupled With Centrosome Amplification Is Induced by Hepatitis B Virus X Oncoprotein via the Ras-Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase-Mitogen-Activated Protein Pathway
Chawon Yun, Hyeseon Cho, Su-Jeong Kim, Jae‐Ho Lee, Sun Yi Park, Gordon K. T. Chan, Hyeseong Cho · 2004 · Molecular Cancer Research