Independent Human MAP-Kinase Signal Transduction Pathways Defined by MEK and MKK Isoforms

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Items 101–200 of 1,001

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6. Activation of the novel stress‐activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases
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7. Interferon‐γ expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway
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11. Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual‐specificity phosphatase.
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12. A critical role of neural-specific JNK3 for ischemic apoptosis
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14. The role of MAPK signalling pathways in the response to endoplasmic reticulum stress
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15. A Role for p38MAPK/HSP27 Pathway in Smooth Muscle Cell Migration
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16. The Role of Mitogen-Activated Protein Kinase Pathways in Alzheimer’s Disease
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17. The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation.
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18. p38 Map Kinase Mediates Bax Translocation in Nitric Oxide–Induced Apoptosis in Neurons
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19. Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways
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20. Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia
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21. Defective IL‐12 production in mitogen‐activated protein (MAP) kinase kinase 3 (Mkk3)‐deficient mice
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22. Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH 2 -terminal kinase
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23. Sequential Activation of the MEK-Extracellular Signal-Regulated Kinase and MKK3/6-p38 Mitogen-Activated Protein Kinase Pathways Mediates Oncogenic <i>ras</i> -Induced Premature Senescence
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24. Caspase‐mediated activation and induction of apoptosis by the mammalian Ste20‐like kinase Mst1
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25. Early Activation of c-Jun N-terminal Kinase and p38 Kinase Regulate Cell Survival in Response to Tumor Necrosis Factor α
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26. REGULATION OF GENE EXPRESSION BY HYPERTONICITY
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27. Activation of stress‐activated protein kinase‐3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38)
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28. The Dual Specificity Mitogen-activated Protein Kinase Phosphatase-1 and -2 Are Induced by the p42/p44MAPK Cascade
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29. MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines
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31. MAP kinase pathways activated by stress: The p38 MAPK pathway
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32. Mechanisms of liver fibrosis
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33. Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor
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34. IFN-γ + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38mapkin a mouse macrophage cell line
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35. Age-related Decline in Mitogen-activated Protein Kinase Activity in Epidermal Growth Factor-stimulated Rat Hepatocytes
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36. p38 Mitogen-Activated Protein Kinase Inhibitors— Mechanisms and Therapeutic Potentials
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38. Tumor Necrosis Factor ä-Induced E-selectin Expression Is Activated by the Nuclear Factor-κB and c-JUN N-terminal Kinase/p38 Mitogen-activated Protein Kinase Pathways
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39. ATF-2 Is a Common Nuclear Target of Smad and TAK1 Pathways in Transforming Growth Factor-β Signaling
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40. Major pathways involved in macrophage polarization in cancer
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41. Identification of Mitogen-activated Protein (MAP) Kinase-activated Protein Kinase-3, a Novel Substrate of CSBP p38 MAP Kinase
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42. Signal Transduction Pathways Regulated by Mitogen-activated/Extracellular Response Kinase Kinase Kinase Induce Cell Death
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43. rac1 Regulates a Cytokine-Stimulated, Redox-Dependent Pathway Necessary for NF-κB Activation
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44. Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2
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45. The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c‐fos transcription in response to UV light.
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46. Ras-Mediated Phosphorylation of a Conserved Threonine Residue Enhances the Transactivation Activities of c-Ets1 and c-Ets2
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47. hemipterous encodes a novel drosophila MAP kinase kinase, required for epithelial cell sheet movement
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48. Molecular Cloning and Characterization of a Novel p38 Mitogen-activated Protein Kinase
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49. p38 mitogen-activated protein kinase activation is required for human neutrophil function triggered by TNF-alpha or FMLP stimulation.
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54. Differential Activation of Mitogen-activated Protein Kinases by Nitric Oxide-related Species
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55. Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3
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56. Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases
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57. Stress-activated Protein Kinases: Activation, Regulation and Function
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59. p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts
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60. MEKKs, GCKs, MLKs, PAKs, TAKs, and Tpls: upstream regulators of the c-Jun amino-terminal kinases?
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61. MLK‐3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6.
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62. A Role for the p38 Mitogen-activated Protein Kinase Pathway in Myocardial Cell Growth, Sarcomeric Organization, and Cardiac-specific Gene Expression
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63. Dopamine Induces Apoptosis through an Oxidation-involved SAPK/JNK Activation Pathway
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64. Analysis of ATF3, a Transcription Factor Induced by Physiological Stresses and Modulated by gadd153/Chop10
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65. Apoptosis and cancer chemotherapy
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66. Both Erk and p38 Kinases Are Necessary for Cytokine Gene Transcription
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67. Connective Tissue Growth Factor Gene Regulation
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73. YopJ of Yersinia pseudotuberculosis is required for the inhibition of macrophage TNF‐α production and downregulation of the MAP kinases p38 and JNK
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74. Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP.
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75. Raf: A Strategic Target for Therapeutic Development Against Cancer
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76. To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways
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77. Evidence for a Role of Rho-like GTPases and Stress-activated Protein Kinase/c-Jun N-terminal Kinase (SAPK/JNK) in Transforming Growth Factor β-mediated Signaling
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78. Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two‐component response regulator
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79. Motoneuron Apoptosis Is Blocked by CEP-1347 (KT 7515), a Novel Inhibitor of the JNK Signaling Pathway
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80. JNK Suppresses Apoptosis via Phosphorylation of the Proapoptotic Bcl-2 Family Protein BAD
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81. Fas Activation of the p38 Mitogen-Activated Protein Kinase Signalling Pathway Requires ICE/CED-3 Family Proteases
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82. Speed kills: cellular and molecular bases of methamphetamine‐induced nerve terminal degeneration and neuronal apoptosis
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83. Protein phosphatase 2Cα inhibits the human stress‐responsive p38 and JNK MAPK pathways
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84. Gab1 Acts as an Adapter Molecule Linking the Cytokine Receptor gp130 to ERK Mitogen-Activated Protein Kinase
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85. Apoptosis Induction by the Satratoxins and Other Trichothecene Mycotoxins: Relationship to ERK, p38 MAPK, and SAPK/JNK Activation
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86. Role of Mitogen-activated Protein Kinase Phosphatase during the Cellular Response to Genotoxic Stress
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87. p38 Mitogen-Activated Protein Kinase Activation Is Required for Human Neutrophil Function Triggered by TNF-α or FMLP Stimulation
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88. Role of the Jun Kinase Pathway in the Regulation of c-Jun Expression and Apoptosis in Sympathetic Neurons
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89. Selective activation and functional significance of p38α mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils
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90. JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway
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91. Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3
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92. Induction of Apoptosis by SB202190 through Inhibition of p38β Mitogen-activated Protein Kinase
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93. Reactive Oxygen Species and Antioxidants in Signal Transduction and Gene Expression
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94. The structure of mitogen-activated protein kinase p38 at 2.1-Å resolution
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95. Tumor necrosis factor α‐induced activation of c‐jun N‐terminal kinase is mediated by TRAF2
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96. MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration
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97. The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase
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98. Signal transduction events elicited by natural products: Role of MAPK and caspase pathways in homeostatic response and induction of apoptosis
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99. Diagnosis and Molecular Classification of Lung Cancer
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100. Actions of Rho Family Small G Proteins and p21-Activated Protein Kinases on Mitogen-Activated Protein Kinase Family Members
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