The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Direct Measurement of the Forces Between Complementary Strands of DNA
Abstract
Interaction forces between single strands of DNA were measured with the atomic force microscope by a procedure in which DNA oligonucleotides were covalently attached to a spherical probe and surface. Adhesive forces measured between complementary 20-base strands fell into three distinct distributions centered at 1.52, 1.11, and 0.83 nano-newtons, which are associated with the rupture of the interchain interaction between a single pair of molecules involving 20, 16, and 12 base pairs, respectively. When a third long DNA molecule was coupled between complementary surfaces, both intra- and interchain forces were observed. The intrachain interaction resulting from the molecule's elasticity manifested itself as a long-range cohesive force.
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Cites
Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid
WATSON, J. D., & CRICK, F. H. C. (1953) · Nature · doi:10.1038/171737a0 · Cited by 13,584
Theory of the elastic properties of rubber
James, H. M., & Guth, E. (1943) · The Journal of Chemical Physics · doi:10.1063/1.1723785 · Cited by 1,230
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Micromechanical cantilever-based biosensors
Raiteri, R., Grattarola, M., Butt, H.-J., & Skládal, P. (2001) · Sensors and Actuators B: Chemical · doi:10.1016/s0925-4005(01)00856-5 · Cited by 734
Jalili, N., & Laxminarayana, K. (2004) · Mechatronics · doi:10.1016/j.mechatronics.2004.04.005 · Cited by 610
Dynamic force spectroscopy of single DNA molecules
Strunz, T., Oroszlan, K., Schäfer, R., & Güntherodt, H.-J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.20.11277 · Cited by 580
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Probst, C. E., Zrazhevskiy, P., Bagalkot, V., & Gao, X. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.036 · Cited by 466
Metadata
- Authors
- Lee, G. U., Chrisey, L. A., & Colton, R. J.
- Venue
- Science
- Published
- 1994-11-04
- Volume
- 266
- Issue
- 5186
- Pages
- 771-773
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2056182522
- Cited by
- 764
- References
- 2
- FWCI
- 15.63
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lee, G. U., Chrisey, L. A., & Colton, R. J. (1994). Direct Measurement of the Forces Between Complementary Strands of DNA. Science. https://doi.org/10.1126/science.7973628
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
