The DOI matches its Crossref record.
Channel-Like Function of the Na,K Pump Probed at Microsecond Resolution in Giant Membrane Patches
Abstract
Ion transporters can be thought of as ion channels that open and close only at one end at a time. As in real channels, ions may cross through an electrical field as they diffuse into and bind within the transporter pore, thereby generating electrical current. Extracellular sodium binding by the sodium potassium (Na,K) pump is associated with ultrafast charge movements in giant cardiac membrane patches. The charge movements are complete within 4 microseconds. They occur only when binding sites are open to the extracellular side, and they are abolished by ouabain and by the removal of extracellular sodium. Fast extracellular ion binding may be the exclusive source of Na,K pump electrogenicity.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Signaling Mechanisms Underlying the Vascular Myogenic Response
Davis, M. J., & Hill, M. A. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.2.387 · Cited by 992
Cochlear Outer Hair Cell Motility
Ashmore, J. (2008) · Physiological Reviews · doi:10.1152/physrev.00044.2006 · Cited by 503
Aptamers selected for higher-affinity binding are not more specific for the target ligand
Carothers, J. M., Oestreich, S. C., & Szostak, J. W. (2006) · Journal of the American Chemical Society · doi:10.1021/ja060952q · Cited by 132
Metadata
- Authors
- Hilgemann, D. W.
- Venue
- Science
- Published
- 1994-03-11
- Volume
- 263
- Issue
- 5152
- Pages
- 1429-1432
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1994349958
- Cited by
- 198
- References
- 0
- FWCI
- 6.37
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Channel-Like Function of the Na,K Pump Probed at Microsecond Resolution in Giant Membrane Patches. https://app.cochat.ai/papers/10.1126/science.8128223
- The paper
- Hilgemann, D. W. (1994). Channel-Like Function of the Na,K Pump Probed at Microsecond Resolution in Giant Membrane Patches. Science. https://doi.org/10.1126/science.8128223
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
