The DOI matches its Crossref record.
Loss of Circadian Behavioral Rhythms and per RNA Oscillations in the Drosophila Mutant timeless
Abstract
Eclosion, or emergence of adult flies from the pupa, and locomotor activity of adults occur rhythmically in Drosophila melanogaster , with a circadian period of about 24 hours. Here, a clock mutation, timeless ( tim ), is described that produces arrhythmia for both behaviors. The effects of tim on behavioral rhythms are likely to involve products of the X chromosome-linked clock gene period ( per ), because tim alters circadian oscillations of per RNA. Genetic mapping places tim on the left arm of the second chromosome between dumpy ( dp ) and decapentaplegic ( dpp ).
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Lin, L., Faraco, J., Li, R., Kadotani, H., Rogers, W., Lin, X., Qiu, X., de Jong, P. J., Nishino, S., & Mignot, E. (1999) · Cell · doi:10.1016/s0092-8674(00)81965-0 · Cited by 2,613
Mop3 is an essential component of the master circadian pacemaker in mammals.
Bunger, M. K., Wilsbacher, L. D., Moran, S. M., Clendenin, C., Radcliffe, L. A., Hogenesch, J. B., Simon, M. C., Takahashi, J. S., & Bradfield, C. A. (2000) · Cell · doi:10.1016/s0092-8674(00)00205-1 · Cited by 1,621
Molecular mechanisms and physiological importance of circadian rhythms
Patke, A., Young, M. W., & Axelrod, S. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0179-2 · Cited by 1,388
Self-citationEmery, P., So, W. V., Kaneko, M., Hall, J. C., & Rosbash, M. (1998) · Cell · doi:10.1016/s0092-8674(00)81637-2 · Cited by 912
A Differential Response of Two Putative Mammalian Circadian Regulators, mper1and mper2, to Light
Albrecht, U., Sun, Z. S., Eichele, G., & Lee, C. C. (1997) · Cell · doi:10.1016/s0092-8674(00)80495-x · Cited by 879
Metadata
- Authors
- Sehgal, A., Price, J. L., Man, B., & Young, M. W.
- Venue
- Science
- Published
- 1994-03-18
- Volume
- 263
- Issue
- 5153
- Pages
- 1603-1606
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1992749367
- Cited by
- 651
- References
- 0
- FWCI
- 18.28
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Loss of Circadian Behavioral Rhythms and per RNA Oscillations in the Drosophila Mutant timeless. https://app.cochat.ai/papers/10.1126/science.8128246
- The paper
- Sehgal, A., Price, J. L., Man, B., & Young, M. W. (1994). Loss of Circadian Behavioral Rhythms and per RNA Oscillations in the Drosophila Mutant timeless. Science. https://doi.org/10.1126/science.8128246
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
