The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Genetic Animal Models of Alcohol and Drug Abuse
Abstract
Behavioral and pharmacological responses of selectively bred and inbred rodent lines have been analyzed to elucidate many features of drug sensitivity and the adverse effects of drugs, the underlying mechanisms of drug tolerance and dependence, and the motivational states underlying drug reward and aversion. Genetic mapping of quantitative trait loci (QTLs) has been used to identify provisional chromosomal locations of genes influencing such pharmacological responses. Recent advances in transgenic technology, representational difference analysis, and other molecular methods now make feasible the positional cloning of QTLs that influence sensitivity to drugs of abuse. This marks a new period of synthesis in pharmacogenetic research, in which networks of drug-related behaviors, their underlying pharmacological, physiological, and biochemical mechanisms, and particular genomic regions of interest are being identified.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Drugs of abuse: anatomy, pharmacology and function of reward pathways
Koob, G. F. (1992) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(92)90060-j · Cited by 2,070
Haley, C. S., & Knott, S. A. (1992) · Heredity · doi:10.1038/hdy.1992.131 · Cited by 1,991
The Dopamine D2 Receptor Locus as a Modifying Gene in Neuropsychiatric Disorders
Comings, D. E. (1991) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1991.03470130073032 · Cited by 587
Cited by
Genetic Dissection of Complex Traits
Lander, E. S., & Schork, N. J. (1994) · Science · doi:10.1126/science.8091226 · Cited by 3,413
Molecular and Cellular Basis of Addiction
Nestler, E. J., & Aghajanian, G. K. (1997) · Science · doi:10.1126/science.278.5335.58 · Cited by 1,313
Adverse Childhood Experiences and Smoking During Adolescence and Adulthood
Anda, R. F. (1999) · JAMA · doi:10.1001/jama.282.17.1652 · Cited by 1,256
Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice
Rhodes, J. S., Best, K., Belknap, J. K., Finn, D. A., & Crabbe, J. C. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2004.10.007 · Cited by 820
Self-citationTsuang, M. T., Lyons, M. J., Meyer, J. M., Doyle, T., Eisen, S. A., Goldberg, J., True, W., Lin, N., Toomey, R., & Eaves, L. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.11.967 · Cited by 710
Metadata
- Authors
- Crabbe, J. C., Belknap, J. K., & Buck, K. J.
- Venue
- Science
- Published
- 1994-06-17
- Volume
- 264
- Issue
- 5166
- Pages
- 1715-1723
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2072176522
- Cited by
- 418
- References
- 3
- FWCI
- 14.71
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Genetic Animal Models of Alcohol and Drug Abuse. https://app.cochat.ai/papers/10.1126/science.8209252
- The paper
- Crabbe, J. C., Belknap, J. K., & Buck, K. J. (1994). Genetic Animal Models of Alcohol and Drug Abuse. Science. https://doi.org/10.1126/science.8209252
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
