The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Ordered Restriction Maps of Saccharomyces cerevisiae Chromosomes Constructed by Optical Mapping
Abstract
A light microscope-based technique for rapidly constructing ordered physical maps of chromosomes has been developed. Restriction enzyme digestion of elongated individual DNA molecules (about 0.2 to 1.0 megabases in size) was imaged by fluorescence microscopy after fixation in agarose gel. The size of the resulting individual restriction fragments was determined by relative fluorescence intensity and apparent molecular contour length. Ordered restriction maps were then created from genomic DNA without reliance on cloned or amplified sequences for hybridization or analytical gel electrophoresis. Initial application of optical mapping is described for Saccharomyces cerevisiae chromosomes.
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Cites
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Coming of age: ten years of next-generation sequencing technologies
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Opportunities and challenges in long-read sequencing data analysis
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Alkan, C., Coe, B. P., & Eichler, E. E. (2011) · Nature Reviews Genetics · doi:10.1038/nrg2958 · Cited by 1,630
Chromosome-scale scaffolding of de novo genome assemblies based on chromatin interactions
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Assembling large genomes with single-molecule sequencing and locality-sensitive hashing
Berlin, K., Koren, S., Chin, C.-S., Drake, J. P., Landolin, J. M., & Phillippy, A. M. (2015) · Nature Biotechnology · doi:10.1038/nbt.3238 · Cited by 934
Metadata
- Authors
- Schwartz, D. C., Li, X., Hernandez, L. I., Ramnarain, S. P., Huff, E. J., & Wang, Y.-K.
- Venue
- Science
- Published
- 1993-10
- Volume
- 262
- Issue
- 5130
- Pages
- 110-114
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2065587065
- Cited by
- 411
- References
- 11
- FWCI
- 3.24
- Type
- journal article
- Language
- en
- Open access
- closed
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- Schwartz, D. C., Li, X., Hernandez, L. I., Ramnarain, S. P., Huff, E. J., & Wang, Y.-K. (1993). Ordered Restriction Maps of Saccharomyces cerevisiae Chromosomes Constructed by Optical Mapping. Science. https://doi.org/10.1126/science.8211116
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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