The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Sequence-Specific Binding of Transfer RNA by Glyceraldehyde-3-Phosphate Dehydrogenase
Abstract
A transfer RNA (tRNA) binding protein present in HeLa cell nuclear extracts was purified and identified as the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH). Studies with mutant tRNAs indicated that GAPDH recognizes both sequence and structural features in the RNA. GAPDH discriminated between wild-type tRNA and two tRNA mutants that are defective in nuclear export, which suggests that the protein may participate in RNA export. The cofactor nicotinamide adenine dinucleotide disrupted complex formation between tRNA and GAPDH and thus may share a common binding site with the RNA. Indirect immunofluorescence experiments showed that GAPDH is present in the nucleus as well as in the cytoplasm.
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Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm
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Cloning and domain structure of the mammalian splicing factor U2AF
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Cited by
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
Chang, C.-H., Curtis, J. D., Maggi, L. B., Faubert, B., Villarino, A. V., O’Sullivan, D., Huang, S. C.-C., van der Windt, G. J. W., Blagih, J., Qiu, J., et al. (2013) · Cell · doi:10.1016/j.cell.2013.05.016 · Cited by 2,204
Housekeeping genes as internal standards: use and limits
Thellin, O., Zorzi, W., Lakaye, B., De Borman, B., Coumans, B., Hennen, G., Grisar, T., Igout, A., & Heinen, E. (1999) · Journal of Biotechnology · doi:10.1016/s0168-1656(99)00163-7 · Cited by 1,544
mRNA stability in mammalian cells
Ross, J. (1995) · Microbiological Reviews · doi:10.1128/mr.59.3.423-450.1995 · Cited by 1,411
Teusink, B., Passarge, J., Reijenga, C. A., Esgalhado, E., van der Weijden, C. C., Schepper, M., Walsh, M. C., Bakker, B. M., van Dam, K., Westerhoff, H. V., et al. (2000) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2000.01527.x · Cited by 694
The diverse functions of GAPDH: Views from different subcellular compartments
Tristan, C., Shahani, N., Sedlak, T. W., & Sawa, A. (2011) · Cellular Signalling · doi:10.1016/j.cellsig.2010.08.003 · Cited by 663
Metadata
- Authors
- Singh, R., & Green, M. R.
- Venue
- Science
- Published
- 1993-01-15
- Volume
- 259
- Issue
- 5093
- Pages
- 365-368
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2019922918
- Cited by
- 477
- References
- 30
- FWCI
- 9.99
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
