The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Adoptive cell transfer as personalized immunotherapy for human cancer
Open accessAbstract
Adoptive cell therapy (ACT) is a highly personalized cancer therapy that involves administration to the cancer-bearing host of immune cells with direct anticancer activity. ACT using naturally occurring tumor-reactive lymphocytes has mediated durable, complete regressions in patients with melanoma, probably by targeting somatic mutations exclusive to each cancer. These results have expanded the reach of ACT to the treatment of common epithelial cancers. In addition, the ability to genetically engineer lymphocytes to express conventional T cell receptors or chimeric antigen receptors has further extended the successful application of ACT for cancer treatment.
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Targeting PI3K/Akt signal transduction for cancer therapy
He, Y., Sun, M. M., Zhang, G. G., Yang, J., Chen, K. S., Xu, W. W., & Li, B. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00828-5 · Cited by 1,892
Metadata
- Authors
- Rosenberg, S. A., & Restifo, N. P.
- Venue
- Science
- Published
- 2015-04-03
- Volume
- 348
- Issue
- 6230
- Pages
- 62-68
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1990602451
- Cited by
- 2,506
- References
- 19
- FWCI
- 85.94
- Type
- journal article
- Language
- en
- Open access
- green
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