The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence
Open accessAbstract
Reducing the risk of rearrangement: As lymphocytes develop, they rearrange their antigen receptor genes and proliferate extensively, potentially putting their genomes at risk. Galloway et al. found that two RNA-binding proteins, ZFP36L1 and ZFP36L2, ensure careful entry and exit into the cell cycle. This helps developing B lymphocytes maintain their genomic integrity. Mice deficient in ZFP36L1 and ZFP36L2 exhibited a profound block in B cell development. ZFP36L1 and ZFP36L2 suppress mRNAs that help B cells progress through the cell cycle, ensuring that cells can enter quiescence and keep their genomes safe when they undergo the risky process of rearranging their antigen receptors. Science , this issue p. 453
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mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert
Rodgers, J. T., King, K. Y., Brett, J. O., Cromie, M. J., Charville, G. W., Maguire, K. K., Brunson, C., Mastey, N., Liu, L., Tsai, C.-R., et al. (2014) · Nature · doi:10.1038/nature13255 · Cited by 776
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Metadata
- Authors
- Galloway, A., Saveliev, A., Łukasiak, S., Hodson, D. J., Bolland, D., Balmanno, K., Ahlfors, H., Monzón-Casanova, E., Mannurita, S. C., Bell, L. S., Andrews, S., Díaz-Muñoz, M. D., Cook, S. J., Corcoran, A., & Turner, M.
- Venue
- Science
- Published
- 2016-04-22
- Volume
- 352
- Issue
- 6284
- Pages
- 453-459
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2341872067
- Cited by
- 175
- References
- 6
- FWCI
- 9.59
- Type
- journal article
- Language
- en
- Open access
- green
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- Galloway, A., Saveliev, A., Łukasiak, S., Hodson, D. J., Bolland, D., Balmanno, K., Ahlfors, H., Monzón-Casanova, E., Mannurita, S. C., Bell, L. S., Andrews, S., Díaz-Muñoz, M. D., Cook, S. J., Corcoran, A., & Turner, M. (2016). RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence. Science. https://doi.org/10.1126/science.aad5978
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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