RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS
Ito, Yasushi, Ofengeim, Dimitry, Najafov, Ayaz, Das, Sudeshna, Saberi, Shahram, Li, Ying, Hitomi, Junichi, Zhu, Hong +13 more·2016·Science
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- BindingDB Entry 50014959: Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain.BindingDB · 2023 · UC San Diego
- BindingDB Entry 50000277: Discovery of 7-Oxo-2,4,5,7-tetrahydro-6 H-pyrazolo[3,4- c]pyridine Derivatives as Potent, Orally Available, and Brain-Penetrating Receptor Interacting Protein 1 (RIP1) Kinase Inhibitors: Analysis of Structure-Kinetic Relationships.BindingDB · 2019 · UC San Diego
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- BindingDB Entry 50008478: Small-Molecule Inhibitors of Necroptosis: Current Status and Perspectives.BindingDB · 2021 · UC San Diego
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