The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Apoptosis propagates through the cytoplasm as trigger waves
Open accessAbstract
Visualizing a traveling wave of cell death: When diffusion is too slow for communication over long distances, cells can use waves of chemical activity. By using fluorescent probes and microscopy, Cheng and Ferrell show that in frog eggs (which are very large cells), waves of apoptotic signals can be seen passing through the egg cytoplasm. The pathways that trigger cell death have positive feedback loops that lead to self-regenerating waves. The speed of the waves (∼30 micrometers per minute) is too fast to be explained by diffusion. Science , this issue p. 607
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Cites
Mitochondria and cell death: outer membrane permeabilization and beyond
Tait, S. W. G., & Green, D. R. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2952 · Cited by 2,593
Cited by
Understanding MAPK Signaling Pathways in Apoptosis
Yue, J., & López, J. M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072346 · Cited by 1,245
Modes of Regulated Cell Death in Cancer
Koren, E., & Fuchs, Y. (2021) · Cancer Discovery · doi:10.1158/2159-8290.cd-20-0789 · Cited by 371
Cytoplasmic organization promotes protein diffusion in Xenopus extracts
Huang, W. Y. C., Cheng, X., & Ferrell, J. E. (2022) · Nature Communications · doi:10.1038/s41467-022-33339-0 · Cited by 35
Self-citation
Metadata
- Authors
- Cheng, X., & Ferrell, J. E.
- Venue
- Science
- Published
- 2018-08-10
- Volume
- 361
- Issue
- 6402
- Pages
- 607-612
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2885028350
- Cited by
- 188
- References
- 1
- FWCI
- 5.26
- Type
- journal article
- Language
- en
- Open access
- green
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