Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function
Piwecka, Monika, Glažar, Petar, Hernandez-Miranda, Luis R., Memczak, Sebastian, Wolf, Susanne A., Rybak-Wolf, Agnieszka, Filipchyk, Andrei, Klironomos, Filippos +12 more·2017·Science
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- Circ_ANKIB1 stabilizes the regulation of miR-19b on SOCS3/STAT3 pathway to promote osteosarcoma cell growth and invasionYi‐Xin Du, Linxin Guo, Hansong Pan, Yimin Liang, Xiang Li · 2019 · Human Cell
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- Emerging Roles and Potential Biological Value of CircRNA in OsteosarcomaJiamei Liu, Liyu Yang, Qin Fu, Shengye Liu · 2020 · Frontiers in Oncology
- Aerobic exercise improves VCI through circRIMS2/miR-186/BDNF-mediated neuronal apoptosisYali Niu, Chunxiao Wan, Jing Zhang, Shu Zhang, Zilong Zhao, Leshan Zhu, Xiaodong Wang, Xiaodong Ren, Jing Wang, Ping Lei · 2021 · Molecular Medicine
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- The Value of Circulating Circular RNA in Cancer Diagnosis, Monitoring, Prognosis, and Guiding TreatmentYunjing Zhang, Ying Wang, Xinwan Su, Ping Wang, Weiqiang Lin · 2021 · Frontiers in Oncology
- Small Molecule Drugs Targeting Non-Coding RNAs as Treatments for Alzheimer’s Disease and Related DementiasLien D. Nguyen, Rachel K. Chau, Anna M. Krichevsky · 2021 · Genes
- Integrated Multiomics Reveals Silencing of has_circ_0006646 Promotes TRIM21‐Mediated NCL Ubiquitination to Inhibit Hepatocellular Carcinoma MetastasisXin Hu, Guanrong Chen, Yingchen Huang, Qiyang Cheng, Jianyong Zhuo, Renyi Su, Chiyu He, Yichao Wu, Zhikun Liu, Beng Yang et al. · 2024 · Advanced Science
- Altered nucleocytoplasmic export of adenosine-rich circRNAs by PABPC1 contributes to neuronal functionShi-Meng Cao, Hao Wu, Guo-Hua Yuan, Yu-Hang Pan, Jun Zhang, Yu-Xin Liu, Siqi Li, Yi-Feng Xu, Meng-Yuan Wei, Li Chun Yang et al. · 2024 · Molecular Cell
- Assessment of myoblast circular RNA dynamics and its correlation with miRNA during myogenic differentiationPengpeng Zhang, Haixia Xu, Rui Li, Wei Wu, Zhe Chao, Cencen Li, Wei Xia, Lei Wang, Jinzeng Yang, Yongjie Xu · 2018 · The International Journal of Biochemistry & Cell Biology
- Sponges and Predators in the Small RNA WorldNara Figueroa‐Bossi, Lionello Bossi · 2018 · Microbiology Spectrum
- A Circular RNA from the MDM2 Locus Controls Cell Cycle Progression by Suppressing p53 LevelsRitu Chaudhary, Bruna Rodrigues Muys, Ioannis Grammatikakis, Supriyo De, Kotb Abdelmohsen, Xiao Ling Li, Yuelin Jack Zhu, Swapna Vidhur Daulatabad, Dimitrios Tsitsipatis, Paul S. Meltzer et al. · 2020 · Molecular and Cellular Biology
- Therapeutic Potential of Circular RNAs in OsteosarcomaBen Wan, Hao Hu, Renxian Wang, Weifeng Liu, Dafu Chen · 2020 · Frontiers in Oncology
- Circular RNA expression profiling reveals that circ-PLXNA1 functions in duck adipocyte differentiationLaidi Wang, Wenshuang Liang, Shasha Wang, Zhixiu Wang, Hao Bai, Yong Jiang, Yulin Bi, Guohong Chen, Guobin Chang · 2020 · PLoS ONE
- CircRNAs open a new era in the study of cardiovascular disease (Review)Zhikang Yu, Qingyan Huang, Qunji Zhang, Heming Wu, Zhixiong Zhong · 2020 · International Journal of Molecular Medicine
- The Liver Pre-Metastatic Niche in Pancreatic Cancer: A Potential Opportunity for InterventionPeter Gumberger, Bergþór Björnsson, Per Sandström, Linda Bojmar, Constantinos Pantelis Zambirinis · 2022 · Cancers
- Screening circular RNAs with functional potential using the RfxCas13d/BSJ-gRNA systemSiqi Li, Hao Wu, Ling‐Ling Chen · 2022 · Nature Protocols
- Circular RNA METTL9 contributes to neuroinflammation following traumatic brain injury by complexing with astrocytic SND1Chunling Huang, Lulu Sun, Chenyang Xiao, Wenjun You, Li Sun, Siye Wang, Zhijun Zhang, Su Liu · 2023 · Journal of Neuroinflammation
- CircRNA knockdown based on antisense strategiesGuillermo Aquino‐Jarquín · 2024 · Drug Discovery Today
- Circular RNA vaccines: Pioneering the next-gen cancer immunotherapyUddalak Das, Soupayan Banerjee, Meghna Sarkar, Fathah Muhammad L, Tanveen Kaur Soni, Madhumita Saha, Gayatri Pradhan, Bhaskarjyaa Chatterjee · 2024 · Cancer Pathogenesis and Therapy
- Circular RNAs in Cardiovascular DiseasesLijun Wang, Xiangmin Meng, Guoping Li, Qiulian Zhou, Junjie Xiao · 2018 · Advances in experimental medicine and biology
- Circular RNAs Serve as Novel Biomarkers and Therapeutic Targets in CancersShuai Fang, Jinchang Pan, Chengwei Zhou, Hui Tian, Jinxian He, Weiyu Shen, Xiaofeng Jin, Xiaodan Meng, Nan Jiang, Zhaohui Gong · 2018 · Current Gene Therapy
- circTNFRSF21, a newly identified circular RNA promotes endometrial carcinoma pathogenesis through regulating miR-1227-MAPK13/ATF2 axisYun Liu, Yue Chang, Yixuan Cai · 2020 · Aging
- CircRNAs: Decrypting the novel targets of fibrosis and agingYang Yang, Wangrui Lei, Shuai Jiang, Baoping Ding, Changyu Wang, Ying Chen, Wenzhen Shi, Zhen Wu, Ye Tian · 2021 · Ageing Research Reviews
- Long non‐coding RNA OIP5‐AS1 (Cyrano): A context‐specific regulator of normal and disease processesSerena Wooten, Keriayn N. Smith · 2022 · Clinical and Translational Medicine
- Techniques for investigating lncRNA transcript functions in neurodevelopmentTara Srinivas, Edilene Siqueira Soares, Sònia Guil · 2023 · Molecular Psychiatry
- Regulation of Paneth Cell Function by RNA-Binding Proteins and Noncoding RNAsHee Kyoung Chung, Lan Xiao, Krishna C. Jaladanki, Jian‐Ying Wang · 2021 · Cells
- Advances With Non-coding RNAs in Neuropathic PainCheng Hu, Menglin He, Qian Xu, Weiqian Tian · 2021 · Frontiers in Neuroscience
- The Role of CDR1as in Proliferation and Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem CellsLunyu Yang, Zhang Bin, Shi Hui, Rong Li, Benshuai You, Peipei Wu, Xinye Han, Hui Qian, Wenrong Xu · 2019 · Stem Cells International
- Long noncoding RNA RP11-757G1.5 sponges miR-139-5p and upregulates YAP1 thereby promoting the proliferation and liver, spleen metastasis of colorectal cancerXiaojian Zhu, Fanqin Bu, Ting Tan, Qilin Luo, Jinfeng Zhu, Lin Kang, Jun Huang, Chen Huan Luo, Zhengming Zhu · 2020 · Journal of Experimental & Clinical Cancer Research
- Non-Coding RNAs as Sensors of Oxidative Stress in Neurodegenerative DiseasesAna Gámez‐Valero, Anna Guisado-Corcoll, Marina Herrero‐Lorenzo, Maria Solaguren‐Beascoa, Eulàlia Martı́ · 2020 · Antioxidants
- The Role of Circular RNAs in Pancreatic Ductal Adenocarcinoma and Biliary-Tract CancersChristopher Limb, Daniel Liu, Morten Trillingsgaard Venø, Eleanor Rees, Jonathan Krell, Izhar Bagwan, Elisa Giovannetti, Hardev Pandha, Oliver Strobel, Timothy Rockall et al. · 2020 · Cancers
- Genome-Wide Analysis of the Expression of Circular RNA Full-Length Transcripts and Construction of the circRNA-miRNA-mRNA Network in Cervical CancerTianyi Xu, Xiaofeng Song, Yulan Wang, Shilong Fu, Ping Han · 2020 · Frontiers in Cell and Developmental Biology
- Circular RNAs in the Central Nervous SystemMenglan Li, Wen Wang, Zi‐Bing Jin · 2021 · Frontiers in Molecular Biosciences
- The Role of N6-Methyladenosine Modified Circular RNA in Pathophysiological ProcessesMei Tang, Yonggang Lv · 2021 · International Journal of Biological Sciences
- The Function and Therapeutic Potential of Circular RNA in Cardiovascular DiseasesKai Wang, Xiangqian Gao, Tao Wang, Lu‐Yu Zhou · 2021 · Cardiovascular Drugs and Therapy
- Circular RNA repertoires are associated with evolutionarily young transposable elementsFranziska Gruhl, Peggy Janich, Henrik Kaessmann, David Gatfield · 2021 · eLife
- Locus-Conserved Circular RNA cZNF292 Controls Endothelial Cell Flow ResponsesAndreas W. Heumüller, Alisha N Jones, André Mourão, Marius Klangwart, Chenyue Shi, Ilka Wittig, Ariane Fischer, Marion Muhly-Reinholz, Giulia Buchmann, Christoph Dieterich et al. · 2021 · Circulation Research
- The role and mechanism of noncoding RNAs in regulation of metabolic reprogramming in hepatocellular carcinomaWenwei Liao, Jinpeng Du, Zhen Wang, Qingbo Feng, Mingheng Liao, Huixian Liu, Kefei Yuan, Yong Zeng · 2022 · International Journal of Cancer
- Prediction of COPD acute exacerbation in response to air pollution using exosomal circRNA profile and Machine learningQingtao Meng, Jiajia Wang, Jian Cui, Bin Li, Shenshen Wu, Jun Yun, Michael Aschner, Chengshuo Wang, Luo Zhang, Xiaobo Li et al. · 2022 · Environment International
- CircPCNXL2 promotes tumor growth and metastasis by interacting with STRAP to regulate ERK signaling in intrahepatic cholangiocarcinomaShuochen Liu, Yirui Wang, Tianlin Wang, Kuangheng Shi, Shilong Fan, Chang Li, Ruixiang Chen, Jifei Wang, Wangjie Jiang, Yaodong Zhang et al. · 2024 · Molecular Cancer
- Evolutionary conserved circular MEF2A RNAs regulate myogenic differentiation and skeletal muscle developmentXiaoxu Shen, Xiyu Zhao, Haorong He, Jing Zhao, Yuanhang Wei, Yuqi Chen, Shunshun Han, Yifeng Zhu, Yao Zhang, Qing Chun Zhu et al. · 2023 · PLoS Genetics
- Delivering therapeutic RNA into the brain using extracellular vesiclesPaniz Shirmast, Mahdi Abedinzadeh Shahri, Austin Brent, Adi Idris, Nigel A.J. McMillan · 2024 · Molecular Therapy — Nucleic Acids
- Circular RNAs trigger nonsense-mediated mRNA decaySung Ho Boo, Min-Kyung Shin, Hyun Jung Hwang, Hyeonseo Hwang, Sunwoo Chang, Tae Soo Kim, Daehyun Baek, Yoon Ki Kim · 2024 · Molecular Cell
- The Circular RNome of Developmental Retina in MiceXue‐Jiao Chen, Zicheng Zhang, Xiao-Yun Wang, Hengqiang Zhao, Menglan Li, Yue Ma, Yangyang Ji, Chang-Jun Zhang, Kun‐Chao Wu, Lue Xiang et al. · 2019 · Molecular Therapy — Nucleic Acids
- Circular RNA circCCDC9 alleviates ischaemic stroke ischaemia/reperfusion injury via the Notch pathwayLiquan Wu, Haitao Xu, Wenfei Zhang, Zhibiao Chen, Wenlan Li, Wei Ke · 2020 · Journal of Cellular and Molecular Medicine
- Circular RNA circVMA21 ameliorates lipopolysaccharide (LPS)-induced acute kidney injury by targeting the miR-199a-5p/NRP1 axis in sepsisXimei Li, Rongshan Li, Qingmei Gong, Dongwu Shi, Song Lu, Yu Song · 2021 · Biochemical and Biophysical Research Communications
- Circular RNA expression alteration identifies a novel circulating biomarker in serum exosomal for detection of alcohol dependenceYunyun Liu, Jiande Li, Huanhuan Bu, Hongxuan Wang, Yuanpei Zhang, Qingyu Shen, Mei Li, Zijing Lu, Xiaoming Rong, Dong Zheng et al. · 2021 · Addiction Biology
- Methods to study circRNA-protein interactionsCorinna Jessica Ulshöfer, Christina Pfafenrot, Albrecht Bindereif, Tim P. Schneider · 2021 · Methods
- Circ-Hdgfrp3 shuttles along neurites and is trapped in aggregates formed by ALS-associated mutant FUSEleonora D’Ambra, Tiziana Santini, Erika Vitiello, Sara D’Uva, Valentina Silenzi, Mariangela Morlando, Irene Bozzoni · 2021 · iScience
- rtcisE2F promotes the self-renewal and metastasis of liver tumor-initiating cells via N6-methyladenosine-dependent E2F3/E2F6 mRNA stabilityZhenzhen Chen, Lan Huang, Kaili Wang, Lulu Zhang, Xiang Zhong, Zhongyi Yan, Benyu Liu, Pingping Zhu · 2022 · Science China Life Sciences
- Identification of human genetic variants controlling circular RNA expressionIkhlak Ahmed, Thasni Karedath, Fatima M. Al-Dasim, Joel A. Malek · 2019 · RNA
- Aberrant expression of a novel circular RNA in pancreatic cancerTakahiro Seimiya, Motoyuki Otsuka, Takuma Iwata, Eri Tanaka, Kazuma Sekiba, Chikako Shibata, Masaru Moriyama, Ryo Nakagawa, Reo Maruyama, Kazuhiko Koike · 2020 · Journal of Human Genetics
- Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiationMona Teng, Jiacheng Guo, Xin Xu, Xinpei Ci, Yulin Mo, Yakup Kohen, Zuyao Ni, Sujun Chen, Wang Yuan Guo, Martin K. Bakht et al. · 2025 · Cancer Cell
- A method to directly assay circRNA in real samplesJin Jiao, Tao Gao, Hai Shi, Anzhi Sheng, Yang Xiang, Yongqian Shu, Genxi Li · 2018 · Chemical Communications
- An evolutionarily conserved RNA structure in the functional core of the lincRNA CyranoAlisha N Jones, Giuseppina Pisignano, Thomas Pavelitz, Jessica White, Martin Kinisu, Nicholas M. Forino, Dreycey Albin, Gabriele Varani · 2020 · RNA
- CircZNF652 promotes the goblet cell metaplasia by targeting the miR-452-5p/JAK2 signaling pathway in allergic airway epitheliaXiangzhi Wang, Chengyun Xu, Yuqing Cai, Xinyi Zou, Yun-Qi Chao, Ziyi Yan, Chaochun Zou, Ximei Wu, Lanfang Tang · 2022 · Journal of Allergy and Clinical Immunology
- Genetic tools for the stable overexpression of circular RNAsNicol Mecozzi, Arianna Nenci, Olga Vera, Ilah Bok, Aimee Falzone, Gina M. DeNicola, Florian A. Karreth · 2022 · RNA Biology
- Current advances and future perspectives on the functional roles and clinical implications of circular RNAs in esophageal squamous cell carcinoma: more influential than expectedChenxi Ju, Jing He, Chang Wang, Jinxiu Sheng, Jinlin Jia, Dan Du, Hongle Li, Mingxia Zhou, Fucheng He · 2022 · Biomarker Research
- circRNA : Regulatory factors and potential therapeutic targets in inflammatory dermatosesRuifeng Liu, Luyao Zhang, Xincheng Zhao, Jia Liu, Wenjuan Chang, Ling Zhou, Kaiming Zhang · 2022 · Journal of Cellular and Molecular Medicine
- RasGRP1 promotes the acute inflammatory response and restricts inflammation-associated cancer cell growthCong Wang, Xue Li, Binbin Xue, Changping Yu, Luoling Wang, Rilin Deng, Hui Liu, Zihao Chen, Yingdan Zhang, Suping Fan et al. · 2022 · Nature Communications
- Identification and characterization of circular RNAs during wood formation of poplars in acclimation to low nitrogen availabilityHuimin Liu, Wanwen Yu, Jiangting Wu, Zhuorong Li, Hui Li, Jing Zhou, Jingjing Hu, Yan Lu · 2020 · Planta
- Circular RNAs profiling in the cystathionine-β-synthase mutant mouse reveals novel gene targets for hyperhomocysteinemia induced ocular disordersMahavir Singh, Akash K. George, Rubens P. Homme, Avisek Majumder, Anwesha Laha, Harpal Singh Sandhu, Suresh C. Tyagi · 2018 · Experimental Eye Research
- A circular RNA derived from COL6A3 functions as a ceRNA in gastric cancer developmentXiaoli Sun, Xinwu Zhang, Hongjun Zhai, Di Zhang, Shuangyu Ma · 2019 · Biochemical and Biophysical Research Communications
- Biogenesis of circular RNAs and their role in cellular and molecular phenotypes of neurological disordersBS Guerra, Joni Esrom Lima, BHS Araujo, L.A.G.M.M. Torres, J.X. Santos, DJS Machado, EBB Cunha, JA Serrato, JS de Souza, JV Martins et al. · 2020 · Seminars in Cell and Developmental Biology
- NSL2CD: identifying potential circRNA–disease associations based on network embedding and subspace learningQiu Xiao, Yu Fu, Yide Yang, Jianhua Dai, Jiawei Luo · 2021 · Briefings in Bioinformatics
- PINTology : A short history of the lncRNA LINC‐PINT in different diseasesIhtisham Bukhari, Muhammad Riaz Khan, Mohammed Amir Husain, Rick Francis Thorne, Yong Yu, Bingyong Zhang, Pengyuan Zheng, Yang Mi · 2022 · Wiley Interdisciplinary Reviews - RNA
- Non-coding RNAs in enzalutamide resistance of castration-resistant prostate cancerKe Gao, Xiaoshun Li, Jianxin Ni, Bing Wu, Jiaheng Guo, Rui Zhang, Guojun Wu · 2023 · Cancer Letters
- The Ever-Evolving Concept of the Gene: The Use of RNA/Protein Experimental Techniques to Understand Genome FunctionsAndrea Cipriano, Monica Ballarino · 2018 · Frontiers in Molecular Biosciences
- The spatiotemporal expression pattern of microRNAs in the developing mouse nervous systemPengcheng Shu, Chao Wu, Wei Liu, Xiangbin Ruan, Chang Liu, Lin Hou, Yi Zeng, Hongye Fu, Ming Wang, Pan Chen et al. · 2018 · Journal of Biological Chemistry
- Topology-Sensitive Microfluidic Filter for Polymers of Varying StiffnessLisa B. Weiss, Arash Nikoubashman, Christos N. Likos · 2017 · ACS Macro Letters
- MicroRNA miR-7 and miR-17-92 in the Arcuate Nucleus of Mouse Hypothalamus Regulate Sex-Specific Diet-Induced ObesityYan-Xia Gao, Jiaheng Li, Zhen Zhang, Ruihan Zhang, Andrew Pollock, Tao Sun · 2019 · Molecular Neurobiology
- Multimodal Long Noncoding RNA Interaction Networks: Control Panels for Cell Fate SpecificationKeriayn N. Smith, Sarah C. Miller, Gabriele Varani, J. Mauro Calabrese, Terry Magnuson · 2019 · Genetics
- Circular RNAs in nasopharyngeal carcinomaMingxiu Yang, Weiguo Huang · 2020 · Clinica Chimica Acta
- Genome-Wide Circular RNA Expression Patterns Reflect Resistance to Immunomodulatory Drugs in Multiple Myeloma CellsTheresa Jakobsen, Mette Dahl, Konstantinos Dimopoulos, Kirsten Grønbæk, Jørgen Kjems, Lasse S. Kristensen · 2021 · Cancers
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- Exploring the Multifaceted Biologically Relevant Roles of circRNAs: From Regulation, Translation to BiomarkersParsa Hoque, Brigette Romero, Robert E. Akins, Mona Batish · 2023 · Cells
- Down-regulation of circ-PRKCI inhibits cell migration and proliferation in Hirschsprung disease by suppressing the expression of miR-1324 target PLCB1Lingling Zhou, Li Yang, Weiwei Jiang, Hua Zhang, Zechao Wen, Yang Su, Feng Wu, Zhengke Zhi, Qiyang Shen, Hongxing Li et al. · 2018 · Cell Cycle
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- Circular RNAs: Potential Applications as Therapeutic Targets and Biomarkers in Breast CancerDebina Sarkar, Sarah D. Diermeier · 2021 · Non-Coding RNA
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- Circular RNAs as Novel Diagnostic Biomarkers and Therapeutic Targets in Kidney DiseaseJianwen Yu, Danli Xie, Naya Huang, Qin Zhou · 2021 · Frontiers in Medicine