Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Love, M. I., Huber, W., & Anders, S. (2014) · Genome Biology · doi:10.1186/s13059-014-0550-8 · Cited by 95,106

Fast gapped-read alignment with Bowtie 2

Langmead, B., & Salzberg, S. L. (2012) · Nature Methods · doi:10.1038/nmeth.1923 · Cited by 56,400

STAR: ultrafast universal RNA-seq aligner

Dobin, A., Davis, C. A., Schlesinger, F., Drenkow, J., Zaleski, C., Jha, S., Batut, P., Chaisson, M., & Gingeras, T. R. (2013) · Bioinformatics · doi:10.1093/bioinformatics/bts635 · Cited by 51,709

MUSCLE: multiple sequence alignment with high accuracy and high throughput

Edgar, R. C. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh340 · Cited by 44,662

HTSeq—a Python framework to work with high-throughput sequencing data

Anders, S., Pyl, P. T., & Huber, W. (2015) · Bioinformatics · doi:10.1093/bioinformatics/btu638 · Cited by 21,464

Multiplex Genome Engineering Using CRISPR/Cas Systems

Cong, L., Ran, F. A., Cox, D., Lin, S., Barretto, R., Habib, N., Hsu, P. D., Wu, X., Jiang, W., Marraffini, L. A., et al. (2013) · Science · doi:10.1126/science.1231143 · Cited by 15,339

Genome engineering using the CRISPR-Cas9 system

Ran, F. A., Hsu, P. D., Wright, J., Agarwala, V., Scott, D. A., & Zhang, F. (2013) · Nature Protocols · doi:10.1038/nprot.2013.143 · Cited by 11,133

Circular RNAs are a large class of animal RNAs with regulatory potency

Memczak, S., Jens, M., Elefsinioti, A., Torti, F., Krueger, J., Rybak, A., Maier, L., Mackowiak, S. D., Gregersen, L. H., Munschauer, M., et al. (2013) · Nature · doi:10.1038/nature11928 · Cited by 7,990

Natural RNA circles function as efficient microRNA sponges

Hansen, T. B., Jensen, T. I., Clausen, B. H., Bramsen, J. B., Finsen, B., Damgaard, C. K., & Kjems, J. (2013) · Nature · doi:10.1038/nature11993 · Cited by 7,985

Predicting effective microRNA target sites in mammalian mRNAs

Agarwal, V., Bell, G. W., Nam, J.-W., & Bartel, D. P. (2015) · eLife · doi:10.7554/elife.05005 · Cited by 7,318

Circular RNA mapping reveals CircCWC22 as a MiR-3059-x sponge in yak fat deposition by regulating HMGCL

Qin, C., Wang, H., Peng, W., Yue, B., Fu, C., Shu, S., Zhong, J., & Wang, H. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.128531 · Cited by 13

Circular RNA circASH1L(4,5) protects microRNA-129-5p from target-directed microRNA degradation in human skin wound healing

Wang, Q., Niu, G., Liu, Z., Toma, M. A., Geara, J., Bian, X., Zhang, L., Piipponen, M., Li, D., Wang, A., et al. (2024) · British Journal of Dermatology · doi:10.1093/bjd/ljae405 · Cited by 13

A read-through circular RNA RCRIN inhibits metabolic dysfunction-associated steatotic liver disease

Wang, Y., Wang, J., Zhou, Z., Gu, Y., Zhu, X., Yi, Z., Cao, C., He, L., Du, Y., Guo, H., et al. (2024) · Journal of Hepatology · doi:10.1016/j.jhep.2024.11.052 · Cited by 13

Establishing essential quality criteria for the validation of circular RNAs as biomarkers

Pfafenrot, C., & Preußer, C. (2019) · Biomolecular Detection and Quantification · doi:10.1016/j.bdq.2019.100085 · Cited by 13

Circular RNA rno_circ_0004002 regulates cell proliferation, apoptosis, and epithelial‐mesenchymal transition through targeting miR‐342‐5p and Wnt3a in anorectal malformations

Qu, Y., Liu, D., Jia, H., & Yang, Z. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.28814 · Cited by 13

Tagger—A Swiss army knife for multiomics to dissect cell type–specific mechanisms of gene expression in mice

Kaczmarczyk, L., Bansal, V., Rajput, A., Rahman, R., Krzyżak, W., Degen, J., Poll, S., Fuhrmann, M., Bonn, S., & Jackson, W. S. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000374 · Cited by 13

Regulation of the parental gene GRM4 by circGrm4 RNA transcript and glutamate-mediated neurovascular toxicity in eyes

Eyob, W., George, A. K., Homme, R., Stanišić, D., Sandhu, H., Tyagi, S., & Singh, M. (2020) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-020-03934-0 · Cited by 10

circ_SEPT9, a newly identified circular RNA, promotes oral squamous cell carcinoma progression through miR‐1225/PKN2 axis

Ai, Y., Tang, Z., Zou, C., Wei, H., Wu, S., & Huang, D. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15943 · Cited by 13

Role of Non-Coding RNA of Human Platelet in Cardiovascular Disease

Inzulza-Tapia, A., & Alarcón, M. A. (2021) · Current Medicinal Chemistry · doi:10.2174/0929867329666211230104955 · Cited by 13

Physiologically relevant miRNAs in mammalian oocytes are rare and highly abundant

Kataruka, S., Kinterová, V., Horvat, F., Kulmann, M. I. R., Kaňka, J., & Svoboda, P. (2021) · EMBO Reports · doi:10.15252/embr.202153514 · Cited by 13

Profile of TREM2-Derived circRNA and mRNA Variants in the Entorhinal Cortex of Alzheimer’s Disease Patients

Urdánoz‐Casado, A., de Gordoa, J. S., Robles, M., Roldán, M., Zelaya, M. V., Blanco‐Luquin, I., & Mendióroz, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147682 · Cited by 13

Circular RNAs as a promising biomarker for heart disease

Kim, Y. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113935 · Cited by 13

A circular RNA Edis-Relish-castor axis regulates neuronal development in Drosophila

Liu, W., Liang, W., Xiong, X.-P., Li, J., & Zhou, R. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1010433 · Cited by 13

Cancer Stem Cells—The Insight into Non-Coding RNAs

Bryl, R., Piwócka, O., Kawka, E., Mozdziak, P. E., Kempisty, B., & Knopik-Skrocka, A. (2022) · Cells · doi:10.3390/cells11223699 · Cited by 14

Assessing the impacts of various factors on circular RNA reliability

Chuang, T., Chiang, T.-W., & Chen, C.-Y. (2023) · Life Science Alliance · doi:10.26508/lsa.202201793 · Cited by 13

Circular RNAs: pivotal role in the leukemogenesis and novel indicators for the diagnosis and prognosis of acute myeloid leukemia

Rahmati, A., Mafi, A., Soleymani, F., Aghdam, Z. B., Masihipour, N., Ghezelbash, B., Asemi, R., Aschner, M., Vakili, O., Homayoonfal, M., et al. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1149187 · Cited by 13

Dysregulation of circular RNAs in inflammation and cancers

Liu, J., Zhao, F., Chen, L., & Su, S. (2023) · Fundamental Research · doi:10.1016/j.fmre.2023.04.019 · Cited by 13

Circular RNAs in hepatocellular carcinoma: biogenesis, function, and pathology

Rao, G., Peng, X., Tian, Y., Fu, X., & Zhang, Y. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1106665 · Cited by 13

CircZCCHC2 decreases pirarubicin sensitivity and promotes triple-negative breast cancer development via the miR-1200/TPR axis

Zhang, F., Wei, D., Xie, S., Ren, L., Qiao, S., Li, L., Ji, J., & Fan, Z. (2024) · iScience · doi:10.1016/j.isci.2024.109057 · Cited by 13

Dynamic Expression Profiles of Circular RNAs during Brown to White Adipose Tissue Transformation in Goats (Capra hircus)

Zhang, X., Zhan, S., Yang, S., Zhong, T., Guo, J., Cao, J., Wang, Y., Li, L., Zhang, H., & Wang, L. (2021) · Animals · doi:10.3390/ani11051351 · Cited by 13

Circular RNAs acting as ceRNAs mediated by miRNAs may be involved in the synthesis of soybean fatty acids

Ma, B., Liu, Z., Yan, W., Wang, L., He, H., Zhang, A., Li, Z., Zhao, Q., Liu, M., Guan, S., et al. (2021) · Functional & Integrative Genomics · doi:10.1007/s10142-021-00791-y · Cited by 13

Research Progress on Circular RNA in Glioma

Chen, M., Yan, C., & Zhao, X. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.705059 · Cited by 13

MicroRNA‑203‑3p inhibits the proliferation, invasion and migration of pancreatic cancer cells by downregulating fibroblast growth factor 2

Fu, X., Zhao, H., Chen, C.-Z., Wang, K., Gao, F., Tian, Y.-Z., Li, H.-Y., & Zhao, H. (2021) · Oncology Letters · doi:10.3892/ol.2021.12887 · Cited by 13

Circular RNAs in Cardiovascular Disease: Mechanisms, Biomarkers, and Therapeutic Frontiers

Alali, R. A., Almansori, M., Vatte, C., Akhtar, M. S., Abduljabbar, S. S., Al-Matroud, H., Alnuwaysir, M. J., Radhi, H. A., Keating, B. J., Habara, A. H., et al. (2025) · Biomolecules · doi:10.3390/biom15101455 · Cited by 12

Non-coding RNA regulates the immune microenvironment in recurrent spontaneous abortion (RSA): new insights into immune mechanisms

Tang, C., & Hu, W. (2023) · Biology of Reproduction · doi:10.1093/biolre/ioad157 · Cited by 12

Circular RNAs and their roles in idiopathic pulmonary fibrosis

Surendran, A. M., Huang, C., & Liu, L. (2024) · Respiratory Research · doi:10.1186/s12931-024-02716-2 · Cited by 13

Exploring the oncogenic and tumor-suppressive roles of Circ-ADAM9 in cancer

Hussain, M. S., Moglad, E. H. O., Bansal, P., Kaur, H., Deorari, M., Almalki, W. H., Kazmi, I. A., Alzarea, S. I., Singh, M., & Kukreti, N. (2024) · Pathology - Research and Practice · doi:10.1016/j.prp.2024.155257 · Cited by 12

Competing endogenous RNAs regulatory crosstalk networks: The messages from the RNA world to signaling pathways directing cancer stem cell development

Aria, H., Azizi, M., Nazem, S., Mansoori, B., Darbeheshti, F., Niazmand, A., Daraei, A., & Mansoori, Y. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e35208 · Cited by 12

Ancestral retrovirus envelope protein ERVWE1 upregulates circ_0001810, a potential biomarker for schizophrenia, and induces neuronal mitochondrial dysfunction via activating AK2

Li, W., Xue, X., Li, X., Wu, X., Zhou, P., Xia, Y., Zhang, J., Zhang, M., & Zhu, F. (2024) · Cell & Bioscience · doi:10.1186/s13578-024-01318-1 · Cited by 13

Competing endogenous RNAs network and therapeutic implications: New horizons in disease research

El‐Ashmawy, N. E., Khedr, E. G., Darwish, R. T., & Ibrahim, A. O. (2024) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2024.195073 · Cited by 12

Microbial modulation of plant epigenetics: the role of miRNA and lncRNA in enhancing salt tolerance

Salunke, T. R., Sontakke, O. P., Chavan, S. C., Bhosale, K. S., Wayase, U. R., Barmukh, R. B., Ahire, M. L., Shelar, P. V., Nikalje, G. C., & Mankar, G. D. (2025) · Discover Plants. · doi:10.1007/s44372-025-00249-6 · Cited by 12

circRNA‐14723 promotes hepatocytes proliferation in rat liver regeneration by sponging rno‐miR‐16‐5p

Guo, X., Xi, L., Li, L., Guo, J., Jin, W., Chang, C., Zhang, J., Xu, C., & Chen, G. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29473 · Cited by 12

Emerging role of circular RNA in intervertebral disc degeneration: Knowns and unknowns (Review)

Li, Y., Zhou, S., Peng, P., Wang, X., Du, L., Huo, Z., & Xu, B. (2020) · Molecular Medicine Reports · doi:10.3892/mmr.2020.11437 · Cited by 12

CircSPIDR acts as a tumour suppressor in cervical adenocarcinoma by sponging miR-431-5p and regulating SORCS1 and CUBN expression

Xu, J., & Lü, W. (2021) · Aging · doi:10.18632/aging.203283 · Cited by 12

Characterization of Circular RNAs

Zhang, Y., Yang, L. C., & Chen, L. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1697-0_16 · Cited by 12

Targeting circDGKD Intercepts TKI’s Effects on Up-Regulation of Estrogen Receptor β and Vasculogenic Mimicry in Renal Cell Carcinoma

Ding, J., Cui, X., Chen, H., Sun, Y., Yu, W., Luo, J., Xiao, G., Chang, C., Qi, J., & Yeh, S. (2022) · Cancers · doi:10.3390/cancers14071639 · Cited by 12

Identification of Functional CircRNA–miRNA–mRNA Regulatory Network in Dorsolateral Prefrontal Cortex Neurons of Patients With Cocaine Use Disorder

Chen, Y., Li, X., Meng, S., Huang, S., Chang, S., & Shi, J. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.839233 · Cited by 12

Non-Coding RNA Networks as Potential Novel Biomarker and Therapeutic Target for Sepsis and Sepsis-Related Multi-Organ Failure

Raimondo, D. D., Pirera, E., Rizzo, G., Simonetta, I., Musiari, G., & Tuttolomondo, A. (2022) · Diagnostics · doi:10.3390/diagnostics12061355 · Cited by 12

CircRNAs: novel therapeutic targets in multiple myeloma

Zhou, X., & Du, J. (2022) · Molecular Biology Reports · doi:10.1007/s11033-022-07668-8 · Cited by 12

Hsa_Circ_0000826 inhibits the proliferation of colorectal cancer by targeting AUF1

Zhang, Z., Fan, W., Gao, Q., Han, Y., Ma, J., Gao, W., Hu, Y., Zhu, H., Yang, R. R., Wang, H., et al. (2022) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2022.07.006 · Cited by 12

The circRNA circADAMTS6 promotes progression of ESCC and correlates with prognosis

Bu, J., Gu, L., Liu, X., Nan, X., Zhang, X., Meng, L., Zheng, Y., Liu, F., Li, J., Li, Z., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-17450-2 · Cited by 12

CircCSDE1 Regulates Proliferation and Differentiation of C2C12 Myoblasts by Sponging miR-21-3p

Sun, D., An, J., Cui, Z., Li, J., You, Z., Lu, C., Yang, Y., Gao, P., Guo, X., Li, B., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231912038 · Cited by 12

Circular RNA hsa_circ_0004689 (circSWT1) promotes NSCLC progression via the miR‐370‐3p/SNAIL axis by inducing cell epithelial‐mesenchymal transition (EMT)

Long, X., Wang, D., Wu, Z., Liao, Z., & Xu, J. (2022) · Cancer Medicine · doi:10.1002/cam4.5527 · Cited by 12

cRNAsp12 Web Server for the Prediction of Circular RNA Secondary Structures and Stabilities

Wang, F., Li, W., Li, B., Xie, L., Tong, Y., & Xu, X. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043822 · Cited by 12

Enhanced Tailored MicroRNA Sponge Activity of RNA Pol II-Transcribed TuD Hairpins Relative to Ectopically Expressed ciRS7-Derived circRNAs

Hollensen, A. K., Andersen, S., Hjorth, K., Bak, R. O., Hansen, T. B., Kjems, J., Aagaard, L., Damgaard, C. K., & Mikkelsen, J. G. (2018) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2018.09.009 · Cited by 12

Circular RNA UVRAG Mediated by Alternative Splicing Factor NOVA1 Regulates Adhesion and Migration of Vascular Smooth Muscle Cells

Liu, Z., Lou, Y., Cui, J.-C., Chen, Y., Liu, J.-T., Yuan, Y., Han, Y., Huo, Y., Qi, Y., Jiang, Z., et al. (2021) · Genes · doi:10.3390/genes12030418 · Cited by 12

Direct Interaction of miRNA and circRNA with the Oncosuppressor p53: An Intriguing Perspective in Cancer Research

Bizzarri, A. R., & Cannistraro, S. (2021) · Cancers · doi:10.3390/cancers13236108 · Cited by 12

Commentary: FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons

Verheijen, B. M., & Pasterkamp, R. J. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00412 · Cited by 13

RNA biomarkers for alcohol use disorder

Ferguson, L. B., Mayfield, R. D., & Messing, R. O. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.1032362 · Cited by 12

Circ_0000235 targets MCT4 to promote glycolysis and progression of bladder cancer by sponging miR-330-5p

Zhong, J., Xu, A., Xu, P., Su, M., Wang, P., Liu, Z., Li, B., Liu, C., & Jiang, N. (2023) · Cell Death Discovery · doi:10.1038/s41420-023-01582-z · Cited by 11

CPSF3 Promotes Pre-mRNA Splicing and Prevents CircRNA Cyclization in Hepatocellular Carcinoma

Huang, Y., Dong, J., wang, X., Ji, H., He, Z., Cheng, Z., & Zhu, Q. (2023) · Cancers · doi:10.3390/cancers15164057 · Cited by 11

Circular RNA in Cardiovascular Diseases: Biogenesis, Function and Application

Mei, S., Ma, X., Li, Z., Wuyun, Q., Cai, Z., Yan, J., & Ding, H. (2024) · Biomolecules · doi:10.3390/biom14080952 · Cited by 11

Role of Virally Encoded Circular RNAs in the Pathogenicity of Human Oncogenic Viruses

Avilala, J., Becnel, D. M., Abdelghani, R., Nanbo, A., Kahn, J., Li, L., & Lin, Z. N. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.657036 · Cited by 13

Multiple novel functions of circular RNAs in diabetes mellitus

Tehrani, S. S., Goodarzi, G., Panahi, G., Maniati, M., & Meshkani, R. (2021) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2021.1933047 · Cited by 11

Crosstalk Between MicroRNAs and Circular RNAs in Human Diseases: A Bibliographic Study

Chen, Y., Zheng, Y.-L., Su, X., & Wang, X. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.754880 · Cited by 11

Hotspots and development frontiers of circRNA based on bibliometric analysis

Zhang, C., Kang, Y., Kong, F., Yang, Q., & Chang, D. (2022) · Non-coding RNA Research · doi:10.1016/j.ncrna.2022.03.001 · Cited by 11

An Overview of the Advances in Research on the Molecular Function and Specific Role of Circular RNA in Cardiovascular Diseases

Yin, L., Tang, Y., & Yuan, Y. (2022) · BioMed Research International · doi:10.1155/2022/5154122 · Cited by 11

Type 1 Diabetes Mellitus‐Related circRNAs Regulate CD4+ T Cell Functions

Chen, J., Jia, G., Lv, X., & Li, S. (2022) · BioMed Research International · doi:10.1155/2022/4625183 · Cited by 11

Exosomal circRNAs: A key factor of tumor angiogenesis and therapeutic intervention

Zhang, X.-P., Pei, J., Zhang, C., Yusupu, M., Han, M.-H., & Dai, D. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113921 · Cited by 12

Circular RNA-FK501 binding protein 51 boosts bone marrow mesenchymal stem cell proliferation and osteogenic differentiation via modulating microRNA-205-5p/Runt-associated transcription factor 2 axis

Shen, Y., Jiang, B., Luo, B., Jiang, X., Zhang, Y., & Wang, Q. (2023) · Journal of Orthopaedic Surgery and Research · doi:10.1186/s13018-023-04242-1 · Cited by 11

MiRNA: a potential target for gene diagnosis and treatment of atherosclerotic stroke

Bao, Y., Li, S., Ding, Y., Du, X., Zhang, M., Tang, W., & Zhou, S. (2020) · International Journal of Neuroscience · doi:10.1080/00207454.2020.1738428 · Cited by 12

Circular RNA expression alteration in whole blood of premature infants with periventricular white matter damage

Qiao, L., Mo, S., Zhou, Y., Zhang, Y., Li, B., Wu, S., Lin, L., Zhu, L., & Zhao, R. (2020) · Genomics · doi:10.1016/j.ygeno.2020.03.027 · Cited by 11

Screening and bioinformatics analysis of a ceRNA network based on the circular RNAs, miRNAs, and mRNAs in pan‐cancer

Chen, Z., Huang, J., Feng, Y., Li, Z., & Jiang, Y. (2020) · Cancer Medicine · doi:10.1002/cam4.3375 · Cited by 11

Identification of Circular RNA Expression Profiles and Potential Biomarkers for Intracerebral Hemorrhage

Bai, C., Liu, T., Sun, Y., Li, H., Xiao, N., Zhang, M., Feng, Y., Xu, H., Ge, J., Wang, X., et al. (2021) · Epigenomics · doi:10.2217/epi-2020-0432 · Cited by 11

A single small molecule fluorescent probe for imaging RNA distribution and detecting endogenous SO 2 through distinct fluorescence channels

Wang, Z., Liu, Y., Wang, W., Zhao, C., & Lin, W. (2021) · New Journal of Chemistry · doi:10.1039/d1nj03588f · Cited by 11

Circular and Fusion RNAs in Medulloblastoma Development

Azatyan, A., & Zaphiropoulos, P. G. (2022) · Cancers · doi:10.3390/cancers14133134 · Cited by 11

Tip of the iceberg: roles of circRNAs in hematological malignancies.

Guo, S., Li, B., Zou, D., Yang, S.-J., Sheng, L., Ouyang, G., Mu, Q., & Huang, H. (2020) · PubMed Central · Cited by 11

Regulation of neuronal circHomer1 biogenesis by PKA/CREB/ERK-mediated pathways and effects of glutamate and dopamine receptor blockade.Preprint

Mellios, N., Papageorgiou, G., Gorgievski, V., Maxson, G., Hernandez, M., Otero, M. P., Varangis, M., Dell’Orco, M., Perrone‐Bizzozero, N. I., & Tzavara, E. T. (2024) · Research Square · doi:10.21203/rs.3.rs-3547375/v1 · Cited by 11

CircHTT(2,3,4,5,6) — co-evolving with the HTT CAG-repeat tract — modulates Huntington's disease phenotypes

Morandell, J., Monziani, A., Lazioli, M., Donzel, D., Döring, J., Pegorar, C. O., D’Anzi, A., Pellegrini, M., Mattiello, A., Bortolotti, D., et al. (2024) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2024.102234 · Cited by 10

Systematic loss-of-function screens identify pathway-specific functional circular RNAs

Liu, L., Neve, M., Perlaza-Jiménez, L., Xi, X., Purcell, J., Hawdon, A., Conn, S. J., Zenker, J., Tamayo, P., Goodall, G. J., et al. (2024) · Nature Cell Biology · doi:10.1038/s41556-024-01467-y · Cited by 10

EIciRNAs in focus: current understanding and future perspectives

Yang, Y., Zhong, Y., & Chen, L. (2024) · RNA Biology · doi:10.1080/15476286.2024.2443876 · Cited by 10

Inter-chromosomal insertions at Xq27.1 associated with retinal dystrophy induce dysregulation of LINC00632 and CDR1as/ciRS-7

Gardner, J. C., Jovanovic, K., Ottaviani, D., Melo, U. S., Jackson, J., Guarascio, R., Ziaka, K., Hau, K.-L., Lane, A., Taylor, R. L., et al. (2025) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2025.01.007 · Cited by 10

Circular RNAs as disease modifiers of complex neurologic disorders

Galli, V., Vinciguerra, S., Biagioli, M., & Morandell, J. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1577496 · Cited by 10

Circular RNAs as central regulators of metabolic reprogramming and immune responses in the breast cancer microenvironment: A comprehensive review

Sherafat, N. S., Mardi, A., Absalan, F., & Mehmandar‐Oskuie, A. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118682 · Cited by 11

Diversity of circular RNAs and RNA ligases in archaeal cells

Becker, H. F., L'Hermitte-Stead, C., & Myllykallio, H. (2019) · Biochimie · doi:10.1016/j.biochi.2019.06.011 · Cited by 10

Circular RNAs in gastrointestinal cancer: Current�knowledge, biomarkers and targeted therapy (Review)

Zhao, X., Wang, Y., Yu, Q., Yu, P., Zheng, Q., Yang, X., & Gao, D. (2020) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2020.4731 · Cited by 10

Bioinformatics Analysis of circRNA Expression and Construction of “circRNA-miRNA-mRNA” Competing Endogenous RNAs Networks in Bipolar Disorder Patients

Fu, Y., He, W., Zhou, C., Fu, X., Wan, Q., He, L., & Wei, B. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.718976 · Cited by 10

Noncoding RNAs in cataract formation: Star molecules emerge in an endless stream

Chen, S., Zhang, C., Shen, L., Hu, J., Chen, X., & Yu, Y. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106417 · Cited by 11

Emerging roles of circular RNAs in tuberculosis

Wang, Q., Yang, D., Zuo, Y., Wang, D., & Li, W. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.995701 · Cited by 11

Circular RNAs in organ injury: recent development

Wong, R. T. C., Zhang, Y., Zhao, H., & Ma, D. (2022) · Journal of Translational Medicine · doi:10.1186/s12967-022-03725-9 · Cited by 11

Virus-Encoded Circular RNAs: Role and Significance in Viral Infections

Sberna, G., Maggi, F., & Amendola, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216547 · Cited by 11

CircRNAs as New Therapeutic Entities and Tools for Target Identification in Acute Myeloid Leukemia

Nopora, A., & Weidle, U. H. (2024) · Cancer Genomics & Proteomics · doi:10.21873/cgp.20434 · Cited by 11

Biological functions of circRNA in regulating the hallmarks of gastrointestinal cancer (Review)

Qiu, M.-J., Chen, Y., & Zeng, C. (2024) · International Journal of Oncology · doi:10.3892/ijo.2024.5637 · Cited by 10

Functional role of circRNA CHRC through miR-431-5p/KLF15 signaling axis in the progression of heart failure

Hu, Y., Cao, H., Sheng, J., Sun, Y., Zhu, Y., Lin, Q., Yi, N., He, S., Peng, L., & Li, L. (2024) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2024.03.010 · Cited by 10

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Mafi, A., Hedayati, N., Milasi, Y. E., Kahkesh, S., Daviran, M., Farahani, N., Hashemi, M., Nabavi, N., Alimohammadi, M., Rahimzadeh, P., et al. (2024) · Pathology - Research and Practice · doi:10.1016/j.prp.2024.155457 · Cited by 11

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Woolard, E., & Chorley, B. N. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812433-8.00009-5 · Cited by 10

Comprehensive analysis of circRNAs expression profiles in different periods of MDBK cells infected with bovine viral diarrhea virus

Li, C., Li, X., Hou, X., Ni, W., Zhang, M., Li, H., Xu, Y., Hazi, W., Ma, Q., Zhang, Y., et al. (2019) · Research in Veterinary Science · doi:10.1016/j.rvsc.2019.05.005 · Cited by 10

Circular RNAs and Its Biological Functions in Health and Disease

Sağlam, A. S. Y., Alp, E., & Önen, H. İ. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.88764 · Cited by 10

Promotion of Bronchopulmonary Dysplasia Progression Using Circular RNA circabcc4 via Facilitating PLA2G6 Expression by Sequestering miR-663a

Chen, Y., Feng, D.-D., Wu, S., Lu, H., Pasha, A. B., Permall, D. L., Chen, J., Sun, Z., Li, B., Zhou, H., et al. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.585541 · Cited by 10

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Huang, M., Dong, J., Guo, H., Xiao, M., & Wang, D. (2021) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2021.104994 · Cited by 10

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Ivanov, A., Mattei, D., Radscheit, K., Compagnion, A., Pett, J. P., Herzel, H., Paolicelli, R. C., Piwecka, M., Meyer, U., & Beule, D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012347 · Cited by 12

Construction and analysis of circular RNA-associated competing endogenous RNA network in the hippocampus of aged mice for the occurrence of postoperative cognitive dysfunction

Zhang, M., Suo, Z., Qu, Y., Zheng, Y., Xu, W., Zhang, B., Wang, Q., Wu, L., Li, S., Cheng, Y., et al. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1098510 · Cited by 10

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Shao, Y., Li, H., Du, R., Meng, J., & Yang, G. S. (2018) · Journal of Cancer · doi:10.7150/jca.24550 · Cited by 10

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Dori, M., Alieh, L. H. A., Cavalli, D., Massalini, S., Lesche, M., Dahl, A., & Calegari, F. (2019) · Life Science Alliance · doi:10.26508/lsa.201900354 · Cited by 10

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Li, X., Li, L., Si, X., Zhang, Z., Ni, Z., Zhou, Y., Liu, K., Xia, W., Zhang, Y., Gu, X., et al. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.963508 · Cited by 9

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Jasny, B. R. (2017) · Science · doi:10.1126/science.357.6357.1250-m

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Yates, D. M. (2017) · Nature reviews. Neuroscience · doi:10.1038/nrn.2017.118 · Cited by 3

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Cerda, C., Kim, S. J., Thomas, G., Farsi, Z., Zolotarov, G., Georgii, E., Woehler, A., Piwecka, M., & Rajewsky, N. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.01.26.525729 · Cited by 3

The history and function of a circular RNA

Cerda, C., Scoyni, F., Zolotarov, G., Bhaskar, P., León-Periñán, D., Kjems, J., & Rajewsky, N. (2026) · Nature Communications · doi:10.1038/s41467-026-71822-0 · Cited by 5