Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease
Burbulla, Lena F., Song, Pingping, Mazzulli, Joseph R., Zampese, Enrico, Wong, Yvette C., Jeon, Sohee, Santos, David P., Blanz, Judith +8 more·2017·Science
Cited by (875)
Items 401–500 of 875
- Dysregulation of mitochondrial α-ketoglutarate dehydrogenase leads to elevated lipid peroxidation in CHCHD2-linked Parkinson’s disease modelsGe Gao, Yongyong Shi, Han‐Xiang Deng, Dimitri Krainc · 2025 · Nature Communications
- Advances in research on mitochondrial dysfunction in neurodegenerative diseasesYao Zhang, Xiaowen Li, Yuan Zhang, Xing Li · 2025 · Journal of Neurology
- Proteome-Wide Profiling of Cellular Targets Modified by Dopamine Metabolites Using a Bio-Orthogonally Functionalized CatecholamineAlexander K. Hurben, Luke N. Erber, Natalia Y. Tretyakova, Todd M. Doran · 2021 · ACS Chemical Biology
- Antiparkinsonian effects of polyphenols: A narrative review with a focus on the modulation of the gut-brain axisWei Zhang, Xiaoyu Dong, Rui Huang · 2023 · Pharmacological Research
- Toxic interactions between dopamine, α-synuclein, monoamine oxidase, and genes in mitochondria of Parkinson’s diseaseMakoto Naoi, Wakako Maruyama, Masayo Shamoto‐Nagai, Peter Franz Riederer · 2024 · Journal of Neural Transmission
- Stem cells: A path towards improved epilepsy therapiesZane R. Lybrand, Sonal Goswami, Jenny Hsieh · 2019 · Neuropharmacology
- Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synucleinLandeck, Natalie, Strathearn, Katherine E., Ysselstein, Daniel, Buck, Kerstin, Dutta, Sayan, Banerjee, Siddhartha, Lv, Zhengjian, Hulleman, John D., Hindupur, Jagadish, Lin, Li-Kai et al. · 2020 · Molecular Neurodegeneration
- Advances in Fluorescence Techniques for the Detection of Hydroxyl Radicals near DNA and Within Organelles and MembranesEleanor Clare Ransdell-Green, Janina Baranowska‐Kortylewicz, Dong Wang · 2025 · Antioxidants
- Alpha-Synuclein drives NURR1 and NLRP3 Inflammasome dysregulation in Parkinson's disease: From pathogenesis to potential therapeutic strategiesAhmed M Abdelaziz · 2025 · International Immunopharmacology
- Neuromelanin and selective neuronal vulnerability to Parkinson’s diseaseAnastasia Filimontseva, YuHong Fu, Miquel Vila, Glenda Margaret Halliday · 2025 · Trends in Neurosciences
- Structural Features and Toxicity of α-Synuclein Oligomers Grown in the Presence of DOPACLuana Palazzi, Benedetta Fongaro, Manuela Leri, Laura Acquasaliente, Massimo Stefani, Monica Bucciantini, Patrizia Polverino de Laureto · 2021 · International Journal of Molecular Sciences
- The Zinc Ionophore Clioquinol Reduces Parkinson’s Disease Patient-Derived Brain Extracts-Induced NeurodegenerationMargaux Teil, Évelyne Doudnikoff, Marie-Laure Thiolat, Sylvain Bohic, Erwan Bézard, Benjamin Dehay · 2022 · Molecular Neurobiology
- The evolution of organellar calcium mapping technologiesMatthew A. Zajac, Souvik Modi, Yamuna Krishnan · 2022 · Cell Calcium
- Natural variation in age-related dopamine neuron degeneration is glutathione dependent and linked to life spanColin R. Coleman, Judit Pallos, Alicia Arreola-Bustos, Lu Wang, Daniel Raftery, Daniel Promislow, Ian Martin · 2024 · Proceedings of the National Academy of Sciences
- Enhancing the Activity of Glucocerebrosidase as a Treatment for Parkinson DiseaseElisa Menozzi, Anthony H.V. Schapira · 2020 · CNS Drugs
- Murine Models of Lysosomal Storage Diseases Exhibit Differences in Brain Protein Aggregation and NeuroinflammationJennifer Leigh Clarke, Can Kayatekin, Catherine Viel, Lamya S. Shihabuddin, S. Pablo Sardi · 2021 · Biomedicines
- Gangliosides as Biomarkers of Human Brain Diseases: Trends in Discovery and Characterization by High-Performance Mass SpectrometryMirela Sârbu, Raluca Ică, Alina Diana Zamfir · 2022 · International Journal of Molecular Sciences
- In situ fluorescence imaging reveals that mitochondrial H 2 O 2 mediates lysosomal dysfunction in depressionXin Wang, Qi Ding, Ying Tian, Wei Wu, Feida Che, Ping Li, Wen Zhang, Wei Zhang, Bo Tang · 2022 · Chemical Communications
- Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neuronsAaron M. Earley, Lena F. Burbulla, Dimitri Krainc, Rajeshwar B. Awatramani · 2021 · Scientific Reports
- DJ-1 protects proteins from acylation by catalyzing the hydrolysis of highly reactive cyclic 3-phosphoglyceric anhydrideAizhan Akhmadi, Adilkhan Yeskendir, Nelly Dey, Arman Mussakhmetov, Zariat Shatkenova, Arman Kulyyassov, Anna Y. Andreeva, Darkhan Utepbergenov · 2024 · Nature Communications
- The “Sick-but-not-Dead” Phenomenon Applied to Catecholamine Deficiency in Neurodegenerative DiseasesDavid S. Goldstein · 2020 · Seminars in Neurology
- Current State-of-the-Art and Unresolved Problems in Using Human Induced Pluripotent Stem Cell-Derived Dopamine Neurons for Parkinson’s Disease Drug DevelopmentStanislav A. Antonov, Ekaterina V. Novosadova · 2021 · International Journal of Molecular Sciences
- Basal Ganglia Atrophy as a Marker for Prodromal X‐Linked Dystonia‐ParkinsonismHenrike Hanßen, Cid Czarina E. Diesta, Marcus Heldmann, Jackson Dy, Jeffrey Tantianpact, Julia Steinhardt, Rosanna Sauza, Hans T. S. Manalo, Andreas Sprenger, Charles Jourdan Reyes et al. · 2023 · Annals of Neurology
- Shifting the trajectory of therapeutic development for neurological and psychiatric disordersDimitri Krainc, William J. Martin, Bradford H. Casey, Frances E. Jensen, Sarah A. Tishkoff, William Z. Potter, Steven E. Hyman · 2023 · Science Translational Medicine
- Targeted reversal of iron deposition by highly active manganese-doped carbon dots in MRI-guided treatment of Parkinson's diseaseHuihui Wang, Maolin Zhang, Dongchuan Chu, Xueping Huang, Yu Shi, Yi Yang Zhao, Hang Qu, Dandan Li, Zhuobin Xu, Xiaohong Wang et al. · 2025 · Carbon
- Commander complex regulates lysosomal function and is implicated in Parkinson’s disease riskGeorgia Minakaki, Nathaniel Safren, Bernabé I. Bustos, Steven J Lubbe, Niccolò Emanuele Mencacci, Dimitri Krainc · 2025 · Science
- Dissecting the non-neuronal cell contribution to Parkinson’s disease pathogenesis using induced pluripotent stem cellsPons-Espinal, Meritxell, Blasco-Agell, Lucas, Consiglio, Antonella · 2021 · Cellular and Molecular Life Sciences
- Mitochondrial Phenotypes in Parkinson’s Diseases—A Focus on Human iPSC-Derived Dopaminergic NeuronsLeonie M. Heger, Rachel M. Wise, J. Tabitha Hees, Angelika Bettina Harbauer, Lena F. Burbulla · 2021 · Cells
- Parkin as a Molecular Bridge Linking Alzheimer’s and Parkinson’s Diseases?Frédéric Checler, Cristine Alvès da Costa · 2022 · Biomolecules
- Recent Advances in the Treatment of Genetic Forms of Parkinson’s Disease: Hype or Hope?Francesco Cavallieri, Rubens Gisbert Cury, Thiago Gonçalves Guimarães, Valentina Fioravanti, Sara Grisanti, Jessica Rossi, Edoardo Monfrini, Marialuisa Zedde, Alessio Di Fonzo, Franco Valzania et al. · 2023 · Cells
- Insights into GBA Parkinson's disease pathology and therapy with induced pluripotent stem cell model systemsPascale Baden, Cong Yu, Michela Deleidi · 2019 · Neurobiology of Disease
- Shared Pathological Mechanisms Between Diabetes Mellitus and Neurodegenerative DiseasesAva Nasrolahi, Javad Mahmoudi, Ali Noori-Zadeh, Karimeh Haghani, Salar Bakhtiyari, Shahram Darabi · 2019 · Current Pharmacology Reports
- MicroRNA-93 Blocks Signal Transducers and Activator of Transcription 3 to Reduce Neuronal Damage in Parkinson’s DiseaseXiufeng Wang, Zhijun Liu, Fang Wang · 2021 · Neurochemical Research
- A molecular framework for autistic experiences: Mitochondrial allostatic load as a mediator between autism and psychopathologyCaitlyn Mahony, Colleen O’Ryan · 2022 · Frontiers in Psychiatry
- Luminol electrochemiluminescence by combining cathodic reduction and anodic oxidation at regenerable cobalt phthalocyanine modified carbon paste electrode for dopamine detectionZhiyong Dong, Fangxin Du, Tesfaye Hailemariam Barkae, Kaixiang Ji, Fangshuo Liu, Dmytro Viktorovych Snizhko, Yiran Guan, Guobao Xu · 2022 · Electrochimica Acta
- Calcineurin inhibition protects against dopamine toxicity and attenuates behavioral decline in a Parkinson’s disease modelRupsha Mondal, Chayan Banerjee, Sumangal Nandy, Moumita Roy, Joy Chakraborty · 2023 · Cell & Bioscience
- Advancements in Genetic and Biochemical Insights: Unraveling the Etiopathogenesis of Neurodegeneration in Parkinson’s DiseaseYashumati Ratan, Aishwarya Rajput, Ashutosh Pareek, Aaushi Pareek, Vivek Kumar Jain, Sonia Sonia, Zeba Farooqui, Ranjeet Kaur, Gurjit Singh · 2024 · Biomolecules
- Levodopa Impairs the Energy Metabolism of the Basal Ganglia In VivoJannik Prasuhn, Tanja Schiefen, Theresia Güber, Julia Henkel, Jan Christoph Uter, Julia Steinhardt, Britta Wilms, Norbert Brüggemann · 2024 · Annals of Neurology
- Altered regulation of serum lysosomal acid hydrolase activities in Parkinson's disease: A potential peripheral biomarker?Yoshiki Niimi, Shinji Ito, Yasuaki Mizutani, Kenichiro Murate, Sayuri Shima, Akihiro Ueda, Wataru Satake, Nobutaka Hattori, Tatsushi Toda, Tatsuro Mutoh · 2018 · Parkinsonism & Related Disorders
- Estimates of Intracellular Dopamine in Parkinson’s Disease: A Systematic Review and Meta-AnalysisJonathan Sackner‐Bernstein · 2021 · Journal of Parkinson s Disease
- Amyloid-mimicking toxic nanofibers generated via self-assembly of dopamineKailash Prasad Prajapati, Bibin Gnanadhason Anand, Masihuzzaman Ansari, Mayur Temgire, Ashu Bhan Tiku, Karunakar Kar · 2022 · Nanoscale
- MicroRNAs Modulating Neuroinflammation in Parkinson's diseaseMohamed Jamal Saadh, Faris Anad Muhammad, Anamika Singh, Mohammed Ahmed Mustafa, Rafil Adnan Hussein Al Zuhairi, Pallavi Ghildiyal, Ghassan Mudher Hashim, Fahad Alsaikhan, Shayan Khalilollah, Reza Akhavan‐Sigari · 2024 · Inflammation
- Innovative Applications and Perspectives of Surface‐Enhanced Raman Spectroscopy Technology in BiomedicineLei Xu, Yujiao Xie, Aochi Liu, Liting Xie, Xinyu Miao, Zhiwei Hou, Lingchao Xiang, Tianan Jiang, Aiguo Wu, Jie Lin · 2024 · Small
- Are oligodendrocytes bystanders or drivers of Parkinson’s disease pathology?José Maria Salazar Campos, L. Burbulla, S. Jäkel · 2025 · PLoS Biology
- Novel strategies targeting mitochondria-lysosome contact sites for the treatment of neurological diseasesYinyin Xie, Wenlin Sun, Aoya Han, Xinru Zhou, Shijie Zhang, Chuchu Shen, Yi Xie, Cui Wang, Nanchang Xie · 2025 · Frontiers in Molecular Neuroscience
- CCL21-CCR7 blockade prevents neuroinflammation and degeneration in Parkinson’s disease modelsFelipe Saceanu Leser, Flavio de Souza Júnyor, Iohanna Bianca Pagnoncelli, Anna Beatriz Temoteo Delgado, Isabelle Medeiros, Ana Clara Campanelli Nóbrega, Brenda da Silva Andrade, Maiara N. Lima, Nicolas Raposo Silva, Laurent Jacob et al. · 2025 · Journal of Neuroinflammation
- Motor and non-motor fluctuations in Parkinson’s disease: the knowns and unknowns of current therapeutic approachesMartin Regensburger, Ilona Csóti, Wolfgang H. Jost, Zacharias Kohl, Stefan Lorenzl, David José Pedrosa, Paul Lingor · 2025 · Journal of Neural Transmission
- Adaptations in Mitochondrial Function Induced by Exercise: A Therapeutic Route for Treatment-Resistant DepressionArnulfo Ramos‐Jiménez, Mariazel Rubio-Valles, Javier A. Ramos-Hernández, Everardo González-Rodríguez, Verónica Moreno-Brito · 2025 · International Journal of Molecular Sciences
- In vivo overexpression of synaptogyrin‐3 promotes striatal synaptic dopamine uptake in LRRK2 R1441G mutant mouse model of Parkinson's diseasePhilip Wing‐Lok Ho, Lingfei Li, Hui‐Fang Liu, Zoe Yuen-Kiu Choi, Eunice Eun Seo Chang, Shirley Yin‐Yu Pang, Yasine Malki, Chi-Ting Leung, Michelle Hiu-Wai Kung, David Boyer Ramsden et al. · 2023 · Brain and Behavior
- Linking Mitochondrial Dysfunction, Neurotransmitter, and Neural Network Abnormalities and Mania: Elucidating Neurobiological Mechanisms of the Therapeutic Effect of the Ketogenic Diet in Bipolar DisorderZachary Freyberg, Ana C. Andreazza, Colleen A. McClung, Mary Louise Phillips · 2024 · Biological Psychiatry Cognitive Neuroscience and Neuroimaging
- Longitudinal neuromelanin changes in prodromal and early Parkinson’s disease in humans and rat modelJ. Pérot, Anthony Ruze, Rahul Gaurav, Sana Rebbah, Capucine Cadin, Arnaud Le Troter, Lucas Soustelle, Laura Mouton, Romain Valabrègue, Annabelle Parent et al. · 2025 · Brain Communications
- Genome-Edited, TH-expressing Neuroblastoma Cells as a Disease Model for Dopamine-Related Disorders: A Proof-of-Concept Study on DJ-1-deficient ParkinsonismJannik Prasuhn, Christoph U. Mårtensson, Victor Krajka, Christine Klein, Aleksandar Raković · 2018 · Frontiers in Cellular Neuroscience
- Effects of Acute Ethanol Administration on Brain Oxidative Status: The Role of AcetaldehydePablo Baliño, Ricard Romero‐Cano, Juan V. Sanchez‐Andrés, Victoria Valls, Carlos González Aragón, María Muriach · 2019 · Alcoholism Clinical and Experimental Research
- Analysis of α-synuclein levels related to LRRK2 kinase activity: from substantia nigra to urine of patients with Parkinson’s diseaseDaleum Nam, Ami Kim, Sun Jung Han, Sung-Ik Lee, Sung‐Hye Park, Wongi Seol, Ilhong Son, Dong Hwan Ho · 2021 · Animal Cells and Systems
- Patient-Specific iPSCs-Based Models of Neurodegenerative Diseases: Focus on Aberrant Calcium SignalingDmitriy A. Grekhnev, Elena V. Kaznacheyeva, Vladimir A. Vigont · 2022 · International Journal of Molecular Sciences
- Are we listening to everything the PARK genes are telling us?Deanna L. Benson, George W. Huntley · 2019 · The Journal of Comparative Neurology
- AMPK mediates the neurotoxicity of iron oxide nanoparticles retained in mitochondria or lysosomesHui Huang, Mengxue Zhou, Lifo Ruan, Dongqing Wang, Huiru Lu, Jiayu Zhang, Jun Chen, Yi Hu, Zhifang Chai · 2019 · Metallomics
- Communications Among Neurocytes in Parkinson's Disease Regulated by Differential Metabolism and Blood‐Brain Barrier Traversing of Chiral Gold Cluster‐MOF Integrated NanoparticlesJunyang Chen, Gaoxiang Xu, Runpu Shen, Jianzhong Xu, Congcong Lu, Xin Li, Qi Feng, Qing Li · 2025 · Advanced Science
- Pathological Mechanisms and Clinical Aspects of GBA1 Mutation-Associated Parkinson’s DiseaseThomas B. Stoker, Kelli Torsney, Roger A. Barker · 2018 · Codon Publications eBooks
- Human Induced Pluripotent Stem Cell Phenotyping and Preclinical Modeling of Familial Parkinson’s DiseaseJeffrey J. Kim, Etienne W. Daadi, Thomas T Oh, Elyas S. Daadi, Marcel M. Daadi · 2022 · Genes
- Parkin coregulates glutathione metabolism in adult mammalian brainDaniel N. El Kodsi, Jacqueline M. Tokarew, Rajib Sengupta, Nathalie A. Lengacher, Ajanta Chatterji, Angela Nguyen, Heather Boston, Qiubo Jiang, Carina Palmberg, Chantal A. Pileggi et al. · 2023 · Acta Neuropathologica Communications
- Aging and Parkinson’s disease: a complex interplay of vulnerable neurons, the immune system and the blood-brain barrierJonas Bendig, Anika K. Frank, Heinz Reichmann · 2024 · Ageing and Neurodegenerative Diseases
- A transient post-translational modification of active site cysteine alters binding properties of the parkinsonism protein DJ-1Arman Mussakhmetov, I.A. Shumilin, Raushan Nugmanova, Ivan G. Shabalin, Timur Baizhumanov, Daulet Toibazar, Bekbolat Khassenov, Wladek Minor, Darkhan Utepbergenov · 2018 · Biochemical and Biophysical Research Communications
- Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson’s diseaseElena Coccia, Tim Ahfeldt · 2021 · Stem Cell Research & Therapy
- Stress-induced phospho-ubiquitin formation causes parkin degradationLyudmila Kovalchuke, Eugene V. Mosharov, Oren A. Levy, Lloyd A. Greene · 2019 · Scientific Reports
- The Parkinson’s disease DJ-1 / PARK7 gene controls peripheral neuronal excitability and painful neuropathySang Hoon Lee, Raquel Tonello, Kihwan Lee, Jueun Roh, Arthur Silveira Prudente, Yong Ho Kim, Chul‐Kyu Park, Temugin Berta · 2024 · Brain
- TMEM175 does not function as a proton-selective ion channel to prevent lysosomal over-acidificationErika A. Riederer, Vedrana Mikušević, Tuoxian Tang, Lillian Martin, Joseph A. Mindell, Dejian Ren · 2025 · The Journal of Cell Biology
- iPSC‐based modeling of THD recapitulates disease phenotypes and reveals neuronal malformationAlba Tristán‐Noguero, Irene Fernández‐Carasa, Carles Calatayud, Cristina Bermejo‐Casadesús, Meritxell Pons‐Espinal, Arianna Colini Baldeschi, Leticia Campa, Francesc Artigas, Analı́a A Bortolozzi, Rosario Domingo Jiménez et al. · 2023 · EMBO Molecular Medicine
- Targeting the Cysteine Redox Proteome in Parkinson’s Disease: The Role of Glutathione Precursors and BeyondMarcos Martı́nez · 2023 · Antioxidants
- Dopamine‑iron homeostasis interaction rescues mitochondrial fitness in Parkinson's diseaseChiara Buoso, Markus Seifert, Martin Lang, Corey M. Griffith, Begoña Talavera Andújar, Maria Paulina Castelo Rueda, Christine Fischer, Carolina Doerrier, Heribert Talasz, Alessandra Zanon et al. · 2024 · Neurobiology of Disease
- Programmed cell death and melatonin: A comprehensive reviewMahdi Rafiyan, Russel Joseph Reiter, Sayyed Mehdi Rasooli Manesh, Reza Asemi, Mehran Sharifi, Sotoudeh Mohammadi, Mohammad Alì Mansournia, Zatollah Asemi · 2024 · Functional & Integrative Genomics
- Reactive oxygen species and neurodegenerative diseases: insights into nanozyme therapeuticsLuo Wang, Feixiang Chen, Cuiling Zhang, Yuen Yee Cheng, Wenbo Bu, Yanyan Liu · 2024 · MedMat.
- TRH Analog, Taltirelin Improves Motor Function of Hemi-PD Rats Without Inducing Dyskinesia via Sustained Dopamine Stimulating EffectCong Zheng, Guiqin Chen, Yang Tan, Weiqi Zeng, Qiwei Peng, Ji Wang, Chi Cheng, Xiaoman Yang, Shuke Nie, Yan Xu et al. · 2018 · Frontiers in Cellular Neuroscience
- Hispidin in the Medicinal Fungus Protects Dopaminergic Neurons from JNK Activation-Regulated Mitochondrial-Dependent Apoptosis in an MPP+-Induced In Vitro Model of Parkinson’s DiseaseMei-Chou Lai, Wayne-Young Liu, Shorong‐Shii Liou, I-Min Liu · 2023 · Nutrients
- Construction of chemoreactive heterogeneous nanofibers through strategic coassembly of different proteinsM. Ansari, Kailash Prasad Prajapati, Bibin Gnanadhason Anand, P. Chaudhuri, S. Mittal, Karunakar Kar · 2023 · Materials Today Nano
- Pluripotent stem cells for neurodegenerative disease modeling: an expert view on their value to drug discoveryShi-Dong Chen, Hong‐Qi Li, Mei Cui, Qiang Dong, Jin‐Tai Yu · 2020 · Expert Opinion on Drug Discovery
- Research models to study lewy body dementiaSuelen Lucio Boschen, Aarushi A. Mukerjee, Ayman H. Faroqi, Benjamin E. Rabichow, John Denis Fryer · 2025 · Molecular Neurodegeneration
- DJ-1/PARK7 in Parkinson’s disease: mechanisms of pathogenesis and therapeutic potentialWeicong Bao, Ying Ge, Juan Huang, Yuanyuan Li, Yong Luo, Nanqu Huang · 2025 · Neuroscience
- Neuroprotective effects of a novel peptide from Lignosus rhinocerotis against 6‐hydroxydopamine‐induced apoptosis in PC12 cells by inhibiting NF‐κB activationChuan Xiong, Zhu Yu, Qiang Luo, Chia‐Wei Phan, Yujie Huo, Ping Li, Qiang Li, Xin Jin, Wenli Huang · 2022 · Food Science & Nutrition
- Iron- and Neuromelanin-Weighted Neuroimaging to Study Mitochondrial Dysfunction in Patients with Parkinson’s DiseaseBenjamín Pizarro-Galleguillos, Liesa Kunert, Norbert Brüggemann, Jannik Prasuhn · 2022 · International Journal of Molecular Sciences
- Dopamine modification of glycolytic enzymes impairs glycolysis: possible implications for Parkinson’s diseaseBing Chen, Qian Zhang, Xiaoru Zhong, Xinwei Zhang, Xin Liu, Hongyang Wang, Fan Yang, Jingjing Zhang, Jingnan Huang, Yin‐Kwan Wong et al. · 2024 · Cell Communication and Signaling
- The Contribution of Type 2 Diabetes to Parkinson’s Disease AetiologySamo Ribarič · 2024 · International Journal of Molecular Sciences
- Determination of Dopamine Using 2-(4-Boronophenyl)quinoline-4-carboxylic Acids as Fluorescent ProbesHao Wang, Guiqian Fang, Kai Wang, Zhongyu Wu, Qingqiang Yao · 2018 · Analytical Letters
- Enhancement of anti-inflammatory effect of cattle bile by fermentation and its inhibition of neuroinflammation on microglia by inhibiting NLRP3 inflammasomeYuying Pei, Fafeng Cheng, Wěi Li, Qiaoyu Yu, Chongyang Ma, Yan Zou, Tian Xu, Shilin Liu, Shuang Zhang, Qingguo Wang · 2021 · Journal of Bioscience and Bioengineering
- Monoterpenoid Epoxidiol Ameliorates the Pathological Phenotypes of the Rotenone-Induced Parkinson’s Disease Model by Alleviating Mitochondrial DysfunctionYulia R. Aleksandrova, Kirill Chaprov, Alexandra V. Podturkina, Oleg V. Ardashov, Ekaterina Yu. Yandulova, Konstantin Petrovich Volcho, Nariman Faridovich Salakhutdinov, Маргарита Е. Неганова · 2023 · International Journal of Molecular Sciences
- Inhibition of EHMT1/2 rescues synaptic damage and motor impairment in a PD mouse modelZhixiong Zhang, Rui Wang, Hui Zhou, Dan Wu, Yifan Cao, Chuang Zhang, Hongyang Sun, Chenchen Mu, Zongbing Hao, Haigang Ren et al. · 2024 · Cellular and Molecular Life Sciences
- Preserved striatal innervation maintains motor function despite severe loss of nigral dopaminergic neuronsThomas Paß, Konrad M. Ricke, Pierre Hofmann, Roy Chowdhury, Yu Nie, Patrick Francis Chinnery, Heike Endepols, Bernd Neumaier, Andre Ferrer Carvalho, Lionel Rigoux et al. · 2024 · Brain
- Exploring the link between pyrethroids exposure and dopaminergic degeneration through morphometric, immunofluorescence, and in-silico approaches: the therapeutic role of chitosan-encapsulated curcumin nanoparticlesBadriyah Shadid Alotaibi, Amany Abdel-Rahman Mohamed, Yasmina M. Abd‐Elhakim, Ahmed Elsayed Noreldin, Moustafa Elhamouly, Tarek Khamis, Ali H. El‐Far, Manal E. Alosaimi, Naief A. Dahran, Leena S. Alqahtani et al. · 2024 · Frontiers in Pharmacology
- Diverse Functions of Parkin in Midbrain Dopaminergic NeuronsPingping Song, Dimitri Krainc · 2024 · Movement Disorders
- Mesenchymal stromal cells deliver H2S-enhanced Nrf2 via extracellular vesicles to mediate mitochondrial homeostasis for repairing hypoxia-ischemia brain damageChengcheng Gai, Tingting Li, Yijing Zhao, Yahong Cheng, Yan Y. Song, Qian Luo, Dexiang Liu, Zhen Wang · 2024 · Free Radical Biology and Medicine
- Too much for your own good: Excessive dopamine damages neurons and contributes to Parkinson's diseaseAnna Masato, Luigi Bubacco, Elisa Greggio · 2021 · Journal of Neurochemistry
- Direct targeting of wild-type glucocerebrosidase by antipsychotic quetiapine improves pathogenic phenotypes in Parkinson’s disease modelsLena F. Burbulla, Jianbin Zheng, Pingping Song, Weilan Jiang, Michaela Johnson, Patrik Brundin, Dimitri Krainc · 2021 · JCI Insight
- DJ‐1 depletion prevents immunoaging in T‐cell compartmentsNi Zeng, Christophe Capelle, Alexandre Baron, Takumi Kobayashi, Severine Cire, Vera Tslaf, Cathy Leonard, Djalil Coowar, Haruhiko Koseki, Astrid M Westendorf et al. · 2022 · EMBO Reports
- Neuroprotective microRNA-381 Binds to Repressed Early Growth Response 1 (EGR1) and Alleviates Oxidative Stress Injury in Parkinson’s DiseaseShaozhen Guo, Yuting Gao, Yuwei Zhao · 2023 · ACS Chemical Neuroscience
- A SERS Composite Hydrogel Device for Point-of-Care Analysis of Neurotransmitter in Whole BloodLei Wu, Xuefeng Liu, Shenfei Zong, Zhuyuan Wang, Yiping Cui · 2023 · Biosensors
- Pre-aggregation kinetics and intermediates of α-synuclein monitored by the ESIPT probe 7MFEJonathan A. Fauerbach, Thomas M. Jovin · 2017 · European Biophysics Journal
- Therapeutic Potential of Baicalein in Parkinson’s Disease: Focus on Inhibition of α-Synuclein Oligomerization and AggregationHayate Javed, Shreesh Kumar Ojha · 2019 · IntechOpen eBooks
- Mitochondria-targeted aggregation-induced emission active near infrared fluorescent probe for real-time imagingYanjing Dong, Zikang Chen, Meirong Hou, Qi Li, Chenggong Yan, Xiaodan Lü, Ruiyuan Liu, Yikai Xu · 2019 · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
- Schisandra chinensis water extract protects ethanol‐induced neurotoxicity in Caenorhabditis elegansZhongqin Wu, Ke Li, Xing Tian, Ming‐Xi Zhou, Zongjun Li · 2020 · Journal of Food Biochemistry
- Domain-Independent Inhibition of CBP/p300 Attenuates α-Synuclein AggregationIrena Hlushchuk, Heikki J Ruskoaho, Andrii Domanskyi, Mikko Airavaara, Mika J. Välimäki · 2021 · ACS Chemical Neuroscience