Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease
Burbulla, Lena F., Song, Pingping, Mazzulli, Joseph R., Zampese, Enrico, Wong, Yvette C., Jeon, Sohee, Santos, David P., Blanz, Judith +8 more·2017·Science
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- Selective neurodegeneration in patients with parkinson’s diseaseFurkat A. Yusupov, M.Sh. Abdykadyrov · 2026 · S S Korsakov Journal of Neurology and Psychiatry
- The role of mitochondria-associated membranes in tumorigenesisYaqin Zhu, Guoyi Tang, Muya Tang, Baozhen Zhou, Jing Xu, Xiaoli Ma, Ziyu Li, Guichun Liu, Yu Han · 2026 · Discover Oncology
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- Aberrant immunomodulatory signature in β-propeller protein-associated neurodegeneration patient iPSC-derived microgliaGamze Özata, Rachel M. Wise, Aida Cardona-Alberich, Naiyareen F. Mayeen, Stephan A. Müller, Stefan F. Lichtenthaler, Luigi Zecca, Lena F. Burbulla · 2026 · Scientific Reports
- A druggable link between the angiotensin receptor 1 and α-synuclein pathology revealed in scalable human cellular models of Parkinson’s diseaseMathieu Daynac, Vincent Mouilleau, Annabel Menendez, Yuxi Liu, Xiaoyu Yang, Yin Shen, Su Guo · 2026 · Molecular Neurodegeneration Advances
- Subacute Exposure to Macrocyclic Lactone Insecticides Induces Parkinson’s Disease-like Motor Deficits and Neuropathology in MiceJinjing Xiao, Yuying Liu, Shujie Wang, Kaijie Dai, Zhuang Ye, Su Shi, Zengxue Liu, Haiqun Cao, Yanhong Shi · 2026 · Environmental Science & Technology
- Astrocytes orchestrate neuroprotection and pathogenesis via bidirectional neuronal interactions in Parkinson’s diseaseYifan Li, Qiang Li, Yemin Wang, Xuejing Wang, Guangfu Di, Meng Niu, Zhiliang Xu, Yanjiao Huang · 2026 · Journal of Physiology and Biochemistry
- Lysosomal dysfunction in neurodegenerative diseaseSarah M. Brooker, Robert Coukos, Dimitri Krainc · 2026 · Nature Reviews Neurology
- Aging with Parkinson’s DiseaseJoe R. Nocera, Keith McGregor · 2018 · Handbooks in health, work, and disability
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- Ca2+-regulated enzymes calpain and calcineurin in neurodegenerative processes and prospects for neuroprotective pharmacotherapyVarduhi H. Knaryan, F. P. Sarukhanyan · 2023 · S S Korsakov Journal of Neurology and Psychiatry
- ProSE-Pero: Peroxisomal Protein Localization Identification Model Based on Self-Supervised Multi-Task Language Pre-Training ModelJianan Sui, Jiazi Chen, Yuehui Chen, Naoki Iwamori, Jin Sun · 2023 · Frontiers in Bioscience-Landmark
- Meta-analysis of the association of prosaposin polymorphisms rs4747203 and rs885828 with risk of Parkinson’s diseaseLiuhui Zhu, Xinyue Zhang, Ying Guan, Yongyun Zhu, Qian Zhou, Bin Liu, Hui Jun Ren, Xinglong Yang · 2024 · Acta Neurologica Belgica
- Protocol to investigate Parkinson’s patient-derived dopaminergic neurons by live-cell microscopy and oxidized dopamine assaysPingping Song, Dimitri Krainc · 2024 · STAR Protocols
- Analysis of dopaminergic neuron-specific mitochondrial morphology and function using tyrosine hydroxylase reporter iPSC linesMutsumi Yokota · 2024 · Anatomical Science International
- Dopamine oxidation mediates a time‐dependent pathological cascade in Parkinson's diseaseLeonora Kulikovskaja, Philip Seibler · 2017 · Movement Disorders
- Extra-virgin Olive Oil, the Mediterranean Diet, and Neurodegenerative DiseasesAntonio Capurso, Gaetano Crepaldi, Cristiano A. Capurso · 2018 · Practical issues in geriatrics
- MITOCHONDRIAL DYSFUNCTION AND OXIDATIVE LESIONS IN RAT BRAIN UNDER MODELING OF PARKINSON’S LIKE SYNDROME: CORRECTIVE ACTION OF CAPICORMan'kovs'ka Im, Olga O. Gonchar, VI Nosar, K. V. Rozova, Larisa. V. Bratus, Evgenia E. Kolesnikova, Yu. V. Putiy, Karaban' In · 2018 · Fìzìologìčnij žurnal
- Monoamine Oxidase Inhibitor (MAO-I)-Mediated Neuroprotection for Treating Parkinson’s DiseaseToshiharu Nagatsu, Akira Nakashima · 2019 · Springer eBooks
- Progress in generating iPSC-derived dopaminergic neurons as accurate models of neurodegenerative diseaseRichard Sam, Tae‐Un Han, Ellen Sidransky, Yu Chen · 2021 · Elsevier eBooks
- Features of the mitochondrial dysfunction development in Parkinson’s disease, possibilities of drug correction for ultrastructural disordersE. V. Rozova, Olga O. Gonchar, Karaban' In, Nina Karasevych, Maryna Khodakovska, N.O. Melnik · 2024 · INTERNATIONAL NEUROLOGICAL JOURNAL
- Dopamine and Serotonin Metabolism in Parkinsonian ModelsCarmen De La Fuente Barrigon · 2018 · UCL Discovery (University College London)
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- Novel Therapeutic Targets and Biomarkers for the Treatment of Progressive Supranuclear PalsyImogen Tyer, Alison Hill · 2020 · Preprints.org
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- Mitochondrial fitness influences neuronal excitability of dopaminergic neurons from patients with idiopathic form of Parkinson’s diseasePaula Chlebanowska, Agata Szlaga, Anna Tejchman, Marta Kot, Paweł S. Konieczny, Klaudia Skrzypek, Agata Muszyńska, Małgorzata Katarzyna Sobocińska, Krystyna Golebiowska, Paweł P. Łabaj et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- GBA1 mutations alter neuronal firing and structure, regulating VGLUT2 and CRYAB in dopamine neuronsEva Rodríguez‐Traver, Luz M. Suárez, Carlos Crespo, Irene González-Burgos, Rebeca Vecino, Juan Camilo Jurado-Coronel, María Galán, Marta González-González, Rosario Moratalla, Carlos Vicario‐Abejón · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Calcineurin-mediated regulation of growth-associated protein 43 is essential for neurite and synapse formation and protects against α-synuclein-induced degenerationSofia Zaichick, Ekaterina A. Grebenik, Gabriela Caraveo · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Scalable Human Cellular Models of Parkinson’s Disease Reveal A Druggable Link Between the Angiotensin Receptor 1 and α-Synuclein PathologyMathieu Daynac, Vincent Mouilleau, Yuxi Liu, Xiaoyu Yang, Yin Shen, Su Guo · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Parkinsonism Reversal and Dopaminergic Resilience: Lessons from a Rotenone-induced Parkinson’s Disease ModelPrince Joshi, Fan Fan, Xuelin Lou · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Papers of note in Science 357 (6357)Annalisa M. VanHook · 2017 · Science Signaling
- High priority publications on Parkinson's disease in 2017Tanya Simuni, Dimitri Krainc · 2017 · The Lancet Neurology
- Natural and Synthetic GHSR1a Agonists as Neuroprotective Agents in Models of Parkinson's diseaseDaniel J. Rees · 2017
- Lysosomal and mitochondrial crosstalk: the role of lysosomal signaling on mitochondrial biogenesis and functionKing Faisal Yambire · 2018
- Pallidopyramidal Syndrome and Hereditary Spastic Paraplegia common features and diagnostic approach and therapeutic considerationsCorneliu Angelo Bulboacă, Mihai Blidaru, Dana Gabriela Festila, Paul-Mihai Boarescu, Ioana Stănescu · 2019 · Balneo Research Journal
- Investigating early functional alteration in a human iPSC-based model of Parkinson’s DiseaseGiulia Carola · 2019 · Dipòsit Digital de la Universitat de Barcelona (Universitat de Barcelona)
- Investigation into the effect of LRRK2-Rab10 protein interactions on the Proboscis Extension Response of the fruit fly Drosophila melanogasterLaura Covill · 2018 · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)
- Development of analytical tools to enrich and identify protein dopaminylationEmily Jane Myers · 2020 · ResearchWorks at the University of Washington (University of Washington)
- Modernized Divination into FerroptosisRahul R Jain · 2020 · International Journal for Research in Applied Science and Engineering Technology
- Chemical biology: a toolbox to unlock neurochemical epigenetics?Dennis Özcelik · 2020 · Neural Regeneration Research
- Parkinson's disease: Genetic-driven therapeutic approachesS. Pablo Sardi, Marco A. S. Baptista · 2020 · Elsevier eBooks
- Pharmacocorrection of mitochondrial dysfunction and energy imbalance of substantia nigra neurons in experimental Parkinson's disease in ratsVolodymyr Maramukha · 2020 · Journal of Education Health and Sport
- IS THERE AN ORGAN-SPECIFIC EXPRESSION OF CANDIDATE GENES (DJ1, PINK1) IN TISSUES OF THE ORGANISM UNDER EXPERIMENTAL PARKINSONISM AND ITS PATHOGENETIC THERAPY?Rozova Kateryna Vsevolodovna, Yu. V. Putiy · 2021 · Science Review
- The role of oxidative stress and the underlying biological pathways in the pathogenesis of Parkinson’s DiseaseBela Peethambaran, Chelsea Leonce, Amrut Patel · 2021 · International Journal of Complementary & Alternative Medicine
- Characterisation of the ghrelinergic system in human models of neurodegenerative diseasesMaria Carla Carisi · 2021
- Targeting Catecholamines to Develop New Drugs for Attention Deficit Hyperactivity DisorderSung‐Cherl Jung, Chang-Hwan Cho, Hye‐Ji Kim, Eun‐A Ko, Min-Woo Ha, Oh-Bin Kwon · 2021 · Journal of Medicine and Life Science
- Mitochondrial dysfunction and energy changes of black-substance neurons in experimental parkinson's disease in rats and mothorsN. M. Buchakchyiska, Igor F. Belenichev, Volodymyr Maramukha · 2021 · Modern medical technology
- Spatiotemporally Mapping Thermodynamics of Lysosomes and Mitochondria using Cascade Organelle-Targeting Upconversion NanoparticlesXiangjun Di, Qian Peter Su, Dejiang Wang, Yongtao Liu, Mahnaz Maddahfar, Jiajia Zhou, Dayong Jin · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Faculty Opinions recommendation of Mitochondrial Dysfunction Combined with High Calcium Load Leads to Impaired Antioxidant Defense Underlying the Selective Loss of Nigral Dopaminergic Neurons.Siegfried Hekimi, Alycia Noë · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
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- Tetramethylpyrazine nitrone exerts neuroprotection via PGC-1α/Nrf2 activation and α-synuclein clearance in Parkinson’s disease modelsBaojian Guo, Chengyou Zheng, Jie Cao, Shangming Li, Fangcheng Luo, Xiaoling Qiu, Kun Zhang, Wei Cai, Haitao Li, Ying Wang et al. · 2020
- The zinc ionophore clioquinol reduces Parkinson’s disease patient-derived brain extracts-induced neurodegenerationMargaux Teil, Évelyne Doudnikoff, Marie-Laure Thiolat, Sylvain Bohic, Erwan Bézard, Benjamin Dehay · 2022 · Research Square
- Patient-derived cells – an irreplaceable tool for research of reduced penetrance in movement disordersPhilip Seibler, Aleksandar Raković · 2022 · Medizinische Genetik
- PathogenesisRoger L. Albin · 2022 · Oxford University Press eBooks
- Ankylosing Spondylitis Complicated with Parkinson’s Disease: A Case Report and Literature Review雪梅 周 · 2023 · Advances in Clinical Medicine
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- Mitochondrial Dysfunction and Parkinson’s Disease洋 刘 · 2023 · Advances in Clinical Medicine
- Sterol Biomarker Discovery In Neurodegenerative DiseasesManuela Pacciarini · 2023
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- Copy number variations of proteins associated with neurodegenerative diseases and rare neurological disordersZhangzhong Yang, Peng Lei · 2024 · Scientia Sinica Vitae
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