Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation
Moda-Sava, R. N., Murdock, M. H., Parekh, P. K., Fetcho, R. N., Huang, B. S., Huynh, T. N., Witztum, J., Shaver, D. C., Rosenthal, D. L., Alway, E. J., Lopez, K., Meng, Y., Nellissen, L., Grosenick, L., Milner, T. A., Deisseroth, K., Bito, H., Kasai, H., Liston, C.·2019·Science
Cited by (644)
Items 601–644 of 644
- Ketamine’s Multifaceted Neuropharmacological and Neurobiological ActionsSamuel Kohtala, Iina Annala · 2025 · Neuromethods
- In Vivo Positron Emission Tomography Imaging of Presynaptic Density Reveals Stress-Associated Synaptic Deficits Related to Behavioral and Molecular Alterations in RatsRuth Asch, Nira Hernandez Martin, Rolando García-Milian, Krista Fowles, Ralph Dileone, Zhengxin Cai, Conor M. Liston, Irina Esterlis · 2025 · Biological Psychiatry Cognitive Neuroscience and Neuroimaging
- Dynamic Processes Induced by Ketamine and Their Potential for Augmented Treatment Strategies in Neuropsychiatric DisordersMeng Li, Zümrüt Duygu Şen, Lena Vera Danyeli, Nooshin Javaheripour, Martin Walter · 2025 · Neuromethods
- Human in vivo assessment of ketamine binding of the serotonin transporter—follow up at a higher doseG. Schlosser, Matej Murgaš, Godber Mathis Godbersen, Sabine Reichel, L. Silberbauer, Lukas Nics, Dietmar Winkler, Thomas Stimpfl, Markus Hacker, Siegfried F. Kasper et al. · 2025 · Frontiers in Neuroscience
- Ketamine strengthens synaptic inputs to the dorsal raphé to boost serotonergic activity: pivotal for rapid antidepressant-like effectsSoukaina Es-Safi, Céline Bourcier‐Lucas, Erika Abrial, Adeline Cathala, Thierry Lesté-Lasserre, Philippe De Deurwaerdère, Jean‐Michel Revest, Jean Mazella, Nasser Haddjeri, Guillaume Lucas · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Spatiotemporal remodeling in habenula marks the onset of depression-related phenotypesPatricia Molina, Denys Osypenko, Josep Garnica, Quentin Amossé, Farha Bouteldja, Léa Camelot, Sarah Mondoloni, Mauro Congiu, Claudia Kathe, Manuel Mameli · 2026 · Nature Neuroscience
- Serotonin receptor 4 in the ventral CA3 regulates agomelatine-induced anxiolytic-like behaviors.Xiang-Hu Liu, Muhammad Naveed, Xiao-Yun Hu, Lin-Lin Zhu, Fan Meng, Qi-Gang Zhou, Jing Zhang · 2025 · Acta Pharmacologica Sinica
- Additional file 1 of Loss of glucocorticoid receptor phosphorylation contributes to cognitive and neurocentric damages of the amyloid-β pathwayYann Dromard, Margarita Arango-Lievano, Amélie M. Borie, Maheva Dedin, Pierre Fontanaud, Joan Torrent, Michael J. Garabedian, Stephen D. Ginsberg, Freddy D. Jeanneteau · 2022 · Figshare
- Fast-acting antidepressants trigger presynaptic BDNF release and structural plasticity at mouse mossy fiber-CA3 synapsesIrem L Atasoy-Rodriguez, Kenneth W. Johnson, Kishan Patel, Haroon Arain, Syed Zaidi, Karl F. Herold, Teresa A. Milner, Hugh C. Hemmings, Jimcy Platholi · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- The Emerging Crisis in Non-Prescribed Ketamine Use: A Rapid Attenuation of Depression in Face of Abuse and “Chill-out” or Escapism DrugKai Uwe Lewandrowski, Kenneth Blum, Sergio Schmidt, Rossano Kepler Alvim Fiorelli, Mark S. Gold, Kavya Mohankumar, Alireza Sharafshah, Debasis Bagchi, Albert Pinhasov, Morgan P. Lorio et al. · 2026 · Substance Use & Misuse
- Age-related moderation of adjunctive psychotherapy and early life stress effects on depression symptom reductions following ketamine treatment: Initial insights from a large, naturalistic sampleRaquel Kosted, Alli Waddell, Ken Adolph, Gregory A. Fonzo · 2026 · Journal of Affective Disorders
- α 5 -GABA A allosteric modulation triggers and prolongs dopamine neuronal activity via AMPA receptorsAreebah Ahmed, Mostafa El Mansari, Pierre Blier · 2026 · Journal of Psychopharmacology
- MDMA enhances prefrontal plasticity and representational drift during fear extinctionNitzan Geva, Sarah J. Jefferson, Emi Krishnamurthy, Tanner L. Anderson, Jocelyne A. Rondeau, Patrick H. Wehrle, Axel Fogaça Rosado, Christopher Pittenger, John H. Krystal, Alfred P. Kaye · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- The role of transcription factor Neurod2 in cortex development and its implications in neurodevelopmental disordersKaren Runge · 2022 · theses.fr (ABES)
- Exploring the molecular determinants of behavioral changes induced by ketamine at the nanoscaleFloriane Uyttersprot · 2024 · theses.fr (ABES)
- Serotonergic psychedelics for Autism spectrum disorder: Neurobiological mechanisms and translational prospectsZhen Xuen Brandon Low · 2026 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Sex-Specific Reversal of Stress-Induced Depressogenic Behaviors by Inhibition of HMGB1, TLR4, and NF-κB SignalingAslıhan Bahadır‐Varol, Bengisu Solgun, Gülce Küreli, Emre Cem Esen, Emine Eren‐Koçak · 2026 · Molecular Neurobiology
- On the meaning of “plasticity” in neuroscience and mental health research and its relation to the action of psychedelic therapyRobin Lester Carhart-Harris, Richard J. Zeifman, Lorenzo Pasquini, Bijurika Nandi, Cyrus Rohani-Shukla, Shayam Suseelan, Pedro A. M. Mediano, Fernando C W Rosas, Christopher Timmermann, Hannes Kettner et al. · 2026 · Frontiers in Neuroscience
- This is IT: How accelerated intermittent theta burst stimulation relieves depression symptomsMorteza Salimi, Dhakshin Ramanathan · 2026 · Cell
- Chronic corticosterone biases conflict-related behavior and abolishes ketamine's anticonflict effect in miceNatsuko HitoraーImamura, Yuki Nishida, Koki Kawazoe, Kota Ono, Haruto Kumamoto, Yuki Kurauchi, Hiroshi Katsuki · 2026 · Journal of Pharmacological Sciences
- NMDA Receptor Mediated Mechanisms in the Post-Stroke Brain: From Physiology to PathologyHan Gong, Xiang-Zheng Wang, Dan Liu, Wei-Jin Liu, DU Xiaoxia, Jia‐Sheng Rao · 2026 · Biomolecules
- ЕВОЛЮЦІЯ КЕТАМІНУ: ВІД ДИСОЦІАТИВНОГО АНЕСТЕТИКА ДО ШВИДКОДІЮЧОГО АНТИДЕПРЕСАНТА ТА НОВИХ ТЕРАПЕВТИЧНИХ ГОРИЗОНТІВА. В. Чорномидз · 2026 · Здобутки клінічної і експериментальної медицини
- NMDA receptor–dependent structural plasticity links early life stress to persistent aggressionJessica T. Jacobs, Jacob C. Nordman · 2026 · Neurobiology of Stress
- Glucocorticoids-induced depressive-like behaviors in mice: oral ingestion of corticosterone or hydrocortisone − A comparative studyCarina Ioná de Oliveira Torres, Victor A.D. Holanda, Matheus Cardoso de Oliveira, Anne Nathalia de Sousa-Silva, Clarissa de Almeida Moura, Edilson Dantas da Silva Junior, Elaine Cristina Gavioli · 2026 · Neuroscience Letters
- The Molecular Machinery of Synaptic Plasticity and Its Potential Role in the Aetiology of SchizophreniaBRIAN J. MORRIS · 2026 · Molecular Neurobiology
- Transcranial direct current stimulation alleviates depression-like behaviors by activating the ACC-ZI neural circuitYue Wang, Kai Li, Tianzhi Yi, Bo Chen, Zibing Li, Haitong Chai, Huifei Hao, Hualin He, Xiaolang Du, S S Liu et al. · 2026 · Brain Research Bulletin
- Neural circuit dysfunction in major depressive disorder: a multiscale integrative perspectiveDhanveer Ahamed Bathurutheen, Thenmoly K Damodaran · 2026 · Current Opinion in Physiology
- Bidirectional control of vesicular GABA release, LTP, and amotivation by GluN2D-selective allosteric modulators and ketamineViktor Janos Oláh, Isabelle F. Witteveen, Tue G. Banke, Alexa M. Leahy, Ryan Keable, Riley E. Perszyk, Cara T. Khayat, TrangKimberly Thu Nguyen, Brianna J. Bixler, Frances Grace Ghinger et al. · 2026 · Cell Reports
- Subacute and long-term changes in cognitive functioning after administration of classic psychedelics, MDMA and ketamine: A systematic review of clinical and preclinical evidenceCatherine Kelly, Bart J. Cooley, Lilith Zeng, Tristan P. Hurzeler, Victoria Manning, Gavan P. McNally, Joshua Watt, Paul Haber, Kirsten C. Morley · 2026 · Neuroscience & Biobehavioral Reviews
- Advances in the Study of Mechanisms Underlying the Role of Gut Microbiota in Depressive Disorders慧 张 · 2026 · Advances in Clinical Medicine
- (Es‑)Ketamin: Praxis-UpdateStefan Vestring, Katharina Domschke, Claus Normann · 2026 · Der Nervenarzt
- Dysregulation of local inhibitory inputs onto laterodorsal tegmental nucleus cholinergic neurons drives depression-like behaviors in miceYaling Xu, Jun Du, Xia Li, Huapeng Diao, Lili Nie, Chao Yuan, Jiani Li, Yizheng Wang · 2026 · Molecular Psychiatry
- Ketamine enhances ketogenic diet-induced resilience to activity-based anorexia of adult mice through hippocampal synaptic plasticityJundi Wang, Olivia Ge, Yiru Dong, Emma J. Lee, Chiye J. Aoki · 2026 · Neuroscience
- The mPFC-reuniens-hippocampus pathway links brain circuitry and neural plasticity in antidepressant responseMaxime Veleanu, Louise E. Schuberth, Antje Kilias, Jakob Weber, Jan Warneke, Lovis M. Würz, Tim Schwär, Rebecca Heck, Joelle Müller, David H. Sarrazin et al. · 2026 · Nature Communications
- Cofilin 1 overexpression in the ventral hippocampus partially alleviates depressive-like behaviors in postmenopausal depression model mice through the dynamics of dendrites/dendritic spines in relevant brain regionsZong-Hao Yu, Geng Chen, Ming-Jun Ge, Zhenqiang Zhang, Jun-Xian Shen, Chuan Pan, Fei Han, Ya-Ping Lu, Hui Xu · 2026 · Pharmacology Biochemistry and Behavior
- Reframing stress adaptation as a dynamic system failure along a threat-response continuum: towards a phase-specific, mechanism-driven frameworkMunan Lin, Munan Lin, Junqing Dong · 2026 · Molecular Psychiatry
- Enzephalopathien bei psychiatrischen ErkrankungenJulia Reiff, Dieter F. Braus · 2026 · Springer eBooks
- Neuroplasticity-Based Treatment Prioritization in Major Depressive Disorder: A Two-Cohort StudyTalia Cohen Solal, Revital Amiaz, Moria Maman, Ziv Kassner, Guy Keller, Dror Ben Ami, Malgorzata Jaremko, Etay Aloni, Orit Goldman, Maurizio Fava M. D et al. · 2026 · medRxiv
- Ayahuasca Impairs Fear Memory Reconsolidation and Promotes Rapid Structural Plasticity in the Hippocampus and Prelimbic CortexDaiane Momo Daneluz, Alana Sueli dos Santos, Silvana Regina de Melo, Rúbia Maria Weffort de Oliveira, Cristina Aparecida Jark Stern · 2026 · Molecular Neurobiology
- Ketamine’s mechanisms of action in major depressive disorder and treatment-resistant depression: Is brain topological change a candidate convergent systems-level pathway?Gia Han Le, Sabrina Wong, Simryn Selby, Roger S. McIntyre · 2026 · Asian Journal of Psychiatry
- 5-HT2A receptors in layer 5 pyramidal neurons mediate the neuroplastic but not the hallucinogenic effects of psilocybinJacob Baker, Emily Kogan, Shaorong Ma, Ju Lu, Yi Zuo · 2026 · Nature Neuroscience
- Navigating the Complexities of Treatment-Resistant Depression in Late LifeCarolina B. Cross, Vasilis C. Hristidis, Eric J. Lenze · 2026 · FOCUS The Journal of Lifelong Learning in Psychiatry
- Psychoplastogens to Reduce Persistent Cognitive Symptoms for Traumatic Brain Injury as a Chronic ConditionHoda K AbouEich, Ali Izadi, Jonathan Lifshitz, David E. Olson, Gene G. Gurkoff · 2026 · Journal of Neurotrauma
- HINT1 in ventral hippocampal GABAergic neurons mediates depressive-like behaviorsShao-fu Li, Dian-ying Liu, Hui Zhang, Rui-chao Wen, Huiling Hu, Jing-miao Xv, Dan Cheng, Yonghui Dang · 2026 · Molecular Psychiatry