Deisseroth, Karl

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

Sohal, V. S., Zhang, F., Yizhar, O., & Deisseroth, K. (2009) · Nature

Neural dynamics and brain functionNeuroscience and Neuropharmacology Research

Cited by 2,606

Driving fast-spiking cells induces gamma rhythm and controls sensory responses

Cardin, J. A., Carlén, M., Meletis, K., Knoblich, U., Zhang, F., Deisseroth, K., Tsai, L.-H., & Moore, C. I. (2009) · Nature

Neural dynamics and brain functionNeuroscience and Neuropharmacology Research

Cited by 2,603

Neocortical excitation/inhibition balance in information processing and social dysfunction

Yizhar, O., Fenno, L. E., Prigge, M., Schneider, F., Davidson, T. J., O’Shea, D. J., Sohal, V. S., Goshen, I., Finkelstein, J., Paz, J. T., et al. (2011) · Nature

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 2,454

Structural and molecular interrogation of intact biological systems

Chung, K., Wallace, J., Kim, S.-Y., Kalyanasundaram, S., Andalman, A. S., Davidson, T. J., Mirzabekov, J. J., Zalocusky, K. A., Mattis, J., Denisin, A. K., et al. (2013) · Nature

Advanced Fluorescence Microscopy TechniquesCell Image Analysis Techniques

Cited by 2,008

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

Kravitz, A. V., Freeze, B. S., Parker, P. R. L., Kay, K., Thwin, M. T., Deisseroth, K., & Kreitzer, A. C. (2010) · Nature

Neurological disorders and treatmentsParkinson's Disease Mechanisms and Treatments

Cited by 1,885

Optogenetics in neural systems

Yizhar, O., Fenno, L. E., Davidson, T. J., Mogri, M., & Deisseroth, K. (2011) · Neuron

Photoreceptor and optogenetics researchNeuroscience and Neuropharmacology Research

Cited by 1,881

The development and application of optogenetics

Fenno, L., Yizhar, O., & Deisseroth, K. (2011) · Annual Review of Neuroscience

Photoreceptor and optogenetics researchAdvanced Fluorescence Microscopy Techniques

Cited by 1,822

Three-dimensional intact-tissue sequencing of single-cell transcriptional states

Wang, X., Allen, W. E., Wright, M. A., Sylwestrak, E. L., Samusik, N., Vesuna, S., Evans, K., Liu, C., Ramakrishnan, C., Liu, J., et al. (2018) · Science

Single-cell and spatial transcriptomicsMolecular Biology Techniques and Applications

Cited by 1,620

Natural neural projection dynamics underlying social behavior

Gunaydin, L. A., Grosenick, L., Finkelstein, J. C., Kauvar, I. V., Fenno, L. E., Adhikari, A., Lammel, S., Mirzabekov, J. J., Airan, R. D., Zalocusky, K. A., et al. (2014) · Cell

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 1,389

Neural substrates of awakening probed with optogenetic control of hypocretin neurons

Adamantidis, A. R., Zhang, F., Aravanis, A. M., Deisseroth, K., & de Lecea, L. (2007) · Nature

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 1,341

Input-specific control of reward and aversion in the ventral tegmental area

Lammel, S., Lim, B. K., Ran, C., Huang, K. W., Betley, M. J., Tye, K. M., Deisseroth, K., & Malenka, R. C. (2012) · Nature

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 1,300

Amygdala circuitry mediating reversible and bidirectional control of anxiety

Tye, K. M., Prakash, R., Kim, S.-Y., Fenno, L. E., Grosenick, L., Zarabi, H., Thompson, K. R., Gradinaru, V., Ramakrishnan, C., & Deisseroth, K. (2011) · Nature

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 1,289

Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

Tsai, H.-C., Zhang, F., Adamantidis, A., Stuber, G. D., Bonci, A., de Lecea, L., & Deisseroth, K. (2009) · Science

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 1,266

Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

Chaudhury, D., Walsh, J. J., Friedman, A. K., Juarez, B., Ku, S. M., Koo, J. W., Ferguson, D., Tsai, H.-C., Pomeranz, L., Christoffel, D. J., et al. (2013) · Nature

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 1,156

Dopamine neurons modulate neural encoding and expression of depression-related behaviour

Tye, K. M., Mirzabekov, J. J., Warden, M. R., Ferenczi, E. A., Tsai, H.-C., Finkelstein, J., Kim, S.-Y., Adhikari, A., Thompson, K. R., Andalman, A. S., et al. (2013) · Nature

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

Cited by 1,073

Tuning arousal with optogenetic modulation of locus coeruleus neurons

Carter, M. E., Yizhar, O., Chikahisa, S., Nguyen, H., Adamantidis, A., Nishino, S., Deisseroth, K., & de Lecea, L. (2010) · Nature Neuroscience

Sleep and Wakefulness ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 993

Encoding of conditioned fear in central amygdala inhibitory circuits

Ciocchi, S., Herry, C., Grenier, F., Wolff, S. B. E., Letzkus, J. J., Vlachos, I., Ehrlich, I., Sprengel, R., Deisseroth, K., Stadler, M. B., et al. (2010) · Nature

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 924

A skin-inspired organic digital mechanoreceptor

Tee, B. C.-K., Chortos, A., Berndt, A., Nguyen, A. K., Tom, A., McGuire, A., Lin, Z. C., Tien, K., Bae, W.-G., Wang, H., et al. (2015) · Science

Advanced Sensor and Energy Harvesting MaterialsTactile and Sensory Interactions

Cited by 882

Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward

Lobo, M. K., Covington, H. E., Chaudhury, D., Friedman, A. K., Sun, H., Damez-Werno, D., Dietz, D. M., Zaman, S., Koo, J. W., Kennedy, P. J., et al. (2010) · Science

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 880

Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking

Stuber, G. D., Sparta, D. R., Stamatakis, A. M., van Leeuwen, W. A., Hardjoprajitno, J. E., Cho, S., Tye, K. M., Kempadoo, K. A., Zhang, F., Deisseroth, K., et al. (2011) · Nature

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 878

Striatal Dopamine Release Is Triggered by Synchronized Activity in Cholinergic Interneurons

Threlfell, S., Lalic, T., Platt, N. J., Jennings, K. A., Deisseroth, K., & Cragg, S. J. (2012) · Neuron

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 845

Advanced CLARITY for rapid and high-resolution imaging of intact tissues

Tomer, R., Ye, L., Hsueh, B., & Deisseroth, K. (2014) · Nature Protocols

Advanced Fluorescence Microscopy TechniquesCell Image Analysis Techniques

Cited by 842

Genetic dissection of an amygdala microcircuit that gates conditioned fear

Haubensak, W., Kunwar, P. S., Cai, H., Ciocchi, S., Wall, N. R., Ponnusamy, R., Biag, J., Dong, H.-W., Deisseroth, K., Callaway, E. M., et al. (2010) · Nature

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 840

Locus coeruleus and dopaminergic consolidation of everyday memory

Takeuchi, T., Duszkiewicz, A. J., Sonneborn, A., Spooner, P. A., Yamasaki, M., Watanabe, M., Smith, C. C., Fernández, G., Deisseroth, K., Greene, R. W., et al. (2016) · Nature

Memory and Neural MechanismsNeurotransmitter Receptor Influence on Behavior

Cited by 827