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Cited by 5Ethics in Clinical ResearchEthics and bioethics in healthcareGenetic Associations and Epidemiology

The DOI matches its Crossref record; 9 of the 10 references it cites were found in a registry or an index.

Genome studies must account for history—Response

Open access
Ganna, Andrea, Verweij, Karin J.H., Nivard, Michel G., Maier, Robert, Wedow, Robbee, Busch, Alexander S., Abdellaoui, Abdel, Guo, Shengru, Sathirapongsasuti, J. Fah, 23andMe Research Team, Lichtenstein, Paul, Lundström, Sebastian, Långström, Niklas, Auton, Adam, Harris, Kathleen Mullan, Beecham, Gary W., Martin, Eden R., Sanders, Alan R., Perry, John R.B., Neale, Benjamin M., Zietsch, Brendan P.·2019·Science
DOI 10.1126/science.aaz8941
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Abstract

Our genome-wide association study (GWAS) on same-sex sexual behavior, which used data from the UK Biobank (1), was reviewed and approved by the UK Biobank Access Sub-Committee. We also sought stakeholder input from allies and advocates for the LGBTQIA+ community, as has been done in the past (2, 3). Despite these efforts, Holm and Ploug contend that broad biobank consent is insufficient. They argue that our study only tenuously qualifies as “health-related” and thus stretches the bounds of the participants' consent.

Overview

Integrity signals

Registry

Crossref · 10.1126/science.aaz8941

Cites

9 of 9 references verified0 citation errors · 0 not checkable

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Verification

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Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Recent research in other non-PD conditions has highlighted the potential transferability of targeted approaches like engineered symbiotic bacteria, CRISPR-Cas9 technologies, and bacteriophages for targeting specific bacterial populations.

    “Recent research in other non-PD conditions has highlighted the potential transferability of targeted approaches like engineered symbiotic bacteria, CRISPR-Cas9 technologies, and bacteriophages for targeting specific bacterial populations [171–173].”

    From The gut–brain axis in early Parkinson’s disease: from prodrome to prevention (2025) · cites this paper as [171]

Citations

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1 of the 10 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

  1. T. R. Thomas, D. Hofammann, B. G. McKenna, J. J. Michaelson, bioRxiv 10.1101/685982 (2019). · DOI
  2. L. Timmins, K. A. Rimes, Q. Rahman, Archiv. Sex. Behav. 10.1007/s10508-019-01502-2 (2019). · DOI

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Metadata

Authors
Ganna, A., Verweij, K. J. H., Nivard, M. G., Maier, R., Wedow, R., Busch, A. S., Abdellaoui, A., Guo, S., Sathirapongsasuti, J. F., 23andMe Research Team, Lichtenstein, P., Lundström, S., Långström, N., Auton, A., Harris, K. M., Beecham, G. W., Martin, E. R., Sanders, A. R., Perry, J. R. B., Neale, B. M., & Zietsch, B. P.
Affiliations
  • Broad Institute (US)
  • Amsterdam University Medical Centers (NL)
  • Vrije Universiteit Amsterdam (NL)
  • University of Copenhagen (DK)
  • University of Miami (US)
  • 23andMe (United States) (US)
  • Karolinska Institutet (SE)
  • University of Gothenburg (SE)
  • University of North Carolina at Chapel Hill (US)
  • Endeavor Health (US)
  • University of Cambridge (GB)
  • The University of Queensland (AU)
Corresponding author
  • Ganna, Andrea
  • Verweij, Karin J.H.
  • Perry, John R.B.
  • Neale, Benjamin M.
  • Zietsch, Brendan P.
ORCID
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
2019-12-20
Volume
366
Issue
6472
Pages
1461-1462
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
DOI
10.1126/science.aaz8941
OpenAlex
W2995765451
Cited by
5
References
10
Citations by year
2025: 1 · 2022: 1 · 2021: 2 · 2020: 1
Type
journal article
Language
en
Open access
Licence
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
  • Pure Amsterdam UMC (submittedVersion, other-oa)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
  • VU Research Portal (submittedVersion, other-oa)
Funders
  • Massachusetts General Hospital
  • Harvard University
  • Harvard T.H. Chan School of Public Health
  • Broad Institute
  • Amsterdam University Medical Centers
  • Universiteit van Amsterdam
  • Vrije Universiteit Amsterdam
  • Karolinska Institutet
  • Stanley Center for Psychiatric Research, Broad Institute
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics and bioethics in healthcare
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
Keywords
genome-wide association study, same-sex sexual behavior, UK Biobank, broad consent, research ethics
MeSH terms
Informed Consent, Genome, Sequence Analysis, DNA

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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