Targeting a neoantigen derived from a common TP53 mutation

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How good are my data and what is the resolution?

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Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma

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<i>TP53</i>Variations in Human Cancers: New Lessons from the IARC TP53 Database and Genomics Data: Human Mutation

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T cell-engaging therapies — BiTEs and beyond

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Extremely potent, rapid and costimulation‐independent cytotoxic T‐cell response against lymphoma cells catalyzed by a single‐chain bispecific antibody

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T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant

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Monoclonal TCR-redirected tumor cell killing

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Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers

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Crystal structure of the human T cell receptor CD3εγ heterodimer complexed to the therapeutic mAb OKT3

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Automated data collection for macromolecular crystallography

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TCR3d: The T cell receptor structural repertoire database

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Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy

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MHC‐Peptide Tetramers to Visualize Antigen‐Specific T Cells

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A flexible docking approach for prediction of T cell receptor–peptide–MHC complexes

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A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens

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A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell Engagers (BiTEs)

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Direct Detection and Quantification of Neoantigens

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Functional and Structural Characteristics of NY-ESO-1-related HLA A2-restricted Epitopes and the Design of a Novel Immunogenic Analogue

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MGD011, A CD19 x CD3 Dual-Affinity Retargeting Bi-specific Molecule Incorporating Extended Circulating Half-life for the Treatment of B-Cell Malignancies

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Structure of a TCR-Mimic Antibody with Target Predicts Pharmacogenetics

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Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes

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An in silico—in vitro Pipeline Identifying an HLA-A*02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients

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Targeting mutant p53-expressing tumours with a T cell receptor-like antibody specific for a wild-type antigen

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Successful engineering of a highly potent single-chain variable-fragment (scFv) bispecific antibody to target disialoganglioside (GD2) positive tumors

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Development of a T-cell Receptor Mimic Antibody against Wild-Type p53 for Cancer Immunotherapy

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Single MHC Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding

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