AI-based structure prediction empowers integrative structural analysis of human nuclear pores
Mosalaganti, Shyamal, Obarska-Kosinska, Agnieszka, Siggel, Marc, Taniguchi, Reiya, Turoňová, Beata, Zimmerli, Christian E., Buczak, Katarzyna, Schmidt, Florian H. +6 more·2022·Science
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- Limitations of Protein Structure Prediction Algorithms in Therapeutic Protein DevelopmentSarfaraz K. Niazi, Zamara Mariam, Rehan Zafar Paracha · 2024 · BioMedInformatics
- Structure and mechanics of the human nuclear pore complex basket using correlative AFM-fluorescence superresolution microscopyAnthony Vial, Luca Costa, Patrice Dosset, Pietro Rosso, Gaëlle Boutières, Orestis Faklaris, Heiko Haschke, Pierre‐Emmanuel Milhiet, Christine M. Doucet · 2023 · Nanoscale
- The Protein Structure Prediction Revolution and Its Implications for MedicineJohn Jumper, Demis Hassabis · 2023 · JAMA
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- A checkpoint function for Nup98 in nuclear pore formation suggested by novel inhibitory nanobodiesMireia Solà Colom, Zhenglin Fu, Philip Gunkel, Thomas Guettler, Sergei D. Trakhanov, Vasundara Srinivasan, Kathrin Gregor, Tino Pleiner, Dirk Görlich · 2024 · The EMBO Journal
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- Exploring the conformational diversity of proteinsAvner Schlessinger, Massimiliano Bonomi · 2022 · eLife
- Solving the nuclear pore puzzleThomas Schwartz · 2022 · Science
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- Distinct domains in Ndc1 mediate its interaction with the Nup84 complex and the nuclear membraneIngo Amm, Marion H Weberruss, Andrea Hellwig, Johannes Schwarz, Marianna Tatarek‐Nossol, Christian Lüchtenborg, Martina Kallas, Britta Brügger, Ed Hurt, Wolfram Antonin · 2023 · The Journal of Cell Biology
- All-Atom Biomolecular Simulation in the Exascale EraThomas L. Beck, Paolo Carloni, Dilip N. Asthagiri · 2024 · Journal of Chemical Theory and Computation
- Impact of distinct FG nucleoporin repeats on Nup98 self-associationAlain Ibáñez de Opakua, Christian F. Pantoja, Maria‐Sol Cima‐Omori, Christian Dienemann, Markus Zweckstetter · 2024 · Nature Communications
- Unraveling dynamic protein structures by two-dimensional infrared spectra with a pretrained machine learning modelFan Wu, Yan Hong Huang, Guokun Yang, Sheng Ye, Shaul Mukamel, Jun Jiang · 2024 · Proceedings of the National Academy of Sciences
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- Direct visualization of HIV-1 core nuclear import and its interplay with the nuclear poreZhen Hou, Stanley Fronik, Yao Shen, Long Chen, Christopher Thompson, Sarah Neumann, Peijun Zhang · 2025 · EMBO Reports
- CGBack: Diffusion Model for Backmapping Large-Scale and Complex Coarse-Grained Molecular SystemsDiego Ugarte La Torre, Yuji Sugita · 2025 · Journal of Chemical Information and Modeling
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- Structural anisotropy results in mechano-directional transport of proteins across nuclear poresFani Panagaki, Rafael Tapia‐Rojo, Tong Zhu, Natalie J. Milmoe, Patricia Paracuellos, Stephanie Board, Marc Mora, Jane Walker, Elena V. Rostkova, Andrew Stannard et al. · 2024 · Nature Physics
- The small GTPase Ran defines nuclear pore complex asymmetryJenny Sachweh, Mandy Börmel, Sven Klumpe, Anja Becker, Reiya Taniguchi, Marta Anna Kubańska, Verena Pintschovius, Eva Kaindl, Jürgen M. Plitzko, Florian Wilfling et al. · 2025 · Cell
- Nuclear mechanics as a determinant of nuclear pore complex plasticityC. Patrick Lusk, Kimberly J Morgan, Megan C. King · 2025 · Nature Cell Biology
- Particle fusion of super-resolution data reveals the unit structure of Nup96 in Nuclear Pore ComplexWenxiu Wang, Arjen J. Jakobi, Yule Wu, Jonas Ries, Sjoerd Stallinga, Bernd Rieger · 2023 · Scientific Reports
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- Mechanisms of Messenger RNA Packaging and ExportRupert Faraway, Daniel Zenklusen, Clemens Plaschka · 2025 · Annual Review of Cell and Developmental Biology
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- Plant pathogens and symbionts target the plant nucleusNeda Tehrani, Raka M. Mitra · 2023 · Current Opinion in Microbiology
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- Scaling of the GROMACS Molecular Dynamics Code to 65k CPU Cores on an HPC ClusterCarsten Kutzner, Vedran Miletić, Karen Palacio‐Rodríguez, Markus Rampp, Gerhard Hummer, Bert L. de Groot, Helmut Grubmüller · 2025 · Journal of Computational Chemistry
- AI protocol for retrieving protein dynamic structures from two-dimensional infrared spectraSheng Ye, Lvshuai Zhu, Zhicheng Zhao, Fan Wu, Жипенг Ли, Binbin Wang, Kai Zhong, Changyin Sun, Shaul Mukamel, Jun Jiang · 2025 · Proceedings of the National Academy of Sciences
- IgStrand: A universal residue numbering scheme for the immunoglobulin-fold (Ig-fold) to study Ig-proteomes and Ig-interactomesCaesar Tawfeeq, Jiyao Wang, Umesh Khaniya, Thomas Madej, James Song, Ravinder Abrol, Philippe Youkharibache · 2025 · PLoS Computational Biology
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- SARS-CoV-2 Orf6 is positioned in the nuclear pore complex by Rae1 to inhibit nucleocytoplasmic transportTadashi Makio, Ke Zhang, Nicole Love, Fred David Mast, Xue Liu, Mohamed Elaish, Tom C. Hobman, John D. Aitchison, Beatriz M. A. Fontoura, Richard W. Wozniak · 2024 · Molecular Biology of the Cell
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- In situ architecture of the nuclear pore complex of the higher plant Arabidopsis thalianaSanchez Carrillo, Ingrid Berenice, Hoffmann, Patrick C., Obarska-Kosinska, Agnieszka, Fourcassié, Victor, Beck, Martin, Germain, Hugo · 2025 · Nature Plants
- The transformative impact of AI-enabled AlphaFold 3: evolution, current status, and future prospects in structural biologyChiranjib Chakraborty, Manojit Bhattacharya, Sang-Soo Lee · 2026 · Frontiers in Artificial Intelligence
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- Case report: Compound heterozygous NUP85 variants cause autosomal recessive primary microcephalyEthiraj Ravindran, Gaëtan Lesca, Louis Januel, Linus Goldgruber, Achim Dickmanns, Henri Margot, Angela Maria Kaindl · 2023 · Frontiers in Neurology
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- Human spermatogenesis leads to a reduced nuclear pore structure and functionÁlia dos Santos, Oliver Knowles, Tom Dendooven, Thomas Hale, Victoria L. Hale, Alister Burt, Piotr Kolata, Giuseppe Cannone, Dom Bellini, David Barford et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
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