The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Microbiota and maintenance of skin barrier function
Abstract
Human skin forms a protective barrier against the external environment and is our first line of defense against toxic, solar, and pathogenic insults. Our skin also defines our outward appearance, protects our internal tissues and organs, acts as a sensory interface, and prevents dehydration. Crucial to the skin’s barrier function is the colonizing microbiota, which provides protection against pathogens, tunes immune responses, and fortifies the epithelium. Here we highlight recent advances in our understanding of how the microbiota mediates multiple facets of skin barrier function. We discuss recent insights into pathological host–microbiota interactions and implications for disorders of the skin and distant organs. Finally, we examine how microbiota-based mechanisms can be targeted to prevent or manage skin disorders and impaired wound healing.
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Cites
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MAIT cells are imprinted by the microbiota in early life and promote tissue repair
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Cited by
Ma, Z., Zuo, T., Frey, N., & Rangrez, A. Y. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01946-6 · Cited by 259
Skin Microbiome, Metabolome and Skin Phenome, from the Perspectives of Skin as an Ecosystem
Chen, H., Zhao, Q., Zhong, Q., Duan, C., Krutmann, J., Wang, J., & Xia, J. (2022) · Phenomics · doi:10.1007/s43657-022-00073-y · Cited by 79
Update on the pathogenesis of atopic dermatitis.
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Native human and mouse skin infection models to study Candida auris-host interactions
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Metadata
- Authors
- Harris-Tryon, T. A., & Grice, E. A.
- Venue
- Science
- Published
- 2022-05-27
- Volume
- 376
- Issue
- 6596
- Pages
- 940-945
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W4281557603
- Cited by
- 651
- References
- 15
- FWCI
- 103.38
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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