Cell surface polysaccharides of Bifidobacterium bifidum induce the generation of Foxp3 + regulatory T cells

Colorimetric Method for Determination of Sugars and Related Substances

DuBois, M., Gilles, K. A., Hamilton, J. K., Rebers, P. A., & Smith, F. (1956) · Analytical Chemistry · doi:10.1021/ac60111a017 · Cited by 52,269

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

Hori, S., Nomura, T., & Sakaguchi, S. (2003) · Science · doi:10.1126/science.1079490 · Cited by 8,187

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

Furusawa, Y., Obata, Y., Fukuda, S., Endo, T. A., Nakato, G., Takahashi, D., Nakanishi, Y., Uetake, C., Kato, K., Kato, T., et al. (2013) · Nature · doi:10.1038/nature12721 · Cited by 5,549

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

Arpaia, N., Campbell, C., Fan, X., Dikiy, S., van der Veeken, J., deRoos, P., Liu, H., Cross, J. R., Pfeffer, K., Coffer, P. J., et al. (2013) · Nature · doi:10.1038/nature12726 · Cited by 4,838

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivanov, I. I., Atarashi, K., Manel, N., Brodie, E. L., Shima, T., Karaoz, U., Wei, D., Goldfarb, K. C., Santee, C. A., Lynch, S. V., et al. (2009) · Cell · doi:10.1016/j.cell.2009.09.033 · Cited by 4,554

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

Atarashi, K., Tanoue, T., Shima, T., Imaoka, A., Kuwahara, T., Momose, Y., Cheng, G., Yamasaki, S., Saito, T., Ohba, Y., et al. (2011) · Science · doi:10.1126/science.1198469 · Cited by 3,752

An Immunomodulatory Molecule of Symbiotic Bacteria Directs Maturation of the Host Immune System

Mazmanian, S. K., Liu, C. H., Tzianabos, A. O., & Kasper, D. L. (2005) · Cell · doi:10.1016/j.cell.2005.05.007 · Cited by 2,910

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

Atarashi, K., Tanoue, T., Oshima, K., Suda, W., Nagano, Y., Nishikawa, H., Fukuda, S., Saito, T., Narushima, S., Hase, K., et al. (2013) · Nature · doi:10.1038/nature12331 · Cited by 2,872

Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

Fontenot, J. D., Rasmussen, J. P., Williams, L. M., Dooley, J., Farr, A. G., & Rudensky, A. Y. (2005) · Immunity · doi:10.1016/j.immuni.2005.01.016 · Cited by 2,302

Inducible Foxp3 + regulatory T-cell development by a commensal bacterium of the intestinal microbiota

Round, J. L., & Mazmanian, S. K. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909122107 · Cited by 2,233

Modulation of T Regulatory and Dendritic Cell Phenotypes Following Ingestion of Bifidobacterium longum, AHCC® and Azithromycin in Healthy Individuals

Chowdhury, A. H., Cámara, M., Verma, C., Eremin, O., Kulkarni, A. D., & Lobo, D. N. (2019) · Nutrients · doi:10.3390/nu11102470 · Cited by 22

Host–microbiome intestinal interactions during early life: considerations for atopy and asthma development

Pettersen, V. K., & Arrieta, M. (2020) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0000000000000629 · Cited by 22

Regulating colonic dendritic cells by commensal glycosylated large surface layer protein A to sustain gut homeostasis against pathogenic inflammation

Ge, Y., Gong, M., Zadeh, M., Li, J., Abbott, J. R., Li, W., Morel, L. M., Sonon, R. N., Supekar, N. T., Azadi, P., et al. (2019) · Mucosal Immunology · doi:10.1038/s41385-019-0210-0 · Cited by 24

LsrR-like protein responds to stress tolerance by regulating polysaccharide biosynthesis in Lactiplantibacillus plantarum

Meng, F., Lyu, Y., Zhao, H., Lyu, F., Bie, X., Lu, Y., Zhao, M., Chen, Y., & Lu, Z. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.11.180 · Cited by 20

Advancements in rheumatoid arthritis therapy: a journey from conventional therapy to precision medicine via nanoparticles targeting immune cells

Laha, A., Nasra, S., Bhatia, D. D., & Kumar, A. (2024) · Nanoscale · doi:10.1039/d4nr02182g · Cited by 25

Metagenomics and Untargeted Metabolomics Analysis Revealed the Probiotic and Postbiotic Derived from Lactiplantibacillus plantarum DPUL F232 Alleviate Whey Protein-Induced Food Allergy by Reshaping Gut Microbiota and Regulating Key Metabolites

Feng, L., Guo, Z., Yao, W., Mu, G., & Zhu, X. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c08203 · Cited by 21

Lactobacillus reuteri CCFM1072 and CCFM1040 with the role of Treg cells regulation alleviate airway inflammation through modulating gut microbiota in allergic asthma mice

Li, L., Fang, Z., Liu, Z., Zhao, J., Zhang, H., Wang, S., He, J., Lu, W., & Chen, W. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104286 · Cited by 21

Bacteria-immune cells dialog and the homeostasis of the systems

Guzman-Bautista, E. R., Suzuki, K., Asami, S., & Fagarasan, S. (2020) · Current Opinion in Immunology · doi:10.1016/j.coi.2020.05.010 · Cited by 21

Supplementation with postbiotic from Bifidobacterium Breve BB091109 improves inflammatory status and endocrine function in healthy females: a randomized, double-blind, placebo-controlled, parallel-groups study

Motei, D. E., Beteri, B., Hepsomali, P., Tzortzis, G., Vulevic, J., & Costabile, A. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1273861 · Cited by 19

Phylogenetic and Comparative Genomic Analysis of Lactobacillus fermentum Strains and the Key Genes Related to their Intestinal Anti-Inflammatory Effects

Zhao, Y., Zhang, C., Yu, L., Tian, F., Zhao, J., Zhang, H., Chen, W., & Zhai, Q. (2021) · Engineering · doi:10.1016/j.eng.2020.09.016 · Cited by 18

Resolving the Mutually Exclusive Immune Responses of Chitosan with Nanomechanics and Immunological Assays

Lee, S., Byun, S., Lee, C., Park, S. H., Rudra, D., Iwakura, Y., Lee, Y. J., Im, S., & Hwang, D. S. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202102667 · Cited by 19

Polysaccharide BAP1 of Bifidobacterium adolescentis CCDM 368 is a biologically active molecule with immunomodulatory properties

Pacyga-Prus, K., Jakubczyk, D., Sandström, C., Šrůtková, D., Pyclik, M. J., Leszczyńska, K., Ciekot, J., Razim, A., Schwarzer, M., & Górska, S. (2023) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2023.120980 · Cited by 19

The role of gut microbiota in infectious diseases

Cai, Y., Chen, L., Zhang, S., Zeng, L., & Zeng, G. (2022) · WIREs Mechanisms of Disease · doi:10.1002/wsbm.1551 · Cited by 18

Bifidobacterium bifidum FJSWX19M5 alleviated 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced chronic colitis by mitigating gut barrier injury and increasing regulatory T cells

Qu, D., Yu, L., Tian, F., Zhang, H., Chen, W., Gu, Z., & Zhai, Q. (2022) · Food & Function · doi:10.1039/d2fo02659g · Cited by 19

Microbial Components and Effector Molecules in T Helper Cell Differentiation and Function

Lee, C., Lee, H., Park, J. C., & Im, S. (2023) · Immune Network · doi:10.4110/in.2023.23.e7 · Cited by 19

Both live and heat killed Lactiplantibacillus plantarum DPUL-F232 alleviate whey protein-induced food allergy by regulating cellular immunity and repairing the intestinal barrier

Feng, L., Chen, G., Guo, Z., Yao, W., Li, X., Mu, G., & Zhu, X. (2024) · Food & Function · doi:10.1039/d4fo00105b · Cited by 18

Comparative Genomic Analysis of Bifidobacterium bifidum Strains Isolated from Different Niches

Lu, W., Pei, Z., Zang, M., Lee, Y.-K., Zhao, J., Chen, W., Wang, H., & Zhang, H. (2021) · Genes · doi:10.3390/genes12101504 · Cited by 17

Crosstalk Among Gut Microbiota, Microbial Metabolites, and Inflammatory Cytokines: Current Understanding and Future Directions

Wu, G., Wang, R., Wang, Y., Sun, S., Chen, J., & Zhang, Q. (2025) · Foods · doi:10.3390/foods14223836 · Cited by 17

Engineering bacteria for enhanced tumor therapy: from surface modification to synthetic genetic circuits

Wang, Y., Xiao, S., Yu, W., Han, B. R., & Guo, G. F. (2025) · Journal of Hematology & Oncology · doi:10.1186/s13045-025-01766-3 · Cited by 20

Epithelial-microbial diplomacy: escalating border tensions drive inflammation in inflammatory bowel disease

King, S. J., & McCole, D. F. (2019) · Intestinal Research · doi:10.5217/ir.2018.00170 · Cited by 18

Staphylococcus succinus 14BME20 Prevents Allergic Airway Inflammation by Induction of Regulatory T Cells via Interleukin-10

Song, J., Lim, H. X., Lee, A., Kim, S., Lee, J., & Kim, T. S. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01269 · Cited by 17

Interaction between tissue-dwelling helminth and the gut microbiota drives mucosal immunoregulation

Wang, Y., Guo, A., Zou, Y., Mu, W., Zhang, S., Shi, Z., Liu, Z., Cai, X., Zhu, X., & Wang, S. (2023) · npj Biofilms and Microbiomes · doi:10.1038/s41522-023-00410-7 · Cited by 16

The human microbiome: redefining cancer pathogenesis and therapy

Adlakha, Y. K., & Chhabra, R. (2025) · Cancer Cell International · doi:10.1186/s12935-025-03787-x · Cited by 20

Research progress on the regulation mechanism of probiotics on the microecological flora of infected intestines in livestock and poultry

Shi, S., Liu, J., Dong, J., Hu, J., Yu- cui, L. I. U., Feng, J., & Zhou, D. (2021) · Letters in Applied Microbiology · doi:10.1111/lam.13629 · Cited by 16

Regulatory T cells as therapeutic targets and mediators

Sharma, A., & Rudra, D. (2019) · International Reviews of Immunology · doi:10.1080/08830185.2019.1621310 · Cited by 17

Commensal microbe-derived butyrate enhances T follicular helper cell function to boost mucosal vaccine efficacy

Ko, H., Kim, C. J., Choi, S., Noh, J., Kim, S. W., Lee, J., Byun, S., Lee, H., Park, J. C., Park, H. E., et al. (2026) · Microbiome · doi:10.1186/s40168-025-02284-7 · Cited by 17

Astragalus Polysaccharide Enhances Voriconazole Metabolism under Inflammatory Conditions through the Gut Microbiota

Wang, X., Hu, X., Ye, C., Zhao, J., Tan, S. C., Zhou, L., Zhao, C., Wu, K. H., Yang, X., Wei, J., et al. (2024) · Journal of Clinical and Translational Hepatology · doi:10.14218/jcth.2024.00024 · Cited by 15

Emodin modulates gut microbial community and triggers intestinal immunity

Mabwi, H. A., Lee, H. J., Hitayezu, E., Mauliasari, I. R., Pan, C., Mwaikono, K. S., Komba, E. V. G., Lee, C., & Hyun, K. (2022) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.12221 · Cited by 15

Can fecal microbiota transplantations modulate autoimmune responses in type 1 diabetes?

Snethlage, C. M. F., de Wit, D. F., Wortelboer, K., Rampanelli, E., Hanssen, N. M. J., & Nieuwdorp, M. (2024) · Immunological Reviews · doi:10.1111/imr.13345 · Cited by 13

Comparative Effects of Probiotics and Paraprobiotics Derived from Lactiplantibacillus plantarum, Latilactobacillus sakei, and Limosilactobacillus reuteri in a DSS-Induced Ulcerative Colitis Mouse Model

Kang, Y. Y., Song, H. J., Park, S. Y., Oh, D. N., Kim, G. Y., Been, N. Y., Kim, D. Y., Lee, E. J., Nam, B., & Lee, J. M. (2025) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2411.11045 · Cited by 13

Dietary intervention with functional foods modulating gut microbiota for improving the efficacy of COVID-19 vaccines

Oh, S.-Y., & Seo, H. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e15668 · Cited by 13

Immunomodulatory mechanisms of the gut microbiota and metabolites on regulatory T cells in rheumatoid arthritis

Xu, X., Zhou, J., Xie, H., Zhang, R., Gu, B., Liu, L., Liu, M., & Chang, X.-R. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1610254 · Cited by 14

Cell surface polysaccharides in the gut microbiota: occurrence, structure and role

Laplanche, V., Speciale, I., Castro, C. D., & Juge, N. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2536082 · Cited by 12

Host–gut microbiota interactions in health and disease: mechanisms and intervention strategies

Han, Y., Wang, Z., Xie, J., Yang, G., Su, M., Wang, S., Yang, M., Yu, H., Li, M., Wang, L., et al. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1785607 · Cited by 13

The NQR Complex Regulates the Immunomodulatory Function of Bacteroides thetaiotaomicron

Engelhart, M. J., Glowacki, R. W. P., Till, J. M., Harding, C. V., Martens, E. C., & Ahern, P. P. (2023) · The Journal of Immunology · doi:10.4049/jimmunol.2200892 · Cited by 13

The Critical Role of Regulatory T Cells in Immune Tolerance and Rejection Following Liver Transplantation: Interactions With the Gut Microbiome

Lee, S. K., Kwon, J. H., Jang, J. W., Bae, S. H., Yoon, S. K., Jung, E. S., & Choi, J. Y. (2024) · Transplantation · doi:10.1097/tp.0000000000005220 · Cited by 13

Advances in research on gut microbiota and allergic diseases in children

Ke, H., Yao, H., & Wei, P. (2025) · Current Research in Microbial Sciences · doi:10.1016/j.crmicr.2025.100362 · Cited by 16

Postbiotics ameliorate DSS-induced colitis in mice by regulating gut microbiota, promoting tryptophan metabolism, and activating AhR/ IL-22 signaling pathway

Han, M., Hou, M., Liu, Y., Li, H., & Gao, Z. (2025) · Food Bioscience · doi:10.1016/j.fbio.2025.106828 · Cited by 11

Anti-Obesity Potential through Regulation of Carbohydrate Uptake and Gene Expression in Intestinal Epithelial Cells by the Probiotic Lactiplantibacillus plantarum MGEL20154 from Fermented Food

Park, S. Y., Choi, J. W., Oh, D. N., Lee, E. J., Kim, D. P., Yoon, S. J., Jang, W. J., Han, S. J., Lee, S., & Lee, J. M. (2023) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2212.12005 · Cited by 11

Gut Microbiota Defines Functional Direction of Colonic Regulatory T Cells with Unique TCR Repertoires

Byun, S., Lee, J., Choi, Y. H., Ko, H., Lee, C., Park, J. C., Kim, S. W., Lee, H., Sharma, A., Kim, K. S., et al. (2024) · The Journal of Immunology · doi:10.4049/jimmunol.2300395 · Cited by 11

Synergistic effect of 2′-Fucosyllactose or galactooligosaccharide with Bifidobacterium bifidum DNG6 improves the intestinal barrier by modulating the SCFAs-TLR4/NF-κB cascade response in DSS-induced colitis in mice

Sun, C., Wang, Y.-Q., Wang, X., Zhang, G., Cao, H.-F., Song, G., Liu, L., Li, C., Boyarineva, I. V., & Du, P. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105814 · Cited by 11

Polysaccharide-functionalized drug delivery system for metastatic cancer therapy

Chen, S., Ye, Y., Pang, S., Li, S., Li, M., Guo, R., & He, Q. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.114070 · Cited by 12

Metabolic hallmarks of type 2 diabetes compromise T cell function

Liang, Y., Chen, W., Gao, Q., Tan, K. C. B., Lee, C., & Ling, G. S. (2025) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2025.08.005 · Cited by 11

Intestinal factors promoting the development of RORγt+ cells and oral tolerance

López‐Fandiño, R., Molina, E., & Lozano‐Ojalvo, D. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1294292 · Cited by 11

Microbiota from human infants consuming secretors or non-secretors mothers’ milk impacts the gut and immune system in mice

Gurung, M., Schlegel, B. T., Rajasundaram, D., Fox, R., Bode, L., Yao, T., Lindemann, S. R., LeRoith, T., Read, Q. D., Simecka, C. M., et al. (2024) · mSystems · doi:10.1128/msystems.00294-24 · Cited by 11

Effects of health-related claims on millennials’ willingness to pay for probiotics in the U.S.: Implications for regulation

Kolady, D., Kattelmann, K. K., & Scaria, J. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.103434 · Cited by 11

Sequestration of gut pathobionts in intraluminal casts, a mechanism to avoid dysregulated T cell activation by pathobionts

Sassone‐Corsi, M., Azriel, S., Simon, A., Ramanan, D., Ortiz-Lopez, A., Chen, F., Yissachar, N., Mathis, D. J., & Benoist, C. O. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2209624119 · Cited by 11

Core fucosylation of maternal milk N -glycans imparts early-life immune tolerance through gut microbiota-dependent regulation in RORγt + Treg cells

Li, Y., Ning, X., Zhao, Z., He, X., Xue, Q., Zhou, M., Li, W., & Li, M. (2024) · Food & Function · doi:10.1039/d4fo00230j · Cited by 9

Immunosuppressant imprecision: multidirectional effects on metabolism and microbiome

Kensiski, A., Gavzy, S. J., Wu, L., Mas, V. R., Ma, B., & Bromberg, J. S. (2025) · Clinical Microbiology Reviews · doi:10.1128/cmr.00178-24 · Cited by 11

Exopolysaccharide from Lacticaseibacillus rhamnosus induces IgA production in airways and alleviates allergic airway inflammation in mouse model

Šrůtková, D., Kozáková, H., Novotna, T., Górska, S., Hermanová, P. P., Hudcovic, T., Svabova, T., Šinkora, M., & Schwarzer, M. (2023) · European Journal of Immunology · doi:10.1002/eji.202250135 · Cited by 10

Bifidobacteria: A probable missing puzzle piece in the pathogenesis of multiple sclerosis

Toghi, M., Bitarafan, S., Kasmaei, H. D., & Ghafouri‐Fard, S. (2019) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2019.101378 · Cited by 11

2’-Fucosyllactose alleviate immune checkpoint blockade-associated colitis by reshaping gut microbiota and activating AHR pathway

Yan, S., Yu, L., Tian, F., Zhao, J., Chen, W., & Zhai, Q. (2023) · Food Science and Human Wellness · doi:10.26599/fshw.2022.9250205 · Cited by 12

Bifidogenic Effect of Human Milk Oligosaccharides on Pediatric IBD Fecal Microbiota

Otaru, N., Bajic, D., den Abbeele, P. V., Velde, S. V., Biervliet, S. V., Steinert, R. E., & Rehman, A. (2024) · Microorganisms · doi:10.3390/microorganisms12101977 · Cited by 9

Targeting CD4+ T cells through gut microbiota: therapeutic potential of traditional Chinese medicine in inflammatory bowel disease

Lu, X., Xv, Y., Hu, W., Sun, B., & Hu, H. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1557331 · Cited by 9

The gut microbiota in high-altitude medicine: intersection of hypoxic adaptation and disease management

Chen, Q., Huang, D., Liu, J., Jia, N., Shen, Z., Pei, C., Chen, C., Liu, Y., Wang, Y., Shi, S., et al. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1705487 · Cited by 11

The immunobiology and therapeutic potential of regulatory T cells in autoimmune diseases and allergic diseases

Xie, W.-W., Huang, J.-B., Zhou, Y.-C., Yuan, J.-Y., Feng, J.-X., Shi, X.-H., Tian, L., Zeng, X.-H., Qiu, S.-Q., Zhao, M.-Z., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1709915 · Cited by 10

Controlled Complexity: Optimized Systems to Study the Role of the Gut Microbiome in Host Physiology

Glowacki, R. W. P., Engelhart, M. J., & Ahern, P. P. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.735562 · Cited by 10

Species- or genus-dependent immunostimulatory effects of gut-derived potential probiotics

Feng, S., Wang, S., Qu, D., Li, J., Tian, F., Yu, L., Zhang, H., Zhao, J., Chen, W., & Zhai, Q. (2022) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2022.11.001 · Cited by 10

The glycocalyx of Lacticaseibacillus paracasei NPB01 presents two different rhamnose-rich polysaccharides with non-equivalent immunomodulating activities

Armiento, S., Oglio, F., Masino, A., Iovine, A., Trivelli, X., Molinaro, A., Guérardel, Y., Canani, R. B., & Castro, C. D. (2025) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2025.123742 · Cited by 8

Competitive Inhibition of LPS Binding to CD14 by Bifidobacterium adolescentis FXJWS49M31 Polysaccharide Alleviates TNF-α Secretion and Inflammatory Responses

Yan, S., Yu, L., Tian, F., Zhao, J., Chen, W., & Zhai, Q. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c05590 · Cited by 8

Exploring the Fecal Metabolome in Infants With Cow's Milk Allergy: The Distinct Impacts of Cow's Milk Protein Tolerance Acquisition and of Synbiotic Supplementation

Zhu, P., Savova, M. V., Kindt, A. S. D., the PRESTO study team, Wopereis, H., Belzer, C., Harms, A. C., & Hankemeier, T. (2024) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202400583 · Cited by 10

Bioderived materials that disarm the gut mucosal immune system: Potential lessons from commensal microbiota

Harriman, R., & Lewis, J. S. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.05.045 · Cited by 9

A New Formulation of Probiotics Attenuates Calcipotriol-Induced Dermatitis by Inducing Regulatory Dendritic Cells

Xu, B., Ling, S., Xu, X., Liu, X., Wang, A., Zhou, Y., Luo, Y., Li, W., & Yao, X. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.775018 · Cited by 8

Colonic goblet cell-associated antigen passages mediate physiologic and beneficial translocation of live gut bacteria in preweaning mice

Udayan, S., Floyd, A. N., John, V., Barrios, B. E., Rusconi, B. A., McDonald, K. G., Schill, E. M., Kulkarni, D. H., Martin, A. L., Gutierrez, R., et al. (2025) · Nature Microbiology · doi:10.1038/s41564-025-01965-1 · Cited by 7

Beneficial Bacteria in the Gut Microbiota May Lead to Improved Metabolic and Immunological Status in Chronic Obstructive Pulmonary Disease

Passos, F. C., de Oliveira, L. M. G., Jesus, F. R., Zanette, D. L., Neto, O. L. L., Neves, M. C. L. C., Lemos, A. C. M., & Baccan, G. C. (2024) · Medical Sciences · doi:10.3390/medsci12030041 · Cited by 9

Critical roles of a housekeeping sortase of probiotic Bifidobacterium bifidum in bacterium–host cell crosstalk

Ishikawa, E., Yamada, T., Yamaji, K., Serata, M., Fujii, D., Umesaki, Y., Tsuji, H., Nomoto, K., Ito, M., Okada, N., et al. (2021) · iScience · doi:10.1016/j.isci.2021.103363 · Cited by 7

Alfalfa intervention alters the colonization of rumen epithelial bacteria to promote rumen development and lamb health during early life

Yang, B., Chen, H., Liu, Y., Luo, Y., He, B., Wang, S., & Wang, J. (2023) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2023.115797 · Cited by 7

Microbiome-immune crosstalk in allergic rhinitis: lung and intestinal microbiota mechanisms

Wang, C., Zhai, C., Hu, S., & Lu, Y. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1697226 · Cited by 6

Metabolic crosstalk between intestinal microbiota and dendritic cells: from homeostasis to inflammation

Wang, M., Su, H., & Liu, J. (2025) · Acta Biochimica et Biophysica Sinica · doi:10.3724/abbs.2025231 · Cited by 7

Peptidoglycan from Bifidobacterium adolescentis enhances IL-10 production in regulatory B cells to alleviate gut inflammation

Lee, S., Lee, Y. S., Lee, H., Yu, J., Kim, K. O., Kim, T.-Y., Lee, S.-H., Qiao, Y., KIM, S., & Kweon, M. (2026) · Gut Microbes · doi:10.1080/19490976.2025.2611603 · Cited by 8

Role of intestinal microbiota in regulation of immune reactions of gut-associated lymphoid tissue under stress and following the modulation of its composition by antibiotics and probiotics administration

Topol, I. A., Polyakova, I. S., & Elykova, A. V. (2023) · Journal of microbiology epidemiology immunobiology · doi:10.36233/0372-9311-270 · Cited by 7

BT1549 coordinates the in vitro IL-10 inducing activity of Bacteroides thetaiotaomicron

Engelhart, M. J., Brock, O. D., Till, J. M., Glowacki, R. W. P., Cantwell, J. W., Clarke, D. J., Wesener, D. A., & Ahern, P. P. (2025) · Microbiology Spectrum · doi:10.1128/spectrum.01669-24 · Cited by 7

Can Microbes Boost Tregs to Suppress Food Sensitivities?

Siller, M., Zeng, Y., & Hinterleitner, R. (2020) · Trends in Immunology · doi:10.1016/j.it.2020.09.005 · Cited by 7

Chronic rejection as a persisting phantom menace in organ transplantation: a new hope in the microbiota?

Mongodin, E. F., Saxena, V., Iyyathurai, J., Lakhan, R., Ma, B., Silverman, E., Lee, Z. L., & Bromberg, J. S. (2021) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0000000000000929 · Cited by 6

Comparison of gut microbiota compositions and corresponding genetic and metabolic features between guttate and plaque psoriasis by metagenomic sequencing

Wang, X., Liu, X., Xiao, S., Zhang, Z., Wu, L., Cheng, Y., Tan, Y., Zhang, G., & Jiang, C. (2022) · Microbial Pathogenesis · doi:10.1016/j.micpath.2022.105560 · Cited by 6

Bile resistance mechanisms in probiotics: From structural adaptation to metabolic regulation

Hu, J.-W., Guo, S.-J., Zhang, L.-W., & Guo, C.-F. (2026) · Food Bioscience · doi:10.1016/j.fbio.2026.108282 · Cited by 5

Lactiplantibacillus plantarum CCFM8610 mitigates oxidative stress-related intestinal aging through its metabolite indole-3-lactic acid

Fang, J., Dai, Y., Chen, J., Zhang, H., Li, H., & Chen, W. (2025) · Food Bioscience · doi:10.1016/j.fbio.2024.105822 · Cited by 6

Mechanisms and therapeutic advances of gut metabolites in the regulation of neuroimmune inflammatory diseases

Shen, X., Zheng, C., Lin, R., Wang, J., & Chen, Z. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1795042 · Cited by 5

Investigation into IgG/IgE binding capacity and gut microbiota of digestion products derived from glycated ovalbumin

Mao, J., Shao, Y., Wang, H., Liu, J., & Tu, Z. (2024) · Food Science and Human Wellness · doi:10.26599/fshw.2023.9250045 · Cited by 5

Immunobiotic Bacteria Attenuate Hepatic Fibrosis through the Modulation of Gut Microbiota and the Activation of Aryl‐Hydrocarbon Receptors Pathway in Non‐Alcoholic Steatohepatitis Mice

Kanmani, P., Villena, J., Lim, S.-K., Song, E., Nam, Y., & Kim, H. (2024) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202400227 · Cited by 5

Gene prediction of immune cells association between gut microbiota and colorectal cancer: a Mendelian randomization study

Zhong, Y., Chen, G., Chen, M., Cui, J., Tan, Q., & Xiao, Z. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1460936 · Cited by 7

Gut microbiota and immunology of the gastrointestinal tract

Manley, G. C. A., Lee, Y. K., & Zhang, Y. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813037-7.00004-2 · Cited by 5

Bifidobacterial Postbiotics as Health-promoting Agents in Dairy Products

Rad, A. H., Moghadam, S. K., Mortazavian, A. M., Abachi, S., & Allahmadadi, S. (2023) · Current Functional Foods · doi:10.2174/2666862901666230818093034 · Cited by 4

Control of Asthma and Allergy by Regulatory T Cells

Jheng, M.-J., & Kita, H. (2024) · International Archives of Allergy and Immunology · doi:10.1159/000540407 · Cited by 5

Postbiotic effects elicited by heat-inactivated Lacticaseibacillus rhamnosus GG against cow’s milk allergy in human cells

Oglio, F., Paparo, L., Carucci, L. R., Gaeta, A., Armiento, S., Coppola, S., Molinaro, A., Castro, C. D., Masino, A., Mauriello, V., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1671729 · Cited by 4

Arabinogalactan from Cynanchum atratum induces tolerogenic dendritic cells in gut to restrain autoimmune response and alleviate collagen-induced arthritis in mice

Li, N., Xu, T., Wu, Z., Zhao, Y., Ruan, M., Xu, H., Chen, W., Wang, H., Wang, S., Wang, Y., et al. (2024) · Phytomedicine · doi:10.1016/j.phymed.2024.156269 · Cited by 4

Differences in the effects and action modes of gut commensals against dextran sulfate sodium-induced intestinal inflammation

Qu, D., Gu, Z., Feng, S., Yu, L., Tian, F., Zhang, H., Chen, W., & Zhai, Q. (2023) · Food Science and Human Wellness · doi:10.26599/fshw.2022.9250100 · Cited by 5

Phosphorylation-dependent immunomodulatory properties of B.PAT polysaccharide isolated from Bifidobacterium animalis ssp. animalis CCDM 218

Pacyga-Prus, K., Sandström, C., Šrůtková, D., Schwarzer, M., & Górska, S. (2024) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2024.122518 · Cited by 4

A neuroprotective effect of newly isolated probiotic bacterium Lactobacillus acidophilus SLAM_LAA02 in a rotenone-induced mouse model of Parkinson’s disease

Kim, Y., Seo, E., Kang, A., Kang, M.-G., Jang, K. B., Oh, S., & Kim, Y. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118896 · Cited by 3

Modulation of Gut Microbiota Through Dietary Fibers to Enhance Regulatory T Cell-Based Immunotherapy in GVHD Following Hematopoietic Stem Cell Transplantation

Asayesh, M., Nazarzadeh, A., Jamshidi, S., Keramat, S., Ryszkiel, I., & Stanek, A. (2026) · Nutrients · doi:10.3390/nu18081216 · Cited by 3

Effects of Bifidobacteria bifidum strains on 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced acute colitis and its potential mechanism

Qu, D., Feng, S., Li, M., Yu, L., Tian, F., Zhang, H., Chen, W., & Zhai, Q. (2023) · Food Bioscience · doi:10.1016/j.fbio.2023.102387 · Cited by 3

Nanomedicine at the Pulmonary Frontier: Immune-Centric Approaches for Respiratory Disease Treatment

Kaur, J. K., Sharma, A., Passi, G., Dey, P., Khajuria, A., Alajangi, H. K., Jaiswal, P. K., Barnwal, R. P., & Singh, G. (2024) · Immunological Investigations · doi:10.1080/08820139.2023.2298398 · Cited by 3

Gold digging: Searching for gut microbiota that enhances antitumor immunity

Hou, F., Pan, Z., Yang, R., Zhi, F., & Bi, Y. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30272 · Cited by 2

Characterization of Lactobacillus paracasei JSRL18-60 with probiotic properties as a starter in manufacturing fermented milk

Jeong, S.-J., Yang, H.-J., Ryu, M. S., Seo, J. W., & Jeong, D. (2021) · Korean Journal of Food Preservation · doi:10.11002/kjfp.2021.28.1.147 · Cited by 3

Characteristics of an In Vitro Mesenteric Lymph Node Cell Suspension Model and Its Possible Association with In Vivo Functional Evaluation

Feng, S., Li, J., Qu, D., Tian, F., Yu, L., Zhang, H., Chen, W., Zhao, J., & Zhai, Q. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23021003 · Cited by 3

Understanding the interaction between melatonin and bifidobacteria

Rizzo, S. M., Longhi, G., Tarracchini, C., Argentini, C., Viappiani, A., Bianchi, M. G., Bussolati, O., van Sinderen, D., Ventura, M., & Turroni, F. (2025) · Microbiome Research Reports · doi:10.20517/mrr.2025.10 · Cited by 2

Gut microbiota contributes to the maintenance of sublingually induced regulatory T cells and tolerance in mice

Winias, S., Bando, K., Temtanapat, B., Nakano, M., Saito, M., Sugawara, S., Komatsu, M., Hirayama, A., Fukuda, S., Abe, T., et al. (2025) · Allergology International · doi:10.1016/j.alit.2025.06.003 · Cited by 2

Gut Microbiota and Metabolite Changes Induced by Tacrolimus: Implications for Skin Transplant Immunology in Mice

Wang, J., Zhang, X., Cui, C., Li, M., Xie, Z., Yang, L., Ding, D., Li, X., & Zhao, M. (2025) · Journal of Inflammation Research · doi:10.2147/jir.s539452 · Cited by 2

Targeting gut microbiota to regulate the adaptive immune response in atherosclerosis

Giakomidi, D., Ishola, A., & Nus, M. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1502124 · Cited by 4

Treg cell tune-up

Fehervari, Z. T. (2018) · Nature Immunology · doi:10.1038/s41590-018-0271-3

Rationally Selected Probiotics as Immunomodulatory Biologics

IM, S. H. (2019) · Open Access System for Information Sharing (Pohang University of Science and Technology)

Bifidobacterium bifidum presents on the cell surface a complex mixture of glucans and galactans with different immunological properties

Speciale, I., Verma, R. P., Lorenzo, F. D., Molinaro, A., Im, S., & Castro, C. D. (2019) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2019.05.006 · Cited by 53

Immunomodulatory Effects of Bifidobacteria

岩淵, 紀., & 清水, 金. (2014) · バイオインダストリー

Capsular Polysaccharide of Bifidobacterium bifidum Induces Functional Regulatory T Cells

임신혁 (2016) · Open Access System for Information Sharing (Pohang University of Science and Technology)