The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Neuronal Growth Cone Retraction Relies on Proneurotrophin Receptor Signaling Through Rac
Open accessAbstract
Whereas NGF promotes neurite outgrowth, the precursor form proNGF triggers neurite retraction.
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“Pro-BDNF binding to p75NTR has also been shown to induce pruning of axons and dendrites85,88–91 and promote long-term depression (LTD)92–94.”
From Neuronal plasticity and neurotrophic factors in drug responses (2017) · cites this paper as [90]
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Cites
Lifeact: a versatile marker to visualize F-actin
Riedl, J., Crevenna, A. H., Kessenbrock, K., Yu, J. H., Neukirchen, D., Bista, M., Bradke, F., Jenne, D., Holak, T. A., Werb, Z., et al. (2008) · Nature Methods · doi:10.1038/nmeth.1220 · Cited by 2,189
Regulation of Cell Survival by Secreted Proneurotrophins
Lee, R., Kermani, P., Teng, K. K., & Hempstead, B. L. (2001) · Science · doi:10.1126/science.1065057 · Cited by 1,670
Self-citationFunctions of the neurotrophins during nervous system development: What the knockouts are teaching us
Snider, W. D. (1994) · Cell · doi:10.1016/0092-8674(94)90048-5 · Cited by 1,421
ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75NTRand Sortilin
Teng, H. K., Teng, K. K., Lee, R., Wright, S., Tevar, S., Almeida, R. D., Kermani, P., Torkin, R., Chen, Z.-Y., Lee, F. S., et al. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.5123-04.2005 · Cited by 1,013
Self-citationSortilin is essential for proNGF-induced neuronal cell death
Nykjaer, A., Lee, R., Teng, K. K., Jansen, P., Madsen, P., Nielsen, M. S., Jacobsen, C., Kliemannel, M., Schwarz, E., Willnow, T. E., et al. (2004) · Nature · doi:10.1038/nature02319 · Cited by 962
Self-citationNeurotrophins regulate dendritic growth in developing visual cortex
McAllister, A. K., Lo, D. C., & Katz, L. C. (1995) · Neuron · doi:10.1016/0896-6273(95)90171-x · Cited by 959
AXON RETRACTION AND DEGENERATION IN DEVELOPMENT AND DISEASE
Luo, L., & O’Leary, D. D. M. (2005) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.28.061604.135632 · Cited by 859
Brain‐derived neurotrophic factor and the development of structural neuronal connectivity
Cohen‐Cory, S., Kidane, A. H., Shirkey, N. J., & Marshak, S. (2010) · Developmental Neurobiology · doi:10.1002/dneu.20774 · Cited by 611
Neuronal Chemotaxis: Chick Dorsal-Root Axons Turn Toward High Concentrations of Nerve Growth Factor
Gundersen, R. W., & Barrett, J. N. (1979) · Science · doi:10.1126/science.493992 · Cited by 520
Role of fascin in filopodial protrusion
Vignjevic, D. M., Kojima, S.-I., Aratyn-Schaus, Y., Danciu, O. C., Svitkina, T., & Borisy, G. G. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200603013 · Cited by 485
Cited by
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Phillips, C. (2017) · Neural Plasticity · doi:10.1155/2017/7260130 · Cited by 480
The Role of BDNF on Neural Plasticity in Depression
Yang, T., Nie, Z., Shu, H., Kuang, Y., Chen, X., Cheng, J., Yu, S., & Liu, H. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00082 · Cited by 435
BDNF and Hippocampal Synaptic Plasticity
Leal, G., Bramham, C. R., & Duarte, C. B. (2017) · Vitamins and Hormones · doi:10.1016/bs.vh.2016.10.004 · Cited by 425
Brain-derived neurotrophic factor in mood disorders and antidepressant treatments
Castrén, E., & Kojima, M. (2017) · Neurobiology of Disease · doi:10.1016/j.nbd.2016.07.010 · Cited by 337
Yang, J., Harte‐Hargrove, L. C., Siao, C.-J., Marinic, T. E., Clarke, R., Ma, Q., Jing, D., LaFrancois, J. J., Bath, K. G., Mark, W. H., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.03.040 · Cited by 333
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Metadata
- Authors
- Deinhardt, K., Kim, T., Spellman, D. S., Mains, R. E., Eipper, B. A., Neubert, T. A., Chao, M. V., & Hempstead, B. L.
- Affiliations
- New York University (US)
- Weill Cornell Medicine (US)
- UConn Health (US)
- Corresponding author
- Kim, Taeho
- Hempstead, Barbara L.
- ORCID
- Venue
- Science Signaling
- Published
- 2011-12-06
- Volume
- 4
- Issue
- 202
- Pages
- ra82-ra82
- ISSN
- 1937-9145 (ISSN-L)
- 1945-0877
- PMC
- PMC3360552
- OpenAlex
- W2046114399
- Cited by
- 183
- References
- 42
- Citations by year
- 2026: 6 · 2025: 10 · 2024: 7 · 2023: 28 · 2022: 13 · 2021: 9 · 2020: 15 · 2019: 16 · 2018: 7 · 2017: 11 · 2016: 14 · 2015: 11 · 2014: 20 · 2013: 7 · 2012: 9
- FWCI
- 4.77
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Signaling (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- ePrints Soton (University of Southampton) (acceptedVersion)
- Funders
- National Institutes of Health (1s10rr017990-01)
- National Institute on Drug Abuse (R01DA015464, DA-15464)
- National Institute of Diabetes and Digestive and Kidney Diseases (DK-32948, R01DK032948, R56DK032948)
- National Institute of Neurological Disorders and Stroke (R01NS021072, R01NS064114, NS30687, NS-21072, R01NS030687, NS050276, P30NS050276, R56NS021072, NS64114)
- National Center for Research Resources (RR017990)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD-23315, P01HD023315)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Axon Guidance and Neuronal Signaling
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- proNGF, p75 neurotrophin receptor, SorCS2, sortilin, trios, Rac, fascin, actin dynamics, neuronal morphology, hippocampal neurons, axon guidance
- MeSH terms
- Actins, Animals, Carrier Proteins, Cell Line, Cells, Cultured, Humans, Microfilament Proteins, Models, Neurological, Nerve Tissue Proteins, Receptors, Cell Surface, Signal Transduction, Growth Cones, Guanine Nucleotide Exchange Factors, rac GTP-Binding Proteins, Receptor, Nerve Growth Factor, Mice, Rats
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