The DOI matches its Crossref record; 34 of the 35 references it cites were found in a registry or an index.
The Fate and Toxicity of Raman-Active Silica-Gold Nanoparticles in Mice
Open accessAbstract
Gold-core nanoparticles designed for imaging by Raman spectroscopy in patients are generally nontoxic in mice, causing only temporary liver inflammation when given intravenously.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A new mathematical model for relative quantification in real-time RT-PCR
Pfaffl, M. W. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.9.e45 · Cited by 34,610
Molecular imaging in living subjects: seeing fundamental biological processes in a new lightPreprint
Massoud, T. F., & Gambhir, S. S. (2003) · Genes & Development · doi:10.1101/gad.1047403 · Cited by 2,205
Self-citationLuminescent quantum dots for multiplexed biological detection and imaging
Chan, W. C. W., Maxwell, D. J., Gao, X., Bailey, R. E., Han, M., & Nie, S. (2002) · Current Opinion in Biotechnology · doi:10.1016/s0958-1669(02)00282-3 · Cited by 2,068
Size‐Dependent Cytotoxicity of Gold Nanoparticles
Pan, Y., Neuß, S., Leifert, A., Fischler, M., Wen, F., Simon, U., Schmid, G., Brandau, W., & Jahnen‐Dechent, W. (2007) · Small · doi:10.1002/smll.200700378 · Cited by 1,881
Molecular imaging of cancer with positron emission tomography
Gambhir, S. S. (2002) · Nature reviews. Cancer · doi:10.1038/nrc882 · Cited by 1,658
Self-citationPEGylated nanoparticles for biological and pharmaceutical applications
Otsuka, H., Nagasaki, Y., & Kataoka, K. (2003) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00226-0 · Cited by 1,619
Toxicity of Gold Nanoparticles Functionalized with Cationic and Anionic Side Chains
Goodman, C. M., McCusker, C. E., Yilmaz, T., & Rotello, V. M. (2004) · Bioconjugate Chemistry · doi:10.1021/bc049951i · Cited by 1,602
Prospects forin vivoRaman spectroscopy
Hanlon, E. B., Manoharan, R., Koo, T.-W., Shafer‐Peltier, K., Motz, J. T., Fitzmaurice, M., Kramer, J. R., Itzkan, I., Dasari, R. R., & Feld, M. S. (2000) · Physics in Medicine and Biology · doi:10.1088/0031-9155/45/2/201 · Cited by 906
Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death.
Korsmeyer, S. J., Shutter, J. R., Novack, D. V., Merry, D. E., & Oltvai, Z. N. (1993) · PubMed · Cited by 865
Rationally designed nanostructures for surface-enhanced Raman spectroscopy
Banholzer, M. J., Millstone, J. E., Qin, L., & Mirkin, C. A. (2008) · Chemical Society Reviews · doi:10.1039/b710915f · Cited by 795
Cited by
Sorted by citations
Nanomaterials for In Vivo Imaging
Smith, B. R., & Gambhir, S. S. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00073 · Cited by 1,084
Self-citationKircher, M. F., de la Zerda, A., Jokerst, J. V., Zavaleta, C. L., Kempen, P. J., Mittra, E., Pitter, K. L., Huang, R., Campos, C., Habte, F. G., et al. (2012) · Nature Medicine · doi:10.1038/nm.2721 · Cited by 1,074
Self-citationSERS Nanoparticles in Medicine: From Label-Free Detection to Spectroscopic Tagging
Lane, L. A., Qian, X., & Nie, S. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00265 · Cited by 881
Nanooncology: The future of cancer diagnosis and therapy
Thakor, A. S., & Gambhir, S. S. (2013) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21199 · Cited by 602
Self-citationHybrid Nanoparticles for Detection and Treatment of Cancer
Sailor, M. J., & Park, J. (2012) · Advanced Materials · doi:10.1002/adma.201200653 · Cited by 495
Metadata
- Authors
- Thakor, A. S., Luong, R., Paulmurugan, R., Lin, F. I., Kempen, P., Zavaleta, C., Chu, P., Massoud, T. F., Sinclair, R., & Gambhir, S. S.
- Affiliations
- University of Cambridge (GB)
- Stanford University (US)
- Stanford Medicine (US)
- Corresponding author
- Gambhir, Sanjiv S.
- ORCID
- Venue
- Science Translational Medicine
- Published
- 2011-04-20
- Volume
- 3
- Issue
- 79
- Pages
- 79ra33-79ra33
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC3873137
- OpenAlex
- W2099459454
- Semantic Scholar
- 8fd9649353de84ba2ee80b82b8ae3b10c09fc076
- Cited by
- 159
- References
- 35
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 5 · 2023: 2 · 2022: 11 · 2021: 12 · 2020: 8 · 2019: 11 · 2018: 14 · 2017: 13 · 2016: 10 · 2015: 15 · 2014: 13 · 2013: 15 · 2012: 13
- FWCI
- 6.13
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Cancer Institute (U54CA119367, P50CA114747, U54CA151459)
- Topics
- Physical Sciences › Materials Science › Electronic, Optical and Magnetic Materials › Gold and Silver Nanoparticles Synthesis and Applications
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Spectroscopy Techniques in Biomedical and Chemical Research
- Keywords
- surface-enhanced Raman scattering, PEGylated nanoparticles, acute toxicity, tissue distribution, reticuloendothelial system, macrophage clearance, oxidative stress, liver inflammation, rectal administration, colorectal cancer detection, affibody
- MeSH terms
- Animals, Female, Gold, Male, Polyethylene Glycols, Silicon Dioxide, Spectrum Analysis, Raman, Mice, Metal Nanoparticles
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review