Cited by 300Epilepsy research and treatmentNeuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cortical GABAergic excitation contributes to epileptic activities around human glioma

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Pallud, Johan, Le Van Quyen, Michel, Bielle, Franck, Pellegrino, Christophe, Varlet, Pascale, Labussiere, Marianne, Cresto, Noémie, Dieme, Marie-Joseph +9 more·2014·Science Translational Medicine

Abstract

Epileptic discharges in the neocortex surrounding human gliomas are initiated by GABAergic interneurons through alterations of chloride homeostasis in pyramidal cells.

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Crossref · 10.1126/scitranslmed.3008065

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63 of 63 references verified0 citation errors · 0 not checkable

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1 of the 64 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

  1. [3]Hirsch JF Buisson-Ferey J Sachs M Hirsch JC Scherrer J [Electrocorticogram and unitary activites with expanding lesions in man] Electroencephalogr Clin Neurophysiol 1966 21 417 428 4162773
  2. [7]Pallud J 2011 153 161 Springer Netherlands, Dordrecht

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Authors
Pallud, J., Le Van Quyen, M., Bielle, F., Pellegrino, C., Varlet, P., Labussiere, M., Cresto, N., Dieme, M.-J., Baulac, M., Duyckaerts, C., Kourdougli, N., Chazal, G., Devaux, B., Rivera, C., Miles, R., Capelle, L., & Huberfeld, G.
Affiliations
  • Centre National de la Recherche Scientifique (FR)
  • Sorbonne Universités, University Pierre and Marie Curie (UPMC) University of Paris 06, F-75005 Paris, France.
  • Sorbonne Université (FR)
  • Inserm (FR)
  • Sorbonne Paris Cité (FR)
  • Assistance Publique – Hôpitaux de Paris (FR)
  • University of Helsinki (FI)
Corresponding author
  • Bielle, Franck
  • Pellegrino, Christophe
  • Huberfeld, Gilles
Venue
Science Translational Medicine
Published
2014-07-09
Volume
6
Issue
244
Pages
244ra89-244ra89
ISSN
  • 1946-6234 (ISSN-L)
  • 1946-6242
OpenAlex
W2157338202
Cited by
300
References
64
Citations by year
2026: 15 · 2025: 24 · 2024: 32 · 2023: 35 · 2022: 34 · 2021: 25 · 2020: 18 · 2019: 28 · 2018: 26 · 2017: 22 · 2016: 23 · 2015: 14 · 2014: 4
FWCI
16.02
Type
journal article
Language
en
Open access
Locations
  • Science Translational Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Epilepsy research and treatment
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Keywords
glioma, epileptogenicity, chloride homeostasis, KCC2, NKCC1, interictal epileptiform discharges, pyramidal neurons, interneurons, excitatory-inhibitory imbalance
MeSH terms
Action Potentials, Brain Neoplasms, Chlorides, Epilepsy, gamma-Aminobutyric Acid, Glioma, Glutamates, Humans, Interneurons, Neocortex

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