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Cortical GABAergic excitation contributes to epileptic activities around human glioma
Open accessAbstract
Epileptic discharges in the neocortex surrounding human gliomas are initiated by GABAergic interneurons through alterations of chloride homeostasis in pyramidal cells.
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“The cellular and molecular changes underlying tumor-associated epilepsy collectively point to a decrease in GABAergic and increase in glutamatergic transmission as the major contributors3–6.”
From Perineuronal nets decrease membrane capacitance of peritumoral fast spiking interneurons in a model of epilepsy (2018) · cites this paper as [5]
In the citing paper
“the remaining GABAergic neurons show a significantly reduced inhibitory potential.”
From Perineuronal nets decrease membrane capacitance of peritumoral fast spiking interneurons in a model of epilepsy (2018) · cites this paper as [5]
In the citing paper
“Seizures originate from the PTC, and previous studies3,5,6 show altered excitation−inhibition balance in the PTC due to changes in glutamatergic and GABAergic activity.”
From Perineuronal nets decrease membrane capacitance of peritumoral fast spiking interneurons in a model of epilepsy (2018) · cites this paper as [5]
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1 retracted
Brain Tumor and Seizures: Pathophysiology and Its Implications for Treatment Revisited
Schaller, B. J., & Rüegg, S. J. (2003) · Epilepsia · doi:10.1046/j.1528-1157.2003.05203.x · Cited by 129
RetractedThe 2007 WHO Classification of Tumours of the Central Nervous System
Louis, D. N., Ohgaki, H., Wiestler, O. D., Cavenee, W. K., Burger, P. C., Jouvet, A., Scheithauer, B. W., & Kleihues, P. (2007) · Acta Neuropathologica · doi:10.1007/s00401-007-0243-4 · Cited by 15,675
Erratum to: The 2007 WHO classification of tumours of the central nervous system
Louis, D. N., Ohgaki, H., Wiestler, O. D., Cavenee, W. K., Burger, P. C., Jouvet, A., Scheithauer, B. W., & Kleihues, P. (2007) · Zurich Open Repository and Archive (University of Zurich) · doi:10.5167/uzh-156115 · Cited by 4,435
The K+/Cl− co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation
Rivera, C., Voipio, J., Payne, J. A., Ruusuvuori, E., Lahtinen, H., Lamsa, K., Pirvola, U., Saarma, M., & Kaila, K. (1999) · Nature · doi:10.1038/16697 · Cited by 2,152
Self-citationNKCC1 transporter facilitates seizures in the developing brain
Dzhala, V. I., Talos, D. M., Sdrulla, D., Brumback, A. C., Mathews, G. C., Benke, T. A., Delpire, E. J., Jensen, F. E., & Staley, K. J. (2005) · Nature Medicine · doi:10.1038/nm1301 · Cited by 1,004
On the Origin of Interictal Activity in Human Temporal Lobe Epilepsy in Vitro
Cohen, I., Navarro, V., Clémenceau, S., Baulac, M., & Miles, R. (2002) · Science · doi:10.1126/science.1076510 · Cited by 1,001
Self-citationEpilepsy in patients with brain tumours: epidemiology, mechanisms, and management
van Breemen, M. S. M., Wilms, E. B., & Vecht, C. J. (2007) · The Lancet Neurology · doi:10.1016/s1474-4422(07)70103-5 · Cited by 913
Staba, R. J., Wilson, C. L., Bragin, A., Fried, I., & Engel, J. (2002) · Journal of Neurophysiology · doi:10.1152/jn.2002.88.4.1743 · Cited by 666
Perturbed Chloride Homeostasis and GABAergic Signaling in Human Temporal Lobe Epilepsy
Huberfeld, G., Wittner, L., Clémenceau, S., Baulac, M., Kaila, K., Miles, R., & Rivera, C. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2761-07.2007 · Cited by 634
Self-citationGlutamate release promotes growth of malignant gliomas
Takano, T., Lin, J. H.-C., Arcuino, G., Gao, Q., Yang, J., & Nedergaard, M. (2001) · Nature Medicine · doi:10.1038/nm0901-1010 · Cited by 610
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Clasadonte, J., Morel, L., Barrios-Camacho, C. M., Chiang, M. S. R., Zhang, J., Iyer, L. K., Haydon, P. G., & Yang, Y. (2016) · Neurobiology of Disease · doi:10.1016/j.nbd.2016.03.024 · Cited by 20
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Huang, C. Y., Chi, X., Hu, X., Chen, N., Zhou, Q., Zhou, D., & Li, J. (2017) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2017.01.005 · Cited by 17
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Ruffolo, G., Cifelli, P., Miranda‐Lourenço, C., Felice, E. D., Limatola, C., Sebastião, A. M., Diógenes, M. J., Aronica, E., & Palma, E. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.06.015 · Cited by 13
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Morris, G., Avoli, M., Bernard, C., Connor, K., de Curtis, M., Dulla, C. G., Jefferys, J. G. R., Psarropoulou, C., Staley, K. J., & Cunningham, M. O. (2023) · Epilepsia · doi:10.1111/epi.17744 · Cited by 8
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Stakišaitis, D., Damanskienė, E., Curkūnavičiūtė, R., Juknevičienė, M., Alonso, M. M., Valančiūtė, A., Ročka, S., & Balnytė, I. (2021) · Dose-Response · doi:10.1177/1559325821990166 · Cited by 8
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Tobochnik, S. D., Bateman, L. M., Akman, Ç. I., Anbarasan, D., Bazil, C. W., Bell, M. W., Choi, H., Feldstein, N. A., Kent, P. F., McBrian, D. K., et al. (2021) · Journal of Clinical Neurophysiology · doi:10.1097/wnp.0000000000000833 · Cited by 7
Vychopen, M., Güresir, Á., Basaran, A. E., Güresir, E., & Wach, J. (2024) · Neurosurgical Review · doi:10.1007/s10143-024-03137-x · Cited by 9
Localization of the Epileptogenic Zone Using Neural Spatial Volatility in Epilepsy Surgery
Kuroda, N., Uda, H., Inoue, K., Kitazawa, Y., Osawa, S., Nemoto, H., Ishida, M., Ukishiro, K., Luat, A. F., Endo, H., et al. (2025) · Neurology · doi:10.1212/wnl.0000000000213906 · Cited by 7
Treatment of epilepsy associated with primary and metastatic brain tumors
Лебедева, А. В., Бурд, С. Г., Vlasov, P. N., Ермоленко, Н. А., Жидкова, И. А., Zyryanov, S. K., Kovaleva, I. Y., Насхлеташвили, Д. Р., Perunova, N. Y., Рудакова, И. Г., et al. (2021) · Epilepsy and Paroxysmal Conditions · doi:10.17749/2077-8333/epi.par.con.2021.099 · Cited by 7
Boussen, S., Velly, L. J., Bénar, C., Métellus, P., Bruder, N. J., & Trébuchon, A. (2016) · Brain Topography · doi:10.1007/s10548-016-0502-6 · Cited by 16
Kumar, K., Dixit, A. B., Tripathi, M., Dubey, V., Siraj, F., Sharma, M. C., Lalwani, S., Chandra, P. S., & Banerjee, J. (2022) · Functional & Integrative Genomics · doi:10.1007/s10142-022-00869-1 · Cited by 7
Straumann, S., Schaft, E. V., Noordmans, H. J., Dankbaar, J. W., Otte, W. M., van Steenis, J. L., Smits, P. L., Zweiphenning, W. J. E. M., van Eijsden, P., Gebbink, T. A., et al. (2022) · Brain Communications · doi:10.1093/braincomms/fcac302 · Cited by 7
Tescarollo, F. C., Valdivia, D. J., Chen, S. C., & Sun, H. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1268311 · Cited by 6
Structural and material basis of neuron–glioma interactions
Wang, J., Shen, T.-H., Liu, J., Wen, Q., Yang, X., Deng, Y., Duan, J., & Yu, S. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.217843 · Cited by 7
Enhancing KCC2 function reduces interictal activity and prevents seizures in temporal lobe epilepsy
Donneger, F., Zanin, A., Besson, J., Roussel, D., Kadiri, Y., Pagan, C., Sinha, M., David, N., Russeau, M., Bielle, F., et al. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2522722123 · Cited by 6
Self-citationA new bio-inspired stimulator to suppress hyper-synchronized neural firing in a cortical network
Amiri, M., Amiri, M., Nazari, S., & Karim Faez, A. (2016) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2016.09.007 · Cited by 6
Chen, G., Zhang, Y., Zheng, S., Xu, Y., Lin, P., Shang‐Guan, H., Lin, Y., Kang, D., & Yao, P. (2023) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2023.11952 · Cited by 6
AMPAR-mediated Interictal Discharges in Neurons of Entorhinal Cortex: Experiment and Model
Chizhov, A. V., Amakhin, D. V., Zaizev, A. V., & Magazanik, L. G. (2018) · Doklady Biological Sciences · doi:10.1134/s0012496618020011 · Cited by 6
Dey, S., Doddamani, R. S., Dixit, A. B., Tripathi, M., Sharma, M. C., Chandra, P. S., & Banerjee, J. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.689769 · Cited by 6
Seizures as Complications in Cancer
Benit, C. P., Kerkhof, M., Durán-Peña, A., & Vecht, C. J. (2017) · Springer eBooks · doi:10.1007/978-3-319-57901-6_9 · Cited by 6
Tumor‐related epilepsy in glioma: A multidisciplinary overview
Michelucci, R., Pauletto, G., Silvani, A., Pasini, E., Ius, T., Martinoni, M., Castioni, C. A., Salmaggi, A., Asioli, S., Maschio, M. C. E., et al. (2025) · Epilepsia · doi:10.1111/epi.18523 · Cited by 8
Spalletti, C., Scalera, M., Mori, E., Haddad, S., Mainardi, M., Cangi, D., Pillai, V., Parmigiani, E., Landi, S., Caleo, M., et al. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.106997 · Cited by 7
Zhang, J., Gong, L., Zhu, H., Sun, W., Tian, J., Zhang, Y., Liu, Q., Li, X., Zhang, F., Wang, S., et al. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106344 · Cited by 5
The molecular landscape of glioblastoma-associated epilepsy
Scheffel, T. B., Diz, F. M., Wieck, A., Begnini, K. R., & da Costa, J. C. (2025) · Journal of Molecular Medicine · doi:10.1007/s00109-025-02567-4 · Cited by 6
Damanskienė, E., Balnytė, I., Valančiūtė, A., Lesauskaitė, V., Alonso, M. M., & Stakišaitis, D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231810455 · Cited by 5
Bouwen, B. L. J., Bolleboom, A., Tang, Y., Yu, Z., van der Stap, A., van Rij, J. A., van Dis, V., Dirven, C. M. F., Zeeuw, C. I. D., van Tellingen, O., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-66226-5 · Cited by 4
Non-monotonic effects of GABAergic synaptic inputs on neuronal firing
Zadeh, A. A., Turner, B. D., Calakos, N., & Brunel, N. (2022) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1010226 · Cited by 4
Metadata
- Authors
- Pallud, J., Le Van Quyen, M., Bielle, F., Pellegrino, C., Varlet, P., Labussiere, M., Cresto, N., Dieme, M.-J., Baulac, M., Duyckaerts, C., Kourdougli, N., Chazal, G., Devaux, B., Rivera, C., Miles, R., Capelle, L., & Huberfeld, G.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Sorbonne Universités, University Pierre and Marie Curie (UPMC) University of Paris 06, F-75005 Paris, France.
- Sorbonne Université (FR)
- Inserm (FR)
- Sorbonne Paris Cité (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- University of Helsinki (FI)
- Corresponding author
- Bielle, Franck
- Pellegrino, Christophe
- Huberfeld, Gilles
- ORCID
- Venue
- Science Translational Medicine
- Published
- 2014-07-09
- Volume
- 6
- Issue
- 244
- Pages
- 244ra89-244ra89
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC4409113
- OpenAlex
- W2157338202
- Cited by
- 300
- References
- 64
- Citations by year
- 2026: 15 · 2025: 24 · 2024: 32 · 2023: 35 · 2022: 34 · 2021: 25 · 2020: 18 · 2019: 28 · 2018: 26 · 2017: 22 · 2016: 23 · 2015: 14 · 2014: 4
- FWCI
- 16.02
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- glioma, epileptogenicity, chloride homeostasis, KCC2, NKCC1, interictal epileptiform discharges, pyramidal neurons, interneurons, excitatory-inhibitory imbalance
- MeSH terms
- Action Potentials, Brain Neoplasms, Chlorides, Epilepsy, gamma-Aminobutyric Acid, Glioma, Glutamates, Humans, Interneurons, Neocortex
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