The DOI matches its Crossref record; 46 of the 47 references it cites were found in a registry or an index.
Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis
Open accessAbstract
The estrogen-dependent inflammatory and neuroangiogenic activities that drive endometriosis can be suppressed by estrogen receptor ligands in mice.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“ESR2 ligands acting as estrogen antagonists in endometriotic tissue show promising results in murine models and should also be considered as potential therapeutics (Zhao et al., 2015).”
From Endometriosis and nuclear receptors (2019) · cites this paper as Zhao et al., 2015
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Giudice, L. C., & Kao, L. C. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17403-5 · Cited by 3,166
Bulun, S. E. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0804690 · Cited by 1,772
Dupont, S., Krust, A., Gansmuller, A., Dierich, A., Chambon, P., & Mark, M. (2000) · Development · doi:10.1242/dev.127.19.4277 · Cited by 1,064
McLaren, J. F., Prentice, A., Jones, D. S., Millican, S. A., Müller, K. H., Sharkey, A., & Smith, S. K. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118815 · Cited by 499
Bacci, M., Capobianco, A., Monno, A., Cottone, L., Di Puppo, F., Camisa, B., Mariani, M., Brignole, C., Ponzoni, M., Ferrari, S., et al. (2009) · The American Journal of Pathology · doi:10.2353/ajpath.2009.081011 · Cited by 458
Berkley, K. J., Rapkin, A. J., & Papka, R. E. (2005) · Science · doi:10.1126/science.1111445 · Cited by 455
Role of Estrogen Receptor-β in Endometriosis
Bulun, S., Monsavais, D., Pavone, M., Dyson, M., Xue, Q., Attar, E., Tokunaga, H., & Su, E. (2012) · Seminars in Reproductive Medicine · doi:10.1055/s-0031-1299596 · Cited by 321
Anaf, V., Simon, P., El Nakadi, I., Fayt, I., Simonart, T., Buxant, F., & Noel, J.-C. (2002) · Human Reproduction · doi:10.1093/humrep/17.7.1895 · Cited by 317
An ADIOL-ERβ-CtBP Transrepression Pathway Negatively Regulates Microglia-Mediated Inflammation
Saijo, K., Collier, J. G., Li, A. C., Katzenellenbogen, J. A., & Glass, C. K. (2011) · Cell · doi:10.1016/j.cell.2011.03.050 · Cited by 295
Self-citationEndometriosis: hormone regulation and clinical consequences of chemotaxis and apoptosis
dos Reis, F. M., Petraglia, F., & Taylor, R. N. (2013) · Human Reproduction Update · doi:10.1093/humupd/dmt010 · Cited by 273
Self-citation
Flagged first, then by citations
1 of the 47 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- 10.1096/fj.10.163428 · DOI
Cited by
Sorted by citations
Items 101–171 of 171
Molecular mechanisms of and risk factors for endometriosis
Ponomarenko, I., Polonikov, A., & Churnosov, M. I. (2019) · Akusherstvo i ginekologiia · doi:10.18565/aig.2019.3.26-31 · Cited by 14
Microbiota insights in endometriosis
Parpex, G., Nicco, C., Chassaing, B., Santulli, P., Chouzenoux, S., Bourdon, M., Maignien, C., Doridot, L., Batteux, F., Chapron, C., et al. (2025) · Microbiome · doi:10.1186/s40168-025-02243-2 · Cited by 13
AURKA Enhances the Glycolysis and Development of Ovarian Endometriosis Through ERβ
Sun, Y., Zhang, S., Zhang, X., Li, G., Sun, F., Wang, M., Ren, C., Jiang, A., & Yang, T. (2024) · Endocrinology · doi:10.1210/endocr/bqae018 · Cited by 13
The long road of drug development for endometriosis – Pains, gains, and hopes
Liao, Z., Monsivais, D., & Matzuk, M. M. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.10.036 · Cited by 16
Zhao, J., Ma, W., Chen, W., Gao, J., Li, C., Tong, Y., Zhou, Q., Zhao, X., Wang, M., Xiao, H., et al. (2019) · Animal Cells and Systems · doi:10.1080/19768354.2019.1691052 · Cited by 13
He, Y., Xiong, T., Guo, F., Du, Z., Fan, Y., Sun, H., Zuohua, F., & Zhang, G. (2020) · Molecular Human Reproduction · doi:10.1093/molehr/gaaa014 · Cited by 13
Deng, L., Chen, C., Wu, J., Wang, C., Zhou, H., & Huang, J. (2017) · Neurochemical Research · doi:10.1007/s11064-017-2237-5 · Cited by 13
Schmitz, C. R., Oehninger, S., Genro, V. K., Chandra, N., Lattanzio, F. A., Yu, L., & Cunha‐Filho, J. S. (2017) · JBRA · doi:10.5935/1518-0557.20170056 · Cited by 13
Lee, S. Y., Lee, Y. Y., Choi, J. S., Yoon, M., & Han, J. (2016) · FEBS Journal · doi:10.1111/febs.13914 · Cited by 13
Khine, Y. M., Taniguchi, F., Nagira, K., Nakamura, K., Ohbayashi, T., Osaki, M., & Harada, T. (2018) · American Journal of Reproductive Immunology · doi:10.1111/aji.13023 · Cited by 11
Wu, L., Lan, D.-T., Sun, B., Su, R. J., Pei, F., Kuang, Z., Su, Y., Lin, S., Wang, X., Zhang, S., et al. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118659 · Cited by 12
SULFATION PATHWAYS: Contribution of intracrine oestrogens to the aetiology of endometriosis
Piccinato, C. D. A., Malvezzi, H., Gibson, D. A., & Saunders, P. T. K. (2018) · Journal of Molecular Endocrinology · doi:10.1530/jme-17-0297 · Cited by 12
Werner, F., Jasinski, V., Velho, R. V., Sehouli, J., & Mechsner, S. (2025) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-025-08019-1 · Cited by 11
Xie, Y., Kong, W., Zhao, X., LUO, D., Chen, S., ZHANG, H., & Ran, Y. (2023) · In Vivo · doi:10.21873/invivo.13356 · Cited by 10
Li, Y., Zhu, J., & Tang, J. Y. (2023) · Drug Design Development and Therapy · doi:10.2147/dddt.s392500 · Cited by 10
VINCI, G., Arkwright, S., Audebourg, A., Radenen, B., Chapron, C., Borghese, B., Dousset, B. E., Méhats, C., Vaiman, D., Vacher‐Lavenu, M., et al. (2016) · Reproductive Sciences · doi:10.1177/1933719116638188 · Cited by 10
Analysis of astaxanthin molecular targets based on network pharmacological strategies
Lin, Z. Y., Li, F., Zhang, Y., Tan, X., Luo, P., & Liu, H. (2021) · Journal of Food Biochemistry · doi:10.1111/jfbc.13717 · Cited by 10
Li, B., Qi, J., Cao, Y., Long, Y., Wei, Z., Wang, W., Hu, S., Wang, Y., Zhu, Q., Hu, X. J., et al. (2025) · Advanced Science · doi:10.1002/advs.202411752 · Cited by 10
Physiological and Pathological Roles of Estrogen Receptor
Korach, K. S., Hewitt, S. C., Hamilton, K. J., Li, Y., Ramsey, J. T., Garcia, M., Mathura, E., & Arao, Y. (2018) · Cancer drug discovery and develogment/Cancer drug discovery and development · doi:10.1007/978-3-319-99350-8_2 · Cited by 10
Self-citationZhou, H., Zhang, Q., & Qi, C. (2018) · Molecular Therapy — Oncolytics · doi:10.1016/j.omto.2018.11.001 · Cited by 9
Future Directions in Endometriosis Research and Therapeutics
Nothnick, W. B., Marsh, C. A., & Alali, Z. (2018) · Current Women s Health Reviews · doi:10.2174/1573404813666161221164810 · Cited by 9
Kastrati, I., Siklos, M. I., Brovkovych, S. D., Thatcher, G. R. J., & Frasor, J. M. (2017) · Hormones and Cancer · doi:10.1007/s12672-017-0294-5 · Cited by 9
Molecular Biology of Endometriosis
Sengupta, J., Geethadevi, A., Bhat, M. A., & Ghosh, D. (2016) · Human Reproduction · doi:10.1002/9781118849613.ch3 · Cited by 10
Broadening horizons: microbiota as a novel biomarker and potential treatment for endometriosis
Wang, M., Liu, W., Zheng, L., Ma, S., Jin, L., Zhao, D., & Li, D. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1521216 · Cited by 14
Khan, K. N., de Ziegler, D., & Guo, S. (2024) · Human Reproduction · doi:10.1093/humrep/deae006 · Cited by 7
Personalized therapy in endometriosis — based on ERα or ERβ expression
Zhan, L., & Cao, Y. (2024) · BMC Medicine · doi:10.1186/s12916-024-03415-x · Cited by 8
Захаренко, Н. Ф., Tatskyy, O. F., & Konovalenko, S. V. (2020) · Journal of Gynecology and Obstetrics · doi:10.11648/j.jgo.20200805.14 · Cited by 7
Sun, Y., Cai, J., Ding, S., & Bao, S. (2022) · Reproductive Sciences · doi:10.1007/s43032-022-01102-x · Cited by 7
Recent Trends in Medical Management of Endometriosis
Patel, M. (2024) · The Journal of Obstetrics and Gynecology of India · doi:10.1007/s13224-024-02097-y · Cited by 10
Repurposing ospemifene for potentiating an antigen-specific immune response
Kao, C.-J., Wurz, G. T., Lin, Y.-C., Vang, D. P., Phong, B., & DeGregorio, M. W. (2016) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000000776 · Cited by 5
Liao, Z., Li, J., Xian, S., Huang, J., Tian, W., Zhong, Q., Shi, W., Li, X. F., Shuai, X., & Chen, S. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.10.054 · Cited by 5
Lin, T.-C., Wang, K., Chuang, K., Kao, A., & Kuo, T. (2024) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2024.01.012 · Cited by 4
Aberrant invasion of nervous fibers in endometriosis: the role of estrogens
Бурлев, В. А. (2020) · Russian Journal of Human Reproduction · doi:10.17116/repro202026021104 · Cited by 6
Klepcová, Z., Špaková, I., Madreiter‐Sokolowski, C. T., Graier, W. F., Kalinová, K., Samoľová, E., Smolková, R., Smolko, L., & Rabajdová, M. (2023) · New Journal of Chemistry · doi:10.1039/d3nj00412k · Cited by 3
Lu, A., Lin, S., Li, J., Luo, H., Lu, C., Wang, Y., Cao, Y., Cao, X., Peng, J., Zhang, J., et al. (2025) · Human Reproduction · doi:10.1093/humrep/deaf130 · Cited by 4
Immunologic Aspects of Endometriosis
Young, A. N., Maghsoudlou, P., King, L. P., Rogers, M. S., & Hornstein, M. D. (2024) · Current Obstetrics and Gynecology Reports · doi:10.1007/s13669-024-00373-2 · Cited by 3
Wu, L., Su, R., Jia, J., Kuang, Z., Zeng, C., & Pei, F. (2026) · Hereditas · doi:10.1186/s41065-026-00637-2 · Cited by 2
Endometriosis and Endometriosis-Associated Tumors
Simmen, R. C. M., Quick, C. M., & Zheng, W. (2024) · Springer eBooks · doi:10.1007/978-981-19-7696-4_12-1 · Cited by 2
Quality of life of endometriosis patients: focus on pain syndrome and neurological disorders
Lunko, T. A., Chaika, H. V., Konovalenko, S. V., & Lunko, A. S. (2025) · INTERNATIONAL NEUROLOGICAL JOURNAL · doi:10.22141/2224-0713.21.2.2025.1162 · Cited by 2
Endometriosis: Bright future for a cloudy past?
Nothnick, W. B. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aaa5075 · Cited by 2
Osuji-kalu, N. C., C., E. A., & Chukwudoruo, C. S. (2024) · African Journal of Biology and Medical Research · doi:10.52589/ajbmr-wnxgcvpm · Cited by 2
Comparison of The Efficacy of Letrozole Versus Danazol in Pain Relief in Endometriosis
Nawaz, S., Habib, S., Ayoub, S., Shams, G., Naeem, N., & Sultana, R. (2022) · Pakistan Journal of Health Sciences · doi:10.54393/pjhs.v3i06.345 · Cited by 1
DESIGN, DEVELOPMENT, AND CHARACTERIZATION OF CURCUMIN-LOADED NANO TABLET IN ENDOMETRIOSIS TREATMENT
ABHINI, U., Mariappan, G., & Kumar, B. (2025) · International Journal of Applied Pharmaceutics · doi:10.22159/ijap.2025v17i1.52533 · Cited by 1
Yarmolinskaya, M. I., & Zakuraeva, K. А. (2025) · Journal of obstetrics and women s diseases · doi:10.17816/jowd688923 · Cited by 1
Shi, W., Wang, M., Jin, Z., Chen, X., Li, J., Lai, H., Li, X. F., Zhong, Q., Chen, Y., & Chen, S. (2026) · Journal of Pain Research · doi:10.2147/jpr.s557430 · Cited by 1
Self-citationTranscription factor addictions: exploring the potential Achilles’ Heel of endometriosis
Yang, Y., Du, Y., Ma, X., Yuan, G., Li, G., Zhang, Q., & Zhou, S. (2025) · Science China Life Sciences · doi:10.1007/s11427-024-2832-8 · Cited by 1
Integrative analysis reveals ferroptosis-related genes with RRM2 as a key driver in endometriosis
Zhong, L., Niu, Y., Ma, R., Luo, Y., Li, X., Wang, Q., Xu, H., & Kang, X. (2025) · Gene · doi:10.1016/j.gene.2025.149754 · Cited by 1
The role of oxidation-sensitive nociception and epigenetics in endometriosis-associated pain
Wright, K. R. (2017) · Cited by 1
Elevated phosphorylation of estrogen receptor α at serine-118 in ovarian endometrioma
Sun, H. J., Hirata, T., Koga, K., Arakawa, T., Nagashima, N., Neriishi, K., Elsherbini, M., Maki, E., Izumi, G., Harada, M., et al. (2022) · F&S Science · doi:10.1016/j.xfss.2022.04.004 · Cited by 1
Suppressing the oestrogen-inflammatory axis
Crunkhorn, S. (2015) · Nature Reviews Drug Discovery · doi:10.1038/nrd4576
Schubert, C. (2015) · Biology of Reproduction · doi:10.1095/biolreprod.115.128496
Endometriosis and Endometriosis-Associated Tumors
Simmen, R. C. M., Quick, C. M., Kelley, A. S., & Zheng, W. (2019) · Springer eBooks · doi:10.1007/978-981-13-3019-3_12
Педаченко, Н. Ю., Shemelko, T. L., & Тухтарян, Р. А. (2020) · Journal of Education Health and Sport · doi:10.12775/jehs.2020.10.05.034
Tratamento farmacológico para endometriose
Santos, C. M. D. N., Monte, L. E. M., Neto, J. C. P., da Silva, H. J. N., de Melo, A. F. M., Borges, S. H. A. L., Sousa, A. C. M., de Oliveira, J. C., Santana, F. D. S., Marinho, A. L. D. S., et al. (2021) · Research Society and Development · doi:10.33448/rsd-v10i7.16104 · Cited by 1
The roles and functions of macrophages in endometriosis
Jiao, X., Ji, M., Guo, S., & Wang, G. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820661-4.00007-8
Endometriosis Research: From Bench to Bedside
Laganà, A. S., & La Rosa, V. L. (2022) · MDPI eBooks · doi:10.3390/books978-3-0365-2798-7
Potential role of stem cells in the pathogenesis of endometriosis
Iyshwarya, B. K., Veerabathiran, R., & Sivamani, G. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-18800-8.00002-2
Endometriosis and Endometriosis-Associated Tumors
Simmen, R. C. M., Quick, C. M., & Zheng, W. (2025) · Springer eBooks · doi:10.1007/978-981-97-4822-8_12
Marla, S., Mortlock, S., Heinosalo, T., POUTANEN, M. H., Montgomery, G. W., & McKinnon, B. D. (2024) · Figshare · doi:10.6084/m9.figshare.26644399
Advances in the Role of Endometrial Microbiota Alterations in the Pathogenesis of Endometriosis
Xu, Z., Guo, W., & Shen, Y. (2026) · Reproductive Sciences · doi:10.1007/s43032-026-02050-6
Jeljeli, M. M. (2020) · theses.fr (ABES) · doi:10.70675/dfc4dd10z9fb4z4e16z836dz778a7ef9d1c1
Jameel, S., Zeenat, F., Ahmad, S., & Mustafa, S. (2026) · Hippocratic Journal of Unani Medicine · doi:10.4103/hjum.hjum_8_24
Morphological modulation of ovarian endometrioma with elagolix: a case report
Maladkar, M. N., Patani, N., Tekchandani, C. M., & Patil, R. (2026) · International Journal of Reproduction Contraception Obstetrics and Gynecology · doi:10.18203/2320-1770.ijrcog20261297
Molecular Insights Into Endometriosis for Early Detection and Therapeutic Targets
Kuai, M., Li, B., Shi, Z., 黄庆通, Pan, Y., Tang, M., Gao, X., Fang, J., & Lü, P. (2026) · Reproductive Sciences · doi:10.1007/s43032-026-02124-5
Zhang, Y., Wang, Q., Wang, X. L., Yang, S., Yu, G., Yang, D., & Wu, X. (2026) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2026.122108
Steroidal alkaloids as multi-target therapeutics for the treatment of endometriosis
Shirodkar, S., & Doshi, G. (2026) · Steroids · doi:10.1016/j.steroids.2026.109827
Zioło, K., Zarzycka, W., Skrzypek, J., Fidut, N., Szyprowski, K., Kisielewski, M., Wawerska, J., Wrzosek, W., Zugaj, M., & Okliński, B. (2026) · International Journal of Innovative Technologies in Social Science · doi:10.31435/ijitss.2(50).2026.5695
Nacoulma, A. P., Kambou, S. P., Ouédraogo, L., Lankouande, P. R., Meda, N. R., & Sakandé, J. (2026) · American Journal of Plant Sciences · doi:10.4236/ajps.2026.1710060
Metadata
- Authors
- Zhao, Y., Gong, P., Chen, Y., Nwachukwu, J. C., Srinivasan, S., Ko, C., Bagchi, M. K., Taylor, R. N., Korach, K. S., Nettles, K. W., Katzenellenbogen, J. A., & Katzenellenbogen, B. S.
- Affiliations
- University of Illinois Urbana-Champaign (US)
- Scripps Research Institute (US)
- Wake Forest University Health Sciences (US)
- National Institute of Environmental Health Sciences (US)
- Corresponding author
- Katzenellenbogen, Benita S.
- ORCID
- Venue
- Science Translational Medicine
- Published
- 2015-01-21
- Volume
- 7
- Issue
- 271
- Pages
- 271ra9-271ra9
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC4790140
- OpenAlex
- W2152982261
- Cited by
- 170
- References
- 47
- Citations by year
- 2026: 10 · 2025: 16 · 2024: 18 · 2023: 11 · 2022: 14 · 2021: 9 · 2020: 15 · 2019: 17 · 2018: 18 · 2017: 12 · 2016: 19 · 2015: 11
- FWCI
- 22.82
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIH (U54 HD055787, PHS 5R01DK015556, 5R01DK077085)
- Frenchman's Creek Women for Cancer Research
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
- Keywords
- endometriosis, estrogen receptor ligands, estrogen receptor alpha, estrogen receptor beta, anti-inflammatory activity, angiogenesis, neurogenesis, endometriotic stromal cells, fertility preservation
- MeSH terms
- Letrozole, Animals, Anti-Inflammatory Agents, Cell Survival, Cells, Cultured, Disease Models, Animal, Drug Therapy, Combination, Endometriosis, Estrogens, Female, Fertility, Humans, Indazoles, Inflammation, Ligands, Macrophages, Mice, Inbred C57BL, Mice, Transgenic, Neurons, Nitriles, Receptors, Estrogen, Triazoles, Treatment Outcome, Stromal Cells, Disease Progression, Embryonic Stem Cells
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
