The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice
Open accessAbstract
A microRNA-based therapeutic approach could be used to promote cardiac regeneration through the transient activation of cardiomyocyte proliferation.
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“Recent pre-clinical evidence indicates that Hippo pathway inhibiting miRNAs can stimulate CM proliferation34,57,58.”
From 3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels (2021) · cites this paper as [57]
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Cites
1 retracted
Nagalingam, R. S., Sundaresan, N. R., Noor, M., Gupta, M. P., Solaro, R. J., & Gupta, M. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.580977 · Cited by 43
RetractedMicroRNA targets in Drosophila
Enright, A. J., John, B., Gaul, U., Tuschl, T., Sander, C., & Marks, D. S. (2003) · Genome Biology · doi:10.1186/gb-2003-5-1-r1 · Cited by 3,597
Transient Regenerative Potential of the Neonatal Mouse Heart
Porrello, E. R., Mahmoud, A. I., Simpson, E., Hill, J. A., Richardson, J. A., Olson, E. N., & Sadek, H. A. (2011) · Science · doi:10.1126/science.1200708 · Cited by 2,545
Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps
Chi, S. W., Zang, J. B., Mele, A., & Darnell, R. B. (2009) · Nature · doi:10.1038/nature08170 · Cited by 1,791
Mammalian heart renewal by pre-existing cardiomyocytes
Senyo, S. E., Steinhauser, M. L., Pizzimenti, C. L., Yang, V. K., Cai, L., Wang, M., Wu, T.-D., Guerquin-Kern, J.-L., Lechene, C. P., & Lee, R. T. (2013) · Nature · doi:10.1038/nature11682 · Cited by 1,343
Laflamme, M. A., & Murry, C. E. (2011) · Nature · doi:10.1038/nature10147 · Cited by 1,272
Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency
Anokye‐Danso, F., Trivedi, C. M., Juhr, D., Gupta, M., Cui, Z., Tian, Y., Zhang, Y., Yang, W., Gruber, P. J., Epstein, J. A., et al. (2011) · Cell stem cell · doi:10.1016/j.stem.2011.03.001 · Cited by 1,248
Self-citationHippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size
Heallen, T. R., Zhang, M., Wang, J., Bonilla-Claudio, M., Klysik, E., Johnson, R. L., & Martin, J. F. (2011) · Science · doi:10.1126/science.1199010 · Cited by 1,092
Functional screening identifies miRNAs inducing cardiac regeneration
Eulalio, A., Mano, M., Ferro, M. D., Zentilin, L., Sinagra, G., Zacchigna, S., & Giacca, M. (2012) · Nature · doi:10.1038/nature11739 · Cited by 1,029
A Highly Efficient Recombineering-Based Method for Generating Conditional Knockout MutationsPreprint
Liu, P., Jenkins, N. A., & Copeland, N. G. (2003) · Genome Research · doi:10.1101/gr.749203 · Cited by 1,013
Cited by
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Signaling pathways and targeted therapy for myocardial infarction
Zhang, Q., Wang, L., Wang, S., Cheng, H., Xu, L., Pei, G., Wang, Y., Fu, C., Jiang, Y., He, C., et al. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-00925-z · Cited by 882
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration
Mohamed, T., Ang, Y.-S., Radzinsky, E., Zhou, P., Huang, Y., Elfenbein, A., Foley, A., Magnitsky, S. G., & Srivastava, D. (2018) · Cell · doi:10.1016/j.cell.2018.02.014 · Cited by 582
Daly, A. C., Davidson, M. D., & Burdick, J. A. (2021) · Nature Communications · doi:10.1038/s41467-021-21029-2 · Cited by 470
Therapeutic approaches for cardiac regeneration and repair
Hashimoto, H., Olson, E. N., & Bassel‐Duby, R. (2018) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0036-6 · Cited by 428
Cardiomyocyte Regeneration: A Consensus Statement.
Eschenhagen, T., Bolli, R., Braun, T. W., Field, L. J., Fleischmann, B. K., Frisén, J., Giacca, M., Hare, J. M., Houser, S. R., Lee, R. T., et al. (2017) · PubMed · doi:10.1161/circulationaha.117.029343 · Cited by 397
Metadata
- Authors
- Tian, Y., Liu, Y., Wang, T., Zhou, N., Kong, J., Chen, L., Snitow, M., Morley, M., Li, D., Petrenko, N., Zhou, S., Lu, M., Gao, E., Koch, W. J., Stewart, K. M., & Morrisey, E. E.
- Affiliations
- University of Pennsylvania (US)
- Tang Du Hospital (CN)
- Temple University (US)
- Corresponding author
- Tian, Ying
- Morrisey, Edward E.
- ORCID
- Venue
- Science Translational Medicine
- Published
- 2015-03-18
- Volume
- 7
- Issue
- 279
- Pages
- 279ra38-279ra38
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC6295313
- OpenAlex
- W2140775408
- Cited by
- 381
- References
- 42
- Citations by year
- 2026: 10 · 2025: 27 · 2024: 36 · 2023: 36 · 2022: 35 · 2021: 43 · 2020: 45 · 2019: 41 · 2018: 28 · 2017: 40 · 2016: 26 · 2015: 14
- FWCI
- 15.54
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIH (R01-HL064632, R01-HL087825, U01-HL100405, K99/R00-HL111348)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
- Keywords
- cardiomyocyte proliferation, cardiac regeneration, Hippo signaling pathway, myocardial infarction, myocardial fibrosis, cardiomyocyte dedifferentiation, miRNA-based therapy, cardiac repair, cell cycle re-entry, heart development
- MeSH terms
- Hippo Signaling Pathway, Alleles, Animals, Cell Cycle, Cell Separation, Cells, Cultured, Flow Cytometry, Heart, Humans, Lipids, Male, Myocardial Infarction, Regeneration, Signal Transduction, Lentivirus, Protein Serine-Threonine Kinases, Myocytes, Cardiac, MicroRNAs, Cell Proliferation, Mice, HEK293 Cells
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