The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Single-cell genotyping demonstrates complex clonal diversity in acute myeloid leukemia
Abstract
The targeted genotyping of single acute myeloid leukemia cells is technically feasible, identifies the zygosities of concurrent mutations, and suggests that sequencing of bulk populations may underestimate clonal complexity.
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“The serial acquisition of driver genetic mutations and chromosomal aberrations in these cancer-initiating clones have been reported in significant detail in several recent studies [205][206][207][208] .”
From Clonal haematopoiesis and dysregulation of the immune system (2023) · cites this paper as [207]
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Cites
Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
Gerlinger, M., Rowan, A. J., Horswell, S., Larkin, J., Endesfelder, D., Gronroos, E., Martinez, P., Matthews, N., Stewart, A., Tarpey, P., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1113205 · Cited by 7,774
Greaves, M., & Maley, C. C. (2012) · Nature · doi:10.1038/nature10762 · Cited by 3,162
Self-citationDistant metastasis occurs late during the genetic evolution of pancreatic cancer
Yachida, S., Jones, S., Bozic, I., Antal, T., Leary, R., Fu, B., Kamiyama, M., Hruban, R. H., Eshleman, J. R., Nowak, M. A., et al. (2010) · Nature · doi:10.1038/nature09515 · Cited by 2,502
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
Ding, L., Ley, T. J., Larson, D. E., Miller, C. A., Koboldt, D. C., Welch, J. S., Ritchey, J. K., Young, M. A., Lamprecht, T., McLellan, M. D., et al. (2012) · Nature · doi:10.1038/nature10738 · Cited by 1,993
The origin and evolution of mutations in acute myeloid leukemia
Welch, J. S., Ley, T. J., Link, D. C., Miller, C. A., Larson, D. E., Koboldt, D. C., Wartman, L. D., Lamprecht, T. L., Liu, F., Xia, J., et al. (2012) · Cell · doi:10.1016/j.cell.2012.06.023 · Cited by 1,575
Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia
Jan, M., Snyder, T. M., Corces-Zimmerman, M. R., Vyas, P., Weissman, I. L., Quake, S. R., & Majeti, R. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3004315 · Cited by 721
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Cited by
Clonal haematopoiesis and dysregulation of the immune system
Belizaire, R., Wong, W. J., Robinette, M. L., & Ebert, B. L. (2023) · Nature Reviews Immunology · doi:10.1038/s41577-023-00843-3 · Cited by 161
Metadata
- Authors
- Paguirigan, A. L., Smith, J., Meshinchi, S., Carroll, M., Maley, C., & Radich, J. P.
- Affiliations
- Fred Hutchinson Cancer Research Center, Seattle, WA 98117, USA.
- University of Pennsylvania, Philadelphia, PA, 19104, USA.
- Center for Evolution and Cancer, Helen Diller Family Comprehensive Cancer Center and Department of Surgery, University of California, San Francisco, San Francisco, CA 94158, USA.
- Venue
- Science Translational Medicine
- Published
- 2015-04
- Volume
- 7
- Issue
- 281
- ISSN
- 1946-6234
- 1946-6242
- PMC
- PMC4405099
- Cited by
- 139
- References
- 6
- Language
- en
- Funders
- NIH (P01 CA91955, R01 CA149566, R01 CA114563, R01 CA140657)
- American Cancer Society (#117209-RSG-09-163-01-CNE, #117749-PF-09-288-01-CCE)
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- CoChat. (2026). Citation check: Single-cell genotyping demonstrates complex clonal diversity in acute myeloid leukemia. https://app.cochat.ai/papers/10.1126/scitranslmed.aaa0763
- The paper
- Paguirigan, A. L., Smith, J., Meshinchi, S., Carroll, M., Maley, C., & Radich, J. P. (2015). Single-cell genotyping demonstrates complex clonal diversity in acute myeloid leukemia. Science Translational Medicine. https://doi.org/10.1126/scitranslmed.aaa0763
