The DOI matches its Crossref record; 58 of the 59 references it cites were found in a registry or an index.
Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo
Open accessAbstract
Monoclonal antibodies that inhibit human T reg function in vivo may be used therapeutically in cancer or infections.
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1 retracted
Regulatory T Cells in the Human Immune System
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RetractedSingle-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
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Nivolumab plus Ipilimumab in Advanced Melanoma
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FOXP3+ regulatory T cells in the human immune system
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Research works printed but not linked: 1
- 10.1016/0003-2697(87)90021-2 · DOI
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Targeting TGF-β signal transduction for fibrosis and cancer therapy
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TGFβ biology in cancer progression and immunotherapy
Derynck, R., Turley, S. J., & Akhurst, R. J. (2021) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-020-0403-1 · Cited by 944
TGF-β1 – A truly transforming growth factor in fibrosis and immunity
Lodyga, M., & Hinz, B. (2019) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2019.12.010 · Cited by 467
Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins
Robertson, I. B., & Rifkin, D. B. (2016) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a021907 · Cited by 403
Metadata
- Authors
- Cuende, J., Liénart, S., Dedobbeleer, O., van der Woning, B., De Boeck, G., Stockis, J., Huygens, C., Colau, D., Somja, J., Delvenne, P., Hannon, M., Baron, F., Dumoutier, L., Renauld, J.-C., De Haard, H., Saunders, M., Coulie, P. G., & Lucas, S.
- Affiliations
- de Duve Institute (BE)
- arGEN-X BVBA, Technologiepark 30, B9052 Zwijnaarde, Gent, Belgium.
- Ludwig Cancer Research (BE)
- University of Liège (BE)
- Argenx (Belgium) (BE)
- Corresponding author
- Cuende, Julia
- Liénart, Stéphanie
- Lucas, Sophie
- ORCID
- Venue
- Science Translational Medicine
- Published
- 2015-04-22
- Volume
- 7
- Issue
- 284
- Pages
- 284ra56-284ra56
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- OpenAlex
- W2113024959
- Cited by
- 155
- References
- 59
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 17 · 2023: 13 · 2022: 16 · 2021: 20 · 2020: 17 · 2019: 15 · 2018: 14 · 2017: 12 · 2016: 12 · 2015: 5
- FWCI
- 7.04
- Type
- journal article
- Language
- en
- Open access
- green
- orbi.uliege.be
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B)) (submittedVersion)
- ORBi (University of Liège) (submittedVersion, other-oa)
- Funders
- Fondation contre le Cancer (Belgium)
- Fonds J. Maisin (Belgium)
- Fonds National pour la Recherche Scientifique
- Belgian Cancer Plan (Action 29_024)
- Fonds National pour la Recherche Scientifique (Belgium)
- Fondation Salus Sanguinis (Belgium)
- Actions de Recherche Concertees (ARC 09/14-021)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › TGF-β signaling in diseases
- Health Sciences › Medicine › Oncology › Cancer Immunotherapy and Biomarkers
- Keywords
- regulatory T cells, GARP, TGF-β1, monoclonal antibodies, TGF-β1 activation, immunosuppression, graft-versus-host disease, cancer immunotherapy, conformational epitopes, cancer vaccines, CTLA-4, PD-1/PD-L1
- MeSH terms
- Animals, Antibodies, Monoclonal, Epitopes, Graft vs Host Disease, Humans, Immunosuppressive Agents, Membrane Proteins, Methylation, Mice, Inbred BALB C, Mice, Transgenic, Protein Binding, Protein Conformation, Autoimmunity, Mice, SCID, Mice, Inbred NOD, T-Lymphocytes, Regulatory, Mice, Transforming Growth Factor beta1
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