Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy
Leverson, Joel D., Phillips, Darren C., Mitten, Michael J., Boghaert, Erwin R., Diaz, Dolores, Tahir, Stephen K., Belmont, Lisa D., Nimmer, Paul, Xiao, Yu, Ma, Xiaoju Max, Lowes, Kym N., Kovar, Peter, Chen, Jun, Jin, Sha, Smith, Morey, Xue, John, Zhang, Haichao, Oleksijew, Anatol, Magoc, Terrance J., Vaidya, Kedar S., Albert, Daniel H., Tarrant, Jacqueline M., La, Nghi, Wang, Le, Tao, Zhi-Fu, Wendt, Michael D., Sampath, Deepak, Rosenberg, Saul H., Tse, Chris, S. Huang, David C., Fairbrother, Wayne J., Elmore, Steven W., Souers, Andrew J.·2015·Science Translational Medicine
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- Overexposure to venetoclax is associated with prolonged-duration of neutropenia during venetoclax and azacitidine therapy in Japanese patients with acute myeloid leukemiaTakahiro Kobayashi, Honami Sato, Masatomo Miura, Yayoi Fukushi, Wataru Kuroki, Fumiko Ito, Kazuaki Teshima, Atsushi Watanabe, Naohito Fujishima, Isuzu Kobayashi et al. · 2024 · Cancer Chemotherapy and Pharmacology
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- BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced ApoptosisPrashanta Kumar Panda, Ana Carolina Paschoalini Mafra, Alliny C.S. Bastos, Li Cao, Maria Serra Bonet, Caitlyn B. Brashears, Ethan Yang Chen, Heather M. Benedict-Hamilton, William R. Ehrhardt, John S. Bomalaski et al. · 2025 · Clinical Cancer Research
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- The Role of ΔFosB on the Pro-survival Effect of PTHrP in Goat Mammary Epithelial CellsHui Li, Xiaotong Yao, Lihui Li, Huiling Zheng · 2016 · Applied Biochemistry and Biotechnology
- Advances in synthetic lethality modalities for glioblastoma multiformeSeidu A. Richard · 2024 · Open Medicine
- Exposure-response relationships of venetoclax in combination with carfilzomib and dexamethasone in relapsed/refractory t(11;14) multiple myeloma patientsMohamed Ali Badawi, Benjamin Engelhardt, Edyta Dobkowska, Rong Deng, Jonathan L. Kaufman, Rajeev M Menon, Ahmed Hamed Salem · 2024 · Investigational New Drugs
- A “Prozone-Like” Effect Influences the Efficacy of the Monoclonal Antibody ABT-700 against the Hepatocyte Growth Factor ReceptorKedar S. Vaidya, Anatol Oleksijew, Lora A. Tucker, William N. Pappano, Mark G. Anderson, Christine M. Grinnell, Qian Yun Zhang, Sarah J. Heighton, Michael J. Mitten, Sasmita Mishra et al. · 2017 · Pharmacology
- Pharmacological modulation of cell death in organ transplantationPietro E. Cippà, Thomas Hans Fehr · 2017 · Transplant International
- Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimeticsAnna L. Koessinger, Dominik Koessinger, Kevin Kinch, Laura Martínez‐Escardó, Nikki R. Paul, Yassmin Elmasry, Gaurav Malviya, Catherine Cloix, Kirsteen J. Campbell, Florian J. Bock et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Senolytic elimination of therapy-induced senescent cells by ABT-263 improves chemotherapeutic efficacy in esophageal squamous cell carcinomaDan Zhang, Ju Zhu, Rui Zou, Han Zhang, Bao-Ping Yu, Pan Li, Yang Luo, Zheng Jiang, Yu Hou, Jian-Wei Zhang · 2025 · Biochemical Pharmacology
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- Selecting efficacious Bcl-2 family inhibitors for optimal clinical outcome.Irfana Muqbil, Ramzi M. Mohammad · 2015 · Europe PMC (PubMed Central)
- Embryonic develop-associated gene 1 is overexpressed and acts as a tumor promoter in thyroid carcinomaJinkai Xu, Zongyu Li, Qinghua Su, Jun Zhao, Jiancang Ma · 2016 · Biomedicine & Pharmacotherapy
- Venetoclax: A novel B-cell lymphoma-2 inhibitor for chronic lymphocytic leukemia and other hematologic malignanciesJacqueline L. Olin, Carrie L. Griffiths, Morgan B. Smith · 2017 · Journal of Oncology Pharmacy Practice
- The Pt(S-pr-thiosal)2 and BCL1 Leukemia Lymphoma: Antitumor Activity In Vitro and In VivoŽana Besser Silconi, Vesna Rosic, Sasa Benazic, Gordana D. Radosavljevic, Marina Ž. Mijajlović, Jelena M. Pantic, Zoran Ratković, Gordana P. Radić, Aleksandar Arsenijević, Marija Milovanović et al. · 2022 · International Journal of Molecular Sciences
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- The Use of Genetically Modified Animals in Discovery ToxicologyDolores Diaz, Jonathan M. Maher · 2016
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