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Circulating mutant DNA to assess tumor dynamics

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Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer

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The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

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The value proposition of integrative diagnostics for (early) detection of cancer. On behalf of the EFLM interdisciplinary Task and Finish Group “CNAPS/CTC for early detection of cancer”

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Circulating tumor DNA for diagnosis, prognosis and treatment of gastrointestinal malignancies

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Diagnostic Utility of Next-Generation Sequencing in Circulating Free DNA and a Comparison With Matched Tissue in Gallbladder Carcinoma

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Circulating tumor DNA analysis predicts recurrence and avoids unnecessary adjuvant chemotherapy in I–IV colorectal cancer

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Exploring the clinical utility of liquid biopsy with cfDNA in cancer: A systematic review

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Clinical utility of emerging liquid biomarkers in advanced prostate cancer

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A prospective feasibility study evaluating the role of multimodality imaging and liquid biopsy for response assessment in locally advanced rectal carcinoma

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Co‐mutational assessment of circulating tumour DNA (ctDNA) during osimertinib treatment for T790M mutant lung cancer

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Association between Microsatellite Instability Status and Peri-Operative Release of Circulating Tumour Cells in Colorectal Cancer

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Future Perspectives in Detecting EGFR and ALK Gene Alterations in Liquid Biopsies of Patients with NSCLC

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Detection of Tumor Recurrence via Circulating Tumor DNA Profiling in Patients with Localized Lung Cancer: Clinical Considerations and Challenges

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Precision Medicine for Colorectal Cancer with Liquid Biopsy and Immunotherapy

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Translation of IDEA trial results into clinical practice: Analysis of the implementation of a new guideline for colon cancer

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Circulation tumour DNA in predicting recurrence and prognosis in operable colorectal cancer patients: A meta‐analysis

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Liquid Biopsy Analysis as a Tool for TKI-Based Treatment in Non-Small Cell Lung Cancer

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Circulating DNA in patients undergoing loco-regional treatment of colorectal cancer metastases: a systematic review and meta-analysis

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Recurrence Prediction by Circulating Tumor DNA in the Patient with Colorectal Liver Metastases After Hepatectomy: A Prospective Biomarker Study

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Redefining Colorectal Cancer by Tumor Biology

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Circulating Tumor DNA for Prediction of Complete Pathological Response to Neoadjuvant Radiochemotherapy in Locally Advanced Rectal Cancer (NEORECT Trial)

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Circulating tumor DNA as a biomarker for progression and survival in esophageal cancer after neoadjuvant therapy and esophagectomy: a systematic review and meta-analysis

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Decoding Glioblastoma Through Liquid Biopsy: Molecular Insights and Clinical Prospects

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Biomarkers in the development of individualized treatment regimens for colorectal cancer

Crutcher, M. M., & Waldman, S. A. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.1062423 · Cited by 14

Early Plasma Circulating Tumor DNA as a Potential Biomarker of Disease Recurrence in Non-metastatic Prostate Cancer

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Overview of the role of liquid biopsy in cancer management

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Monitoring of gastrointestinal carcinoma via molecular residual disease with circulating tumor DNA using a tumor‐informed assay

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A Practical Approach to Interpreting Circulating Tumor DNA in the Management of Gastrointestinal Cancers

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Tumor-Informed Circulating Tumor DNA for Minimal Residual Disease Detection in the Management of Colorectal Cancer

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Neoadjuvant chemoradiotherapy versus neoadjuvant chemotherapy for initially unresectable locally advanced colon cancer: short-term outcomes of an open-label, single-centre, randomised, controlled, phase 3 trial

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Liquid biopsy entering clinical practice: Past discoveries, current insights, and future innovations

Song, J., Xiong, Y., & Xiao, H. F. (2025) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2025.104613 · Cited by 16

The cornerstone of integrating circulating tumor DNA into cancer management

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Evolving Clinical Utility of Liquid Biopsy in Gastrointestinal Cancers

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Circulating tumor cells: what we know, what do we want to know about them and are they ready to be used in clinics?

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Personalized Treatment Selection and Disease Monitoring Using Circulating Tumor DNA Profiling in Real-World Cancer Patient Management

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Circulating Extracellular Vesicles in Gynecological Tumors: Realities and Challenges

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Genomic and epigenomic biomarkers in colorectal cancer: From diagnosis to therapy

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Comprehensive literature review of randomized clinical trials examining novel treatment advances in patients with colon cancer

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Circulating tumor DNA as a biomarker to guide therapy in post-operative locally advanced rectal cancer: the best option?

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Beyond traditional biopsies: the emerging role of ctDNA and MRD on breast cancer diagnosis and treatment

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Integrating Circulating Tumor DNA into Clinical Management of Colorectal Cancer: Practical Implications and Therapeutic Challenges

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Liquid biopsy – a narrative review with an update on current US governmental clinical trials targeting immunotherapy

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Circulating Tumor DNA: The Dawn of a New Era in the Optimization of Chemotherapeutic Strategies for Metastatic Colo-Rectal Cancer Focusing on RAS Mutation

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Postoperative circulating tumor DNA testing based on tumor naïve strategy after liver metastasis surgery in colorectal cancer patients

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Utility of ctDNA in predicting relapse in solid tumors after curative therapy: a meta-analysis

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Metachronous colorectal cancer metastasis: Who, what, when and what to do about it

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Molecular residual disease detection in resected, muscle-invasive urothelial cancer with a tissue-based comprehensive genomic profiling–informed personalized monitoring assay

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Molecular Biomarkers for Predicting Cancer Patient Radiosensitivity and Radiotoxicity in Clinical Practice

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Liquid biopsy for monitoring minimal residual disease in localized and locally-advanced non-small cell lung cancer after radical-intent treatment

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The Correlation between Plasma Circulating Tumor DNA and Radiographic Tumor Burden

Alexander, E. M., Miller, H. A., Egger, M. E., Smith, M. L., Yaddanapudi, K., & Linder, M. W. (2024) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2024.07.001 · Cited by 14

Circulating Tumor DNA as a Marker of Recurrence Risk in Stage III Colorectal Cancer: The α‐CORRECT Study

Diergaarde, B. B., Young, G., Hall, D. W., Mazloom, A. R., Costa, G. L., Subramaniam, S., Palomares, M. R., Garces, J., Baehner, F. L., Schoen, R. E., et al. (2025) · Journal of Surgical Oncology · doi:10.1002/jso.27989 · Cited by 15

Liquid biopsy: another tool towards tailored therapy in colorectal cancer

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Circulating cell-free DNA does not harbour a diagnostic benefit in cats with feline diffuse iris melanomas

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A fatal affair: Circulating tumor cell relationships that shape metastasis

Ozimski, L. L., Gremmelspacher, D., & Aceto, N. (2021) · iScience · doi:10.1016/j.isci.2021.103073 · Cited by 13

Liquid profiling of circulating tumor DNA in colorectal cancer: steps needed to achieve its full clinical value as standard care

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Exploring the Evolving Scope of Neoadjuvant Immunotherapy in NSCLC

Roller, J., Veeramachaneni, N. K., & Zhang, J. (2022) · Cancers · doi:10.3390/cancers14030741 · Cited by 14

Clinical Utility of Liquid Biopsy (Cell-free DNA) Based EGFR Mutation Detection Post treatment Initiation as a Disease Monitoring Tool in Patients With Advanced EGFR-mutant NSCLC

Behel, V., Chougule, A., Noronha, V., Patil, V. M., Menon, N. S., Singh, A. K., Chopade, S. R., Kumar, R., Shah, S., More, S. B., et al. (2022) · Clinical Lung Cancer · doi:10.1016/j.cllc.2022.04.002 · Cited by 13

Biomarker Development Using Liquid Biopsy in Hepatocellular Carcinoma

Grinspan, L. T., & Villanueva, A. (2022) · Seminars in Liver Disease · doi:10.1055/s-0042-1748924 · Cited by 13

Bioplatforms in liquid biopsy: advances in the techniques for isolation, characterization and clinical applications

Shah, U. J., Alsulimani, A., Ahmad, F., Mathkor, D. M., Alsaieedi, A., Harakeh, S., Nasiruddin, M., & Haque, S. (2022) · Biotechnology and Genetic Engineering Reviews · doi:10.1080/02648725.2022.2108994 · Cited by 14

Case report: Patient specific combination of surgery and immunotherapy in advanced squamous cell carcinoma of the head and neck – a case series and review of literature

Olmos, M., Lutz, R., Büntemeyer, T.-O., Glajzer, J., Nobis, C., Ries, J., Möst, T., Eckstein, M., Hecht, M., Gostian, A., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.970823 · Cited by 13

T-cell leukemia/lymphoma-1A predicts the clinical outcome for patients with stage II/III colorectal cancer

Li, H., Yan, X., Liu, L., Huang, L., Yin, M., Pan, C., Zhang, P., & Qin, H. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.01.128 · Cited by 13

The utilization of next-generation sequencing to detect somatic mutations and predict clinical prognosis of Chinese non-small cell lung cancer patients

Cao, L., Long, L., Li, M., Yang, H., Deng, P., Mao, X., Xiang, J., Li, B., Zhang, T., & He, J. (2018) · OncoTargets and Therapy · doi:10.2147/ott.s155995 · Cited by 13

Incorporating liquid biopsies into treatment decision-making: obstacles and possibilities

Beije, N., Martens, J. W. M., & Sleijfer, S. (2019) · Drug Discovery Today · doi:10.1016/j.drudis.2019.05.028 · Cited by 13

Liquid biopsy, a paradigm shift in oncology: what interventional radiologists should know

Calandri, M., Siravegna, G., Yevich, S. M., Stranieri, G., Gazzera, C., Kopetz, S., Fonio, P., Gupta, S. K., Bardelli, A., Veltri, A., et al. (2020) · European Radiology · doi:10.1007/s00330-020-06700-4 · Cited by 13

Culture and application of conditionally reprogrammed primary tumor cells

Zhong, M., & Fu, L. (2020) · Gastroenterology report · doi:10.1093/gastro/goaa023 · Cited by 13

A Pilot Study Analyzing the Clinical Utility of Comprehensive Genomic Profiling Using Plasma Cell-Free DNA for Solid Tumor Patients in Japan (PROFILE Study)

Matsudera, S., Kano, Y., Aoyagi, Y., Tohyama, K., Takahashi, K., Kumaki, Y., Mitsumura, T., Kimura, K., Onishi, I., Takemoto, A., et al. (2021) · Annals of Surgical Oncology · doi:10.1245/s10434-021-09856-5 · Cited by 13

ctDNA to Guide Treatment of Colorectal Cancer: Ready for Standard of Care?

Puccini, A., Martelli, V., Pastorino, A., Sciallero, S., & Sobrero, A. F. (2023) · Current Treatment Options in Oncology · doi:10.1007/s11864-022-01048-x · Cited by 13

Genetic landscape of breast cancer and mutation tracking with circulating tumor DNA in Chinese women

Wang, Y., Lin, L., Li, L., Wen, J., Chi, Y., Hao, R., Dai, X., Chen, Y., Huang, D.-P., Zhou, Y., et al. (2021) · Aging · doi:10.18632/aging.202888 · Cited by 12

FDA-led consortium studies advance quality control of targeted next generation sequencing assays for precision oncology

Li, D., Kusko, R. L., Ning, B., Tong, W., Johann, D. J., & Xu, J. (2021) · Precision Cancer Medicine · doi:10.21037/pcm-21-29 · Cited by 12

A longitudinal cohort study of watch and wait in complete clinical responders after chemo-radiotherapy for localised rectal cancer: study protocol

Vatandoust, S., Wattchow, D. A., Sposato, L., Michael, M., Leung, J., Gormly, K. L., Chen, G., Symonds, E. L., Tie, J., Papanicolas, L. E., et al. (2022) · BMC Cancer · doi:10.1186/s12885-022-09304-x · Cited by 12

Circulating tumour DNA monitoring and early treatment for relapse: views from patients with early-stage melanoma

Woof, V. G., Lee, R. J., Lorigan, P. C., & French, D. (2022) · British Journal of Cancer · doi:10.1038/s41416-022-01766-x · Cited by 15

Circulating tumor DNA dynamics and response to immunotherapy in colorectal cancer

Gong, J., Aguirre, F. P., Hazelett, D. J., Alvarez, R., Zhou, L., Hendifar, A. E., Osipov, A., Zaghiyan, K. N., Cho, M. T., Gangi, A., et al. (2022) · Molecular and Clinical Oncology · doi:10.3892/mco.2022.2533 · Cited by 13

Targeted Mutational Analysis of Circulating Tumor DNA to Decipher Temporal Heterogeneity of High-Grade Serous Ovarian Cancer

Paracchini, L., Mannarino, L., Beltrame, L., Landoni, F., Fruscio, R., Grassi, T., Dalessandro, M. L., D’Incalci, M., & Marchini, S. (2022) · Cancers · doi:10.3390/cancers14153697 · Cited by 12

Circulating tumor DNA predicts recurrence and assesses prognosis in operable gastric cancer: A systematic review and meta-analysis

Mi, J., Wang, R., Han, X., Ma, R.-J., & Li, H. (2023) · Medicine · doi:10.1097/md.0000000000036228 · Cited by 12

Incidental pathogenic germline alterations detected through liquid biopsy in patients with solid tumors: prevalence, clinical utility and implications

Laguna, J. C., Pastor, B., Nalda, I., Hijazo‐Pechero, S., Teixidó, C., Potrony, M., Puig‐Butillé, J. A., & Mezquita, L. (2024) · British Journal of Cancer · doi:10.1038/s41416-024-02607-9 · Cited by 13

Clinical impact of circulating tumor DNA to track minimal residual disease in colorectal cancer patients. Hopes and limitations

Soueidy, C., Zaanan, A., Gelli, M., Moati, É., Gallois, C., Taly, V., Laurent‐Puig, P., Benhaïm, L., & Taı̈eb, J. (2024) · ESMO Gastrointestinal Oncology · doi:10.1016/j.esmogo.2024.100068 · Cited by 15

Quantification method of ctDNA using cell-free DNA methylation profile for noninvasive screening and monitoring of colon cancer

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A standing platform for cancer drug development using ctDNA-based evidence of recurrence

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