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Intraoperative Tissue Identification Using Rapid Evaporative Ionization Mass Spectrometry

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Sequential Detection of Lipids, Metabolites, and Proteins in One Tissue for Improved Cancer Differentiation Accuracy

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Paper Spray Ionization Mass Spectrometry as a Potential Tool for Early Diagnosis of Cervical Cancer

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Metabolic profiles of human brain parenchyma and glioma for rapid tissue diagnosis by targeted desorption electrospray ionization mass spectrometry

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Rapid determination of isocitrate dehydrogenase mutation status of human gliomas by extraction nanoelectrospray using a miniature mass spectrometer

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Pocket-Size “MasSpec Pointer” for Ambient Ionization Mass Spectrometry

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Untangling the Metabolic Reprogramming in Brain Cancer: Discovering Key Molecular Players Using Mass Spectrometry

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Inline cartridge extraction for rapid brain tumor tissue identification by molecular profiling

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Recent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and Metabolomics

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Stable Isotope Tracing Analysis in Cancer Research: Advancements and Challenges in Identifying Dysregulated Cancer Metabolism and Treatment Strategies

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Ambient mass spectrometry for the molecular diagnosis of lung cancer

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Hepatocarcinoma Discrimination by Ratiometric Lipid Profiles Using Tip-Contact Sampling/Ionization Mass Spectrometry

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Intraoperative Identification of Thyroid and Parathyroid Tissues During Human Endocrine Surgery Using the MasSpec Pen

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Intraoperative Evaluation of Breast Tissues During Breast Cancer Operations Using the MasSpec Pen

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Lipidomic analysis and diagnosis of glioblastoma multiforme with rapid evaporative ionization mass spectrometry

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Perspective: Advancing Understanding of Population Nutrient–Health Relations via Metabolomics and Precision Phenotypes

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Ambient desorption/ionization mass spectrometry for direct solid material analysis

Amatya, S., & Cha, S. (2021) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2021.116420 · Cited by 19

Optical molecular imaging technology and its application in precise surgical navigation of liver cancer

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Unified representation of high- and low-resolution spectra to facilitate application of mass spectrometric techniques in clinical practice

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Non-invasive Biodiversified Sensors: A Modernized Screening Technology for Cancer

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Lipid Profiling in Cancer Diagnosis with Hand-Held Ambient Mass Spectrometry Probes: Addressing the Late-Stage Performance Concerns

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Review of Recent Advances in Lipid Analysis of Biological Samples via Ambient Ionization Mass Spectrometry

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Coupling handheld liquid microjunction-surface sampling probe (hLMJ-SSP) to the miniature mass spectrometer for automated and in-situ surface analysis

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Capillary-in-Capillary Electrospray Ionization (CC-ESI) Source Enabling Convenient Sampling and Quantitative Analysis for Point-of-Care Testing

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Advancements in Intraoperative Near-Infrared Fluorescence Imaging for Accurate Tumor Resection: A Promising Technique for Improved Surgical Outcomes and Patient Survival

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PiTMaP: A New Analytical Platform for High-Throughput Direct Metabolome Analysis by Probe Electrospray Ionization/Tandem Mass Spectrometry Using an R Software-Based Data Pipeline

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Roles of Lipid Profiles in Human Non-Small Cell Lung Cancer

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Maciel, L. Í. L., Pereira, I., Ramalho, R. R. F., Ribeiro, R. I., Pinto, M. C. X., & Vaz, B. G. (2021) · International Journal of Mass Spectrometry · doi:10.1016/j.ijms.2021.116730 · Cited by 17

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Mass Spectrometry Analysis for Clinical Applications: A Review

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Haapala, I., Karjalainen, M., Kontunen, A., Vehkaoja, A. T., Nordfors, K., Haapasalo, H. K., Haapasalo, J. A., Oksala, N., & Roine, A. (2019) · Journal of neurosurgery · doi:10.3171/2019.3.jns19274 · Cited by 17

Lipidomic Profiling of Colorectal Lesions for Real-Time Tissue Recognition and Risk-Stratification Using Rapid Evaporative Ionization Mass Spectrometry

Mason, S., Manoli, E., Alexander, J. L., Poynter, L., Ford, L., Paizs, P., Adebesin, A., McKenzie, J. S., Rosini, F., Goldin, R. D., et al. (2021) · Annals of Surgery · doi:10.1097/sla.0000000000005164 · Cited by 17

Picosecond Infrared Laser Mass Spectrometry Identifies a Metabolite Array for 10 s Diagnosis of Select Skin Cancer Types: A Proof-of-Concept Feasibility Study

Katz, L., Woolman, M., Kiyota, T., Pires, L., Zaidi, M., Hofer, S. O. P., Leong, W. L., Wouters, B. G., Ghazarian, D., Chan, A., et al. (2022) · Analytical Chemistry · doi:10.1021/acs.analchem.2c03918 · Cited by 16

Modern machine‐learning applications in ambient ionization mass spectrometry

Sorokin, A., Игоревич, П. С., Zavorotnyuk, D. S., Shamraeva, M. A., Bormotov, D. S., & Popov, I. A. (2024) · Mass Spectrometry Reviews · doi:10.1002/mas.21886 · Cited by 16

Direct ion generation from swabs

Jarmusch, A. K., Pirro, V., Logsdon, D. L., & Cooks, R. G. (2018) · Talanta · doi:10.1016/j.talanta.2018.02.105 · Cited by 16

An Update on Surgical Margins in the Head Neck Squamous Cell Carcinoma: Assessment, Clinical Outcome, and Future Directions

Singh, A. G., Qayyumi, B. N., & Chaturvedi, P. (2020) · Current Oncology Reports · doi:10.1007/s11912-020-00942-7 · Cited by 16

Real-time lipid patterns to classify viable and necrotic liver tumors

Vaysse, P., Grabsch, H. I., van den Hout, M. F. C. M., Bemelmans, M. H. A., Heeren, R. M. A., Damink, S. W. M. O., & Siegel, T. P. (2021) · Laboratory Investigation · doi:10.1038/s41374-020-00526-w · Cited by 16

Direct quantitative profiling of amino acids in tissues for the assessment of lung cancer

Lu, H., Li, Y., Zhang, H., Chingin, K., Wei, Y., Huang, K., & Feng, S. (2021) · Talanta · doi:10.1016/j.talanta.2021.122544 · Cited by 16

Metabolomic Phenotyping of Gliomas: What Can We Get with Simplified Protocol for Intact Tissue Analysis?

Goryńska, P. Z., Chmara, K., Kupcewicz, B., Goryński, K., Jaroch, K., Pa̧czkowski, D., Furtak, J., Harat, M., & Bojko, B. (2022) · Cancers · doi:10.3390/cancers14020312 · Cited by 16

Advances and Emerging Medical Applications of Direct Mass Spectrometry Technologies for Tissue Analysis

King, M. E., Lin, M., Spradlin, M., & Eberlin, L. S. (2023) · Annual Review of Analytical Chemistry · doi:10.1146/annurev-anchem-061020-015544 · Cited by 16

Imaging with mass spectrometry: Which ionization technique is best?

Prentice, B. M. (2024) · Journal of Mass Spectrometry · doi:10.1002/jms.5016 · Cited by 16

An overview of biological applications and fundamentals of new inlet and vacuum ionization technologies

Trimpin, S., Marshall, D. D., Karki, S., Madarshahian, S., Hoang, K., Meher, A. K., Pophristic, M., Richards, A., Lietz, C. B., Fischer, J. L., et al. (2020) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.8829 · Cited by 16

In-capillary aptamer-functionalized dispersive solid-phase microextraction for dynamic transfer enrichment and miniature mass spectrometry analysis: A magnetically driven capture-and-release strategy

Li, L., Zhang, Y., Zhao, L., Lv, Y., Qu, F., & Ma, Q. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.149997 · Cited by 15

Dual Laser and Desorption Electrospray Ionization Mass Spectrometry Imaging Using the Same Interface

Katz, L., Woolman, M., Talbot, F. O., Amara-Belgadi, S., Wu, M., Tortorella, S., Das, S., Ginsberg, H. J., & Zarrine‐Afsar, A. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.9b05340 · Cited by 15

In Vivo Chemical Analysis of Plant Sap from the Xylem and Single Parenchymal Cells by Capillary Microsampling Electrospray Ionization Mass Spectrometry

Samarah, L. Z., Tran, T. H., Stacey, G. S., & Vértes, Á. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.0c00939 · Cited by 15

Electrochemical tracing of hypoxia glycolysis by carbon nanotube sensors, a new hallmark for intraoperative detection of suspicious margins to breast neoplasia

Miripour, Z. S., Abbasvandi, F., Aghaee, P., Najafikhoshnoo, S., Faramarzpour, M., Mohaghegh, P., Hoseinpour, P., Namdar, N., Amiri, M. H., Ghafari, H., et al. (2021) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10236 · Cited by 15

Droplet-based extraction mass spectrometry

Zhang, X., Na, N., & Ouyang, J. (2021) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2021.116366 · Cited by 15

Mass spectrometry for metabolomics analysis: Applications in neonatal and cancer screening

Grooms, A. J., Burris, B. J., & Badu-Tawiah, A. K. (2022) · Mass Spectrometry Reviews · doi:10.1002/mas.21826 · Cited by 15

Machine learning-empowered cis -diol metabolic fingerprinting enables precise diagnosis of primary liver cancer

Li, P., Xu, S., Han, Y., He, H., & Liu, Z. (2023) · Chemical Science · doi:10.1039/d2sc05541d · Cited by 15

Three-dimensional histological electrophoresis enables fast automatic distinguishment of cancer margins and lymph node metastases

Zhang, F., Xu, J., Yue, Y., Wang, Y., Sun, J., Song, D., Zhang, C., Qu, L., Zhu, S., Zhang, J., et al. (2023) · Science Advances · doi:10.1126/sciadv.adg2690 · Cited by 15

Development of a robotics platform for automated multi‐ionization mass spectrometry

Karki, S., Meher, A. K., Inutan, E. D., Pophristic, M., Marshall, D. D., Rackers, K. J., Trimpin, S., & McEwen, C. N. (2019) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.8449 · Cited by 15

Meat provenance - Advances and opportunities in rapid spectral techniques for authentication of dietary background and geographical origin of meat

Shaheen, S., Cama‐Moncunill, R., MOLONEY, A. P., Birse, N., Ferragina, A., Dunne, P. G., Grasso, S., Hamill, R. M., & Monahan, F. J. (2024) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2024.104557 · Cited by 14

Assessment of Metabolic Signature for Cancer Diagnosis Using Desorption Electrospray Ionization Mass Spectrometric Imaging

Banerjee, S., & Manna, S. K. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9027-6_15 · Cited by 14

A Review of International Biobanks and Networks: Success Factors and Key Benchmarks—A 10-Year Retrospective Review

Catchpoole, D. R., Devereux, L. M., Watson, P. H., Mes‐Masson, A., Luna-Crespo, F., Thomas, G. A., Pitman, H., Speirs, V., Hall, A. G., Bollinger, N., et al. (2019) · Biopreservation and Biobanking · doi:10.1089/bio.2019.29060.djc.si · Cited by 14

Individualized metabolomics: opportunities and challenges

Misra, B. B. (2019) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2019-0130 · Cited by 14

Application of Intraoperative Mass Spectrometry and Data Analytics for Oncological Margin Detection, A Review

Santilli, A., Ren, K. Y. M., Oleschuk, R. D., Kaufmann, M., Rudan, J. F., Gabor Fichtinger, A., & Mousavi, P. (2022) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2021.3139992 · Cited by 14

Detection of Protein and Metabolites in Cancer Analyses by MALDI 2000–2025

Bartusik‐Aebisher, D., Raj, D. R. J., & Aebisher, D. (2025) · Cancers · doi:10.3390/cancers17213524 · Cited by 13

Direct detection of the psychoactive substance MT‐45 in human tissue samples by probe electrospray ionization‐tandem mass spectrometry

Usui, K., Murata, T., Fujita, Y., Kamijo, Y., Hanazawa, T., Yoshizawa, T., & Funayama, M. (2018) · Drug Testing and Analysis · doi:10.1002/dta.2390 · Cited by 13

Spatial Omics Imaging of Fresh-Frozen Tissue and Routine FFPE Histopathology of a Single Cancer Needle Core Biopsy: A Freezing Device and Multimodal Workflow

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