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Tibshirani, R. (1996) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1996.tb02080.x · Cited by 51,482

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Macario, A. (2010) · Journal of Clinical Anesthesia · doi:10.1016/j.jclinane.2010.02.003 · Cited by 658

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Otsuka, Y. (2020) · Journal of the Mass Spectrometry Society of Japan · doi:10.5702/massspec.20-106 · Cited by 3

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Song, X., & Chen, H. (2020) · Wiley eBooks · doi:10.1002/9780470027318.a9640 · Cited by 3

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AI-based prediction of androgen receptor expression and its prognostic significance in prostate cancer

Zhang, J., Ding, F., Guo, Y., Wei, X., Jing, J., Xu, F., Chen, H., Guo, Z., You, Z., Liang, B., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-88199-7 · Cited by 2

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Lin, L.-E., Chen, C.-L., Huang, Y.-C., Chung, H.-H., Lin, C.-W., Chen, K.-C., Peng, Y.-J., Ding, S.-T., Wang, M.-Y., Shen, T.-L., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/657494 · Cited by 2

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Abbasvandi, F., Miripour, Z. S., Bayat, M., Mousavi‐kiasary, S. M. S., Shayanfar, S., Shojaeian, F., Aghaei, F., Jahanbakhshi, F., Abbasvandi, N., Omrani-Hashemi, M., et al. (2024) · Diagnostic Pathology · doi:10.1186/s13000-024-01574-2 · Cited by 1

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Fox, S. A., & Farah, C. S. (2018) · Oral Diseases · doi:10.1111/odi.12897 · Cited by 1

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Ferreira, V. G., Feitor, J. F., Almeida, M. B., Cardoso, D. R., & Carrilho, E. (2021) · Springer eBooks · doi:10.1007/978-3-030-82381-8_1 · Cited by 1

Ex vivo study of molecular changes of stained teeth following hydrogen peroxide and peroxymonosulfate treatments

Gomes, P. W. P., Zuffa, S., Bauermeister, A., Caraballo‐Rodríguez, A. M., Zhao, H. N., Mannochio-Russo, H., Dogo‐Isonagie, C., Patel, O. P., Pimenta, P., Gronlund, J., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-43201-y · Cited by 2

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Tebani, A., & Bekri, S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815249-2.00005-1

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Huber, C. G., Pagel, K., Hoffmann, W., Heiles, S., Schäfer, K. C., Kompauer, M., Gerbig, S., & Soltwisch, J. (2018) · Nachrichten aus der Chemie · doi:10.1002/nadc.20184070741

Development of ‘Ready to Use Kits’ for the simultaneous qualification and quantification of drugs in different matrices using Mass Spectrometry, expanded with the application of multimodal imaging techniques

Genangeli (2019) · doi:10.26481/dis.20191203mg

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Looby, N. (2020) · UWSpace (University of Waterloo)

Use of Intraoperative Radioguidance in Recurrent Merkel Carcinoma

Beniey, M., Destrempes, N., Coulombe, G., Khoury, M. M. E., & Nassif, E. (2020) · Case Reports in Surgery · doi:10.1155/2020/1789185

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佐治, 泰., & 麻生, 実. (1963) · 日本建築学会論文報告集

References

(2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816081-7.09986-1

Introduction

Srivastava, R. (2019) · Springer eBooks · doi:10.1007/978-981-13-6748-9_1

Oncometabolites and their role in cancer

Gill, E. L., Patel, K., & Rakheja, D. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-824302-2.00003-5

Metabolomics: a systems approach in studying of cancer biology

Kulić, A., Penić-Grgaš, H., Skerlev, M., Plavetić, N. D., Pleština, S., Sedlić, F., Pašalić, D., & Zagreb Emergency Medicine Service, Z. (2019) · World Journal of Medical Oncology · doi:10.52338/wjoncgy.2022.1007

Clinical application of mass spectrometry imaging for analysis of bone and cartilage

Nauta, S. P. (2023) · doi:10.26481/dis.20230306sn

Current Methods for Intraoperative Application

Frattini, F., Mitsis, M. C., & Lianos, G. D. (2023) · Springer eBooks · doi:10.1007/978-3-031-33517-4_19

Current Methods for Intraoperative Application

Paraskevaidi, M. (2023) · Springer eBooks · doi:10.1007/978-3-031-33517-4_13

Ambient Ionisation Mass Spectrometry for Microbial Analysis

Strittmatter, N. (2023) · Royal Society of Chemistry eBooks · doi:10.1039/bk9781837670338-00076

High-throughput metabolome comparison of cutaneous squamous cell carcinoma, basal cell carcinoma, and healthy skin with e-biopsy samplingPreprint

Louie, L., Wise, J., Berl, A., Shir‐az, O., Kravtsov, V., Yakhini, Z., Shalom, A., Golberg, A., & Vitkin, E. I. (2024) · medRxiv · doi:10.1101/2024.03.06.24303646

Oncoproteomics by 3D MALDI with MRI-PET Imaging in Cancer

Sharma, R. D., Pathak, Y. V., Itharat, A., & Trivedi, A. (2024) · Springer eBooks · doi:10.1007/978-3-031-64021-6_17

Fundamentals of in vivo sampling

Woźniczka, K., Yu, M., Looby, N., & Roszkowska, A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15978-7.00091-6

Sampling and sample preparation for LC-MS-based metabolomics of samples of mammalian origin

Schoeny, H., & Koellensperger, G. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15978-7.00094-1

Strategies for the direct coupling of sampling and sample preparation to ambient mass spectrometry

Tascón, M. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-15978-7.00124-7

Evaluation of the Concordance of Cancer Diagnostic Probe Findings During Surgery and Suspected Distortion in Pre-surgical Mammography Based on Pathology

Delshad, B., Abdolahad, M., Aghasi, M., Hosseinpour, P., Kohan, F. Z., & Akbari, M. E. (2025) · Indian Journal of Surgical Oncology · doi:10.1007/s13193-025-02261-4

Lung Malignancies

Liebowitz, A., Posawatz, D., & Wiener, D. C. (2025) · Thoracic surgery clinics/Thorac. surg. clin. · doi:10.1016/j.thorsurg.2025.07.011

Mass spectrometry techniques for pharmaceutical analysis without sample pretreatment

Gong, X., Wang, J., Liu, S., & Chen, H. (2025) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/csb-2025-5197

Fundamentals of Mass Spectrometry

Orahoske, C. M., Lusk, H., Pickard, S. C., & Wu, A. H. B. (2025) · Springer eBooks · doi:10.1007/978-3-032-03852-4_2

Non-proximate, Hand-Held Probe with Positional Feedback for Real-Time Analysis of Three-Dimensional Object Surfaces

Newsome, G. A. (2026) · Journal of the American Society for Mass Spectrometry · doi:10.1021/jasms.5c00296

Application of Ambient Ionization Mass Spectrometry to the Analysis of Cannabis

Garosi, B., & Musah, R. A. (2026) · Annual Review of Analytical Chemistry · doi:10.1146/annurev-anchem-080524-100042

Surgical tissue profiling and computational pipeline using the liquid microjunction surface sampling probe (LMJ-SSP) mass spectrometry: a proof-of-concept study

Hermann, M., Thériault, R., Yu, J., Kaufmann, M., Ren, K. Y. M., Liu, C., LeBlanc, Y., Covey, T. R., Ellis, R. E., & Oleschuk, R. D. (2026) · Canadian Journal of Chemistry · doi:10.1139/cjc-2025-0279

Localized Accumulation of Tri‐n‐Propylamine Prolongs Electrochemiluminescence for Tumor Model Spheroid Analysis

Gupta, V., Hill, M. L., Nortz, S. P., Choudhary, Y., Rana, A., & Dick, J. E. (2026) · Angewandte Chemie · doi:10.1002/ange.8508105

Automated sample pretreatment technologies: from surface-based liquid microjunction sampling to flow-based platforms

Jiang, X., Ma, Q., & Feng, X. (2026) · Talanta · doi:10.1016/j.talanta.2026.130157

Toward Metabolomics Analyses With Combined Capillary Vibrating Sharp‐Edge Spray Ionization and Atmospheric Pressure Chemical Ionization

Pursell, M. E., Ojanuga, A., Banerjee, C., Ezeigbo, E., Rahman, M., Dewasurendra, V. K., Hughart, T. B., Johnson, M. B., Sultana, M. N., Guo, X., et al. (2026) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.70110

Advances in intraoperative margin assessment for solid tumors: Toward a new era of personalized precision surgery

Gao, Z., Zhao, L., Li, Z., Wang, R., Liu, X., Qi, X., Zhang, X., Liu, H., Yu, Y., Yu, B., et al. (2026) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2026.111976

The ELVIS Probe: Combining Laser Pointer Desorption, Venturi‐Assisted Plume Transport, and Electrospray Ionization in a Simple Handheld Tool for Remote Ambient Mass Spectrometry

Machado, A. F., Franco, M. F., Zacca, J. J., Correa, D. N., Paoli, M. D., Klitzke, C. F., & Eberlin, M. N. (2026) · Journal of Mass Spectrometry · doi:10.1002/jms.70085

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