Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms

Neutrophil Extracellular Traps Kill Bacteria

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Extracellular DNA traps promote thrombosis

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A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis

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Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

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Neutrophil extracellular traps promote deep vein thrombosis in mice

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Neutrophils at the Crossroads: Unraveling the Multifaceted Role in the Tumor Microenvironment

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Cardiovascular Disease Among Patients With AML and CHIP-Related Mutations

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NETs in APS: Current Knowledge and Future Perspectives

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Identification and characterization of a novel casein anticoagulant peptide derived from in vivo digestion

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Simvastatin Reduces NETosis to Attenuate Severe Asthma by Inhibiting PAD4 Expression

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Somatic Mutations in Cardiovascular Disease

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Spontaneous formation of neutrophil extracellular traps is associated with autophagy

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Neutrophil extracellular traps: New players in cancer research

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Diverse Neutrophil Functions in Cancer and Promising Neutrophil-Based Cancer Therapies

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The Role of Neutrophil Extracellular Traps in Central Nervous System Diseases and Prospects for Clinical Application

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Association of neutrophil extracellular traps with the production of circulating DNA in patients with colorectal cancer

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Clinical significance of neutrophil extracellular traps biomarkers in thrombosis

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Clonal haematopoiesis in cardiovascular disease: prognostic role and novel therapeutic target

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Givinostat: an emerging treatment for polycythemia vera

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The Role of Neutrophil Extracellular Traps in Cancer

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High circulating levels of MPO-DNA are associated with thrombosis in patients with MPN

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Dysregulated haemostasis in thrombo-inflammatory disease

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Mechanisms of cancer-associated thrombosis

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Platelet Dysfunction and Thrombosis in JAK2 V617F -Mutated Primary Myelofibrotic Mice

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Cancer and thrombosis: new insights to an old problem

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Neutrophil extracellular traps in tumor progression and immunotherapy

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Platelets and neutrophils cooperate to induce increased neutrophil extracellular trap formation in JAK2V617F myeloproliferative neoplasms

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The coming of age of neutrophil extracellular traps in thrombosis: Where are we now and where are we headed?

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Association between periodontitis and inflammatory comorbidities: The common role of innate immune cells, underlying mechanisms and therapeutic targets

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Clonal Hematopoiesis and Its Impact on Cardiovascular Disease

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Clonal hematopoiesis: Pre-cancer PLUS

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What To Tell Your Patient With Clonal Hematopoiesis And Why: Insights From Two Specialized Clinics

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Endothelial JAK2V617F mutation leads to thrombosis, vasculopathy, and cardiomyopathy in a murine model of myeloproliferative neoplasm

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Regulating Neutrophil PAD4/NOX-Dependent Cerebrovasular Thromboinflammation

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Mechanistic insights into the interplays between neutrophils and other immune cells in cancer development and progression

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The AI-Assisted Identification and Clinical Efficacy of Baricitinib in the Treatment of COVID-19

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Endothelial transferrin receptor 1 contributes to thrombogenesis through cascade ferroptosis

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The clonal hematopoiesis mutation Jak2 aggravates endothelial injury and thrombosis in arteries with erosion-like intimas

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Thrombosis in myeloproliferative neoplasms: a viewpoint on its impact on myelofibrosis, mortality, and solid tumors

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Neutrophil extracellular traps participate in the development of cancer-associated thrombosis in patients with gastric cancer

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Clonal Hematopoiesis of Indeterminate Potential From a Heart Failure Specialist's Point of View

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Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19

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The regulatory mechanism of neutrophil extracellular traps in cancer biological behavior

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The Microenvironment in Myeloproliferative Neoplasms

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Clonal hematopoiesis and cardiovascular disease: deciphering interconnections

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Is Hematopoietic Clonality of Indetermined Potential a Risk Factor for Pulmonary Embolism?

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Thromboinflammation in Myeloproliferative Neoplasms (MPN)—A Puzzle Still to Be Solved

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Neutrophil Extracellular Traps (NETs) as drivers of atherosclerosis: Pathogenic mechanisms and therapeutic opportunities

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Interplay between Clonal Hematopoiesis of Indeterminate Potential and Metabolism

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Among classic myeloproliferative neoplasms, essential thrombocythemia is associated with the greatest risk of venous thromboembolism during COVID-19

Barbui, T., Stefano, V. D., Álvarez‐Larrán, A., Iurlo, A., Masciulli, A., Carobbio, A., Ghirardi, A., Ferrari, A., Cancelli, V., Elli, E. M., et al. (2021) · Blood Cancer Journal · doi:10.1038/s41408-021-00417-3 · Cited by 36

NLRP3-Induced NETosis: A Potential Therapeutic Target for Ischemic Thrombotic Diseases?

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Polycythemia Vera-Associated Complications: Pathogenesis, Clinical Manifestations, And Effects On Outcomes

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Traps N' Clots: NET-Mediated Thrombosis and Related Diseases

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Microvascular Thrombosis as a Critical Factor in Severe COVID-19

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Macrophage DNases Limit Neutrophil Extracellular Trap–Mediated Defective Efferocytosis in Atherosclerosis

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Adenosine from a biologic source regulates neutrophil extracellular traps (NETs)

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Extracellular DNA Traps: Origin, Function and Implications for Anti-Cancer Therapies

Mamtimin, M., Pinarci, A., Han, C., Braun, A., Anders, H., Gudermann, T. W., & Mammadova‐Bach, E. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.869706 · Cited by 35

Updates in the management of polycythemia vera and essential thrombocythemia

Bose, P., & Verstovšek, S. (2019) · Therapeutic Advances in Hematology · doi:10.1177/2040620719870052 · Cited by 34

Genomic Aging, Clonal Hematopoiesis, and Cardiovascular Disease

Natarajan, P. (2022) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.122.318181 · Cited by 35

Clonal Hematopoiesis Confers Predisposition to Both Cardiovascular Disease and Cancer: A Newly Recognized Link Between Two Major Killers

Ebert, B. L., & Libby, P. (2018) · Annals of Internal Medicine · doi:10.7326/m18-0737 · Cited by 34

Mechanisms of platelet activation in cancer-associated thrombosis: a focus on myeloproliferative neoplasms

Bekendam, R. H., & Ravid, K. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1207395 · Cited by 33

Emerging Role of Neutrophils in the Thrombosis of Chronic Myeloproliferative Neoplasms

Ferrer‐Marín, F., Cuenca‐Zamora, E. J., Guijarro-Carrillo, P. J., & Teruel‐Montoya, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22031143 · Cited by 33

Cardiovascular Risk in Philadelphia-Negative Myeloproliferative Neoplasms: Mechanisms and Implications—A Narrative Review

Todor, S. B., Ichim, C., Boicean, A., & Mihăilă, R. G. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46080496 · Cited by 32

JAK2 allele burden is correlated with a risk of venous but not arterial thrombosis

Soudet, S., Roy, G. L., Cadet, E., Michaud, A., Morel, P., Marolleau, J. P., & Sevestre, M. (2022) · Thrombosis Research · doi:10.1016/j.thromres.2022.01.011 · Cited by 32

Addressing and proposing solutions for unmet clinical needs in the management of myeloproliferative neoplasm-associated thrombosis: A consensus-based position paper

Barbui, T., Stefano, V. D., Falanga, A., Finazzi, G., Martinelli, I., Rodeghiero, F., Vannucchi, A. M., & Barosi, G. (2019) · Blood Cancer Journal · doi:10.1038/s41408-019-0225-5 · Cited by 31

Novel Pathophysiological Mechanisms of Thrombosis in Myeloproliferative Neoplasms

Reeves, B., & Beckman, J. D. (2021) · Current Hematologic Malignancy Reports · doi:10.1007/s11899-021-00630-8 · Cited by 31

Clonal Hematopoiesis: Updates and Implications at the Solid Tumor-Immune Interface

Buttigieg, M. M., & Rauh, M. J. (2023) · JCO Precision Oncology · doi:10.1200/po.23.00132 · Cited by 30

Role of inflammation and evidence for the use of colchicine in patients with acute coronary syndrome

Bulnes, J. F., González, L., Velásquez, L., Paz, O. M., Venturelli, P. M., & Martínez, G. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1356023 · Cited by 30

Clonal Hematopoiesis and Mutations of Myeloproliferative Neoplasms

Kjær, L. (2020) · Cancers · doi:10.3390/cancers12082100 · Cited by 30

COVID-19 as a mediator of interferon deficiency and hyperinflammation: Rationale for the use of JAK1/2 inhibitors in combination with interferon

Hasselbalch, H. C., Skov, V., Kjær, L., Ellervik, C., Poulsen, A., Poulsen, T. D., & Nielsen, C. H. (2021) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2021.03.006 · Cited by 30

Reprogramming the immunosuppressive tumor microenvironment: exploiting angiogenesis and thrombosis to enhance immunotherapy

Shafqat, A., Omer, M. H., Ahmed, E. N., Mushtaq, A. H., Ijaz, E., Ahmed, Z., AlKattan, K. M., & Yaqinuddin, A. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1200941 · Cited by 32

From Budd-Chiari syndrome to acquired von Willebrand syndrome: thrombosis and bleeding complications in the myeloproliferative neoplasms

Stein, B. L., & Martin, K. A. (2019) · Blood · doi:10.1182/blood.2019001318 · Cited by 30

NETosis in Surgery

James, P., Kaushal, D., & Wilson, R. B. (2024) · Annals of Surgery · doi:10.1097/sla.0000000000006196 · Cited by 29

Vitamin K antagonism impairs the bone marrow microenvironment and hematopoiesis

Verma, D., Kumar, R., Pereira, R. S., Karantanou, C., Zanetti, C., Minciacchi, V. R., Fulzele, K. S., Kunz, K., Hoelper, S., Chahabi, S. Z., et al. (2019) · Blood · doi:10.1182/blood.2018874214 · Cited by 29

Implications of Clonal Hematopoiesis for Precision Oncology

Miller, P. G., & Steensma, D. P. (2020) · JCO Precision Oncology · doi:10.1200/po.20.00144 · Cited by 30

Somatic Mutations and Clonal Hematopoiesis as Drivers of Age-Related Cardiovascular Risk

Haring, B., Wissel, S., & Manson, J. E. (2022) · Current Cardiology Reports · doi:10.1007/s11886-022-01724-2 · Cited by 29

Translating Evidence from Clonal Hematopoiesis to Cardiovascular Disease: A Systematic Review

Papa, V., Marracino, L., Fortini, F., Rizzo, P., Campo, G. C., Vaccarezza, M., & Sega, F. V. D. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9082480 · Cited by 29

Clonal Hematopoiesis and Cardiovascular Outcomes in Older Women

Ezzat, D., Uddin, M. M., Xue, L., Pershad, Y., Zhang, S., Collins, J. M., Kitzman, J. O., Jaiswal, S., Desai, P. M., Kooperberg, C. L., et al. (2025) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2025.07.058 · Cited by 28

Clonal Hematopoiesis and Its Cardiovascular Implications: A Scientific Statement From the American Heart Association

Rhee, J., Bolton, K. L., Gupta, D., Weeks, L. D., Bick, A. G., Tall, A. R., Walsh, K. X., Fuster, J. J., & Natarajan, P. (2026) · Circulation · doi:10.1161/cir.0000000000001404 · Cited by 31

Clonal Hematopoiesis in Hospitalized Elderly Patients With COVID‐19

Hameister, E., Stolz, S. M., Fuhrer, Y., Thienemann, F., Schaer, D. J., Nemeth, J., Schuepbach, R. A., Goede, J. S., Reinhart, S., Schmidt, A. E., et al. (2020) · HemaSphere · doi:10.1097/hs9.0000000000000453 · Cited by 28

The possible role of mutated endothelial cells in myeloproliferative neoplasms

Farina, M., Russo, D., & Hoffman, R. (2021) · Haematologica · doi:10.3324/haematol.2021.278499 · Cited by 28

Association of clonal hematopoiesis mutations with clinical outcomes: A systematic review and meta‐analysis

Nowakowska, M. K., Kim, T., Thompson, M. T., Bolton, K. L., Deswal, A., Lin, S. H., Scheet, P. A., Wehner, M. R., & Nead, K. T. (2022) · American Journal of Hematology · doi:10.1002/ajh.26465 · Cited by 28

Pathogenesis of cardiovascular events in BCR-ABL1-negative myeloproliferative neoplasms

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