PD-1 up-regulation on CD4 + T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production

Celada, Lindsay J.; Kropski, Jonathan A.; Herazo-Maya, Jose D.; Luo, Weifeng; Creecy, Amy; Abad, Andrew T.; Chioma, Ozioma S.; Lee, Grace; Hassell, Natalie E.; Shaginurova, Guzel I.; Wang, Yufen; Johnson, Joyce E.; Kerrigan, Amy; Mason, Wendi R.; Baughman, Robert P.; Ayers, Gregory D.; Bernard, Gordon R.; Culver, Daniel A.; Montgomery, Courtney G.; Maher, Toby M.; Molyneaux, Philip L.; Noth, Imre; Mutsaers, Steven E.; Prele, Cecilia M.; Stokes Peebles, R.; Newcomb, Dawn C.; Kaminski, Naftali; Blackwell, Timothy S.; Van Kaer, Luc; Drake, Wonder P.

doi:10.1126/scitranslmed.aar8356

Cited by 363

The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.

PD-1 up-regulation on CD4 + T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production

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Celada, Lindsay J., Kropski, Jonathan A., Herazo-Maya, Jose D., Luo, Weifeng, Creecy, Amy, Abad, Andrew T., Chioma, Ozioma S., Lee, Grace, Hassell, Natalie E., Shaginurova, Guzel I., Wang, Yufen, Johnson, Joyce E., Kerrigan, Amy, Mason, Wendi R., Baughman, Robert P., Ayers, Gregory D., Bernard, Gordon R., Culver, Daniel A., Montgomery, Courtney G., Maher, Toby M., Molyneaux, Philip L., Noth, Imre, Mutsaers, Steven E., Prele, Cecilia M., Stokes Peebles, R., Newcomb, Dawn C., Kaminski, Naftali, Blackwell, Timothy S., Van Kaer, Luc, Drake, Wonder P.·2018·Science Translational Medicine

DOI 10.1126/scitranslmed.aar8356

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Abstract

PD-1 + T H 17 cells enhance collagen-1 production from human lung fibroblasts.

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55 of 55 references verified0 citation errors · 0 not checkable

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Background
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Authors: Celada, L. J., Kropski, J. A., Herazo-Maya, J. D., Luo, W., Creecy, A., Abad, A. T., Chioma, O. S., Lee, G., Hassell, N. E., Shaginurova, G. I., Wang, Y., Johnson, J. E., Kerrigan, A., Mason, W. R., Baughman, R. P., Ayers, G. D., Bernard, G. R., Culver, D. A., Montgomery, C. G., Maher, T. M., Molyneaux, P. L., Noth, I., Mutsaers, S. E., Prele, C. M., Stokes Peebles, R., Newcomb, D. C., Kaminski, N., Blackwell, T. S., Van Kaer, L., & Drake, W. P.
Venue: Science Translational Medicine
Publisher: American Association for the Advancement of Science (AAAS)
Published: 2018-09-26
Volume: 10
Issue: 460
ISSN: 1946-6234 (ISSN-L)
1946-6242
DOI: 10.1126/scitranslmed.aar8356
OpenAlex: W2892890999
Cited by: 363
References: 55
FWCI: 16.06
Type: journal article
Language: en
Open access: bronze

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This page: CoChat. (2026). Citation check: PD-1 up-regulation on CD4 + T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production. https://app.cochat.ai/papers/10.1126/scitranslmed.aar8356
The paper: Celada, L. J., Kropski, J. A., Herazo-Maya, J. D., Luo, W., Creecy, A., Abad, A. T., Chioma, O. S., Lee, G., Hassell, N. E., Shaginurova, G. I., Wang, Y., Johnson, J. E., Kerrigan, A., Mason, W. R., Baughman, R. P., Ayers, G. D., Bernard, G. R., Culver, D. A., Montgomery, C. G., . . . Drake, W. P. (2018). PD-1 up-regulation on CD4 + T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production. Science Translational Medicine. https://doi.org/10.1126/scitranslmed.aar8356

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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PD-1 up-regulation on CD4 + T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production

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