The DOI matches its Crossref record; 74 of the 75 references it cites were found in a registry or an index.
The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype
Open accessAbstract
Patients with atopic dermatitis and food allergy have an immature epithelial barrier and type 2 immune activation in their skin.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Epithelial barrier dysfunction induces type 2 immune responses and is considered an initial step in developing atopic dermatitis (AD) and the atopic march (14, 16, 17).”
From Particulate matter causes skin barrier dysfunction. (2021) · cites this paper as [17]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
2 retracted
Kelleher, M., Dunn-Galvin, A., Hourihane, J. O., Murray, D., Campbell, L. E., McLean, W. H. I., & Irvine, A. D. (2015) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.12.013 · Cited by 225
RetractedRETRACTED: Skin barrier impairment at birth predicts food allergy at 2 years of age
Kelleher, M. M., Dunn-Galvin, A., Gray, C., Murray, D. M., Kiely, M., Kenny, L., McLean, W. H. I., Irvine, A. D., & Hourihane, J. O. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2015.12.1312 · Cited by 169
RetractedModerated estimation of fold change and dispersion for RNA-seq data with DESeq2
Love, M. I., Huber, W., & Anders, S. (2014) · Genome Biology · doi:10.1186/s13059-014-0550-8 · Cited by 95,106
Trimmomatic: a flexible trimmer for Illumina sequence data
Bolger, A. M., Lohse, M., & Usadel, B. (2014) · Bioinformatics · doi:10.1093/bioinformatics/btu170 · Cited by 65,548
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION
Bligh, E. G., & Dyer, W. J. (1959) · Canadian Journal of Biochemistry and Physiology · doi:10.1139/o59-099 · Cited by 54,751
Classification and Regression by randomForest
Liaw, A. I., & Wiener, M. C. (2007) · Cited by 18,594
mice: Multivariate Imputation by Chained Equations in R
Buuren, S. V., & Groothuis-Oudshoorn, K. (2011) · Journal of Statistical Software · doi:10.18637/jss.v045.i03 · Cited by 13,870
(2010) · University of Twente Research Information · Cited by 6,037
Qgraph: Network visualizations of relationships in psychometric data
Epskamp, S., Cramer, A., Waldorp, L., Schmittmann, V., & Borsboom, D. (2012) · Journal of Statistical Software · doi:10.18637/jss.v048.i04 · Cited by 4,844
Atopic Dermatitis: Global Epidemiology and Risk Factors
Nutten, S. (2015) · Annals of Nutrition and Metabolism · doi:10.1159/000370220 · Cited by 3,124
Research works printed but not linked: 1
- 10.1139/y59-099 · DOI · Paper page
Cited by
Sorted by citations
Establishing microbial composition measurement standards with reference frames
Morton, J. T., Marotz, C., Washburne, A., Silverman, J., Zaramela, L. S., Edlund, A., Zengler, K., & Knight, R. (2019) · Nature Communications · doi:10.1038/s41467-019-10656-5 · Cited by 613
Self-citationComorbidities and the impact of atopic dermatitis
Silverberg, J. I. (2019) · Annals of Allergy, Asthma & Immunology · doi:10.1016/j.anai.2019.04.020 · Cited by 431
Biomarkers in atopic dermatitis—a review on behalf of the International Eczema Council
Renert-Yuval, Y., Thyssen, J. P., Bissonnette, R., Bieber, T., Kabashima, K., Hijnen, D., & Guttman-Yassky, E. (2021) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2021.01.013 · Cited by 350
Skin bioelectronics towards long-term, continuous health monitoring
Wang, Y., Haick, H., Guo, S., Wang, C., Lee, S., Yokota, T., & Someya, T. (2022) · Chemical Society Reviews · doi:10.1039/d2cs00207h · Cited by 328
The role of filaggrin in atopic dermatitis and allergic disease
Drislane, C., & Irvine, A. D. (2019) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2019.10.008 · Cited by 322
Metadata
- Authors
- Leung, D. Y. M., Calatroni, A., Zaramela, L. S., LeBeau, P. K., Dyjack, N., Brar, K., David, G., Johnson, K., Leung, S., Ramirez-Gama, M., Liang, B., Rios, C., Montgomery, M. T., Richers, B. N., Hall, C. F., Norquest, K. A., Jung, J., Bronova, I., Kreimer, S., Conover Talbot, C., Crumrine, D., Cole, R. N., Elias, P., Zengler, K., Seibold, M. A., Berdyshev, E., & Goleva, E.
- Affiliations
- National Jewish Health (US)
- Rho (United States) (US)
- University of California San Diego (US)
- Johns Hopkins University (US)
- Johns Hopkins University, Baltimore, MD 21218, USA.
- University of California, San Francisco (US)
- Corresponding author
- Leung, Donald Y. M.
- ORCID
- Leung, Donald Y. M.
- Calatroni, Agustin
- Zaramela, Livia S.
- LeBeau, Petra K.
- Dyjack, Nathan
- Brar, Kanwaljit
- David, Gloria
- Ramirez-Gama, Marco
- Liang, Bo
- Montgomery, Michael T.
- Hall, Clifton F.
- Norquest, Kathryn A.
- Jung, John
- Bronova, Irina
- Kreimer, Simion
- Conover Talbot, C.
- Crumrine, Debra
- Cole, Robert N.
- Elias, Peter
- Zengler, Karsten
- Seibold, Max A.
- Berdyshev, Evgeny
- Goleva, Elena
- Venue
- Science Translational Medicine
- Published
- 2019-02-20
- Volume
- 11
- Issue
- 480
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC7676854
- OpenAlex
- W2916319738
- Cited by
- 214
- References
- 75
- Citations by year
- 2026: 10 · 2025: 19 · 2024: 38 · 2023: 29 · 2022: 29 · 2021: 37 · 2020: 39 · 2019: 12
- FWCI
- 29.47
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIH/NIAID Atopic Dermatitis Research Network (U19AI117673, UM2AI117870)
- NIH/NCATS Colorado CTSA (UL1 TR002535)
- Topics
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
- Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
- Keywords
- atopic dermatitis, food allergy, endotypes, non-lesional skin, skin barrier, Th2 immune response, epithelial barrier function
- MeSH terms
- Filaggrin Proteins, Adolescent, Child, Child, Preschool, Dendritic Cells, Dermatitis, Atopic, Epidermis, Food Hypersensitivity, Humans, Intermediate Filament Proteins, Keratins, Lipids, Skin, Water Loss, Insensible, Area Under Curve, Surgical Tape, Transcriptome, Microbiota
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
