Leung, Donald Y.M.

Endogenous Antimicrobial Peptides and Skin Infections in Atopic Dermatitis

Ong, P. Y., Ohtake, T., Brandt, C., Strickland, I., Boguniewicz, M., Ganz, T., Gallo, R. L., & Leung, D. Y. M. (2002) · New England Journal of Medicine

Antimicrobial Peptides and ActivitiesDermatology and Skin Diseases

Cited by 1,960

New insights into atopic dermatitis

Leung, D. Y. M., Boguniewicz, M., Howell, M. D., Nomura, I., & Hamid, Q. A. (2004) · Journal of Clinical Investigation

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 1,435

Filaggrin Mutations Associated with Skin and Allergic Diseases

Irvine, A. D., McLean, W. H. I., & Leung, D. Y. M. (2011) · New England Journal of Medicine

Dermatology and Skin DiseasesSkin and Cellular Biology Research

Cited by 1,217

Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis

Nakatsuji, T., Chen, T. H., Narala, S., Chun, K. A., Two, A. M., Yun, T., Shafiq, F., Kotol, P. F., Bouslimani, A., Melnik, A. V., et al. (2017) · Science Translational Medicine

Dermatology and Skin DiseasesAntimicrobial Resistance in Staphylococcus

Cited by 1,095

Cytokine modulation of atopic dermatitis filaggrin skin expression

Howell, M. D., Kim, B. E., Gao, P., Grant, A. V., Boguniewicz, M., DeBenedetto, A., Schneider, L., Beck, L. A., Barnes, K. C., & Leung, D. Y. M. (2007) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 1,084

Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6

Kim, B. E., Leung, D. Y. M., Boguniewicz, M., & Howell, M. D. (2008) · Clinical Immunology

Dermatology and Skin DiseasesCytokine Signaling Pathways and Interactions

Cited by 538

Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report

Akdis, C. A., Akdis, M., Bieber, T., Bindslev-Jensen, C., Boguniewicz, M., Eigenmann, P., Hamid, Q., Kapp, A., Leung, D. Y. M., Lipozencic, J., et al. (2006) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesAsthma and respiratory diseases

Cited by 460

Significance of Skin Barrier Dysfunction in Atopic Dermatitis

Kim, B. E., & Leung, D. Y. M. (2018) · Allergy, Asthma & Immunology Research

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 393

The Effects of Airway Microbiome on Corticosteroid Responsiveness in Asthma

Goleva, E., Jackson, L. P., Harris, J. K., Robertson, C. E., Sutherland, E. R., Hall, C. F., Good, J. T., Gelfand, E. W., Martin, R. J., & Leung, D. Y. M. (2013) · American Journal of Respiratory and Critical Care Medicine

Asthma and respiratory diseasesGut microbiota and health

Cited by 363

Development of a human skin commensal microbe for bacteriotherapy of atopic dermatitis and use in a phase 1 randomized clinical trial

Nakatsuji, T., Hata, T. R., Tong, Y., Cheng, J. Y., Shafiq, F., Butcher, A. M., Salem, S. S., Brinton, S. L., Rudman Spergel, A. K., Johnson, K., et al. (2021) · Nature Medicine

Dermatology and Skin DiseasesAntimicrobial Resistance in Staphylococcus

Cited by 333

The microbiome in allergic disease: Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology

Huang, Y. J., Marsland, B. J., Bunyavanich, S., O'Mahony, L., Leung, D. Y. M., Muraro, A., & Fleisher, T. A. (2017) · Journal of Allergy and Clinical Immunology

Asthma and respiratory diseasesGut microbiota and health

Cited by 330

Onset and persistence of childhood asthma: predictors from infancy

Klinnert, M. D., Nelson, H. S., Price, M. R., Adinoff, A. D., Leung, D. Y. M., & Mrazek, D. A. (2001) · Pediatrics

Asthma and respiratory diseasesOccupational exposure and asthma

Cited by 292

Lipid abnormalities in atopic skin are driven by type 2 cytokines

Berdyshev, E., Goleva, E., Bronova, I., Dyjack, N., Rios, C., Jung, J., Taylor, P., Jeong, M., Hall, C. F., Richers, B. N., et al. (2018) · JCI Insight

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 283

Epicutaneous sensitization in the development of food allergy: what is the evidence and how can this be prevented?

Brough, H. A., Nadeau, K. C., Sindher, S. B., Alkotob, S. S., Chan, S., Bahnson, H. T., Leung, D. Y. M., & Lack, G. (2020) · Allergy

Food Allergy and Anaphylaxis ResearchDermatology and Skin Diseases

Cited by 275

Epithelial barrier repair and prevention of allergy

Goleva, E., Berdyshev, E., & Leung, D. Y. M. (2019) · Journal of Clinical Investigation

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 251

TNF-α Downregulates Filaggrin and Loricrin through c-Jun N-terminal Kinase: Role for TNF-α Antagonists to Improve Skin Barrier

Kim, B. E., Howell, M. D., Guttman, E., Gilleaudeau, P. M., Cardinale, I. R., Boguniewicz, M., Krueger, J. G., & Leung, D. Y. M. (2011) · Journal of Investigative Dermatology

Psoriasis: Treatment and PathogenesisDermatology and Skin Diseases

Cited by 239

Th2 Cytokines Act on S100/A11 to Downregulate Keratinocyte Differentiation

Howell, M. D., Fairchild, H. R., Kim, B. E., Bin, L., Boguniewicz, M., Redzic, J. S., Hansen, K. C., & Leung, D. Y. M. (2008) · Journal of Investigative Dermatology

Dermatology and Skin DiseasesS100 Proteins and Annexins

Cited by 224

The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype

Leung, D. Y. M., Calatroni, A., Zaramela, L. S., LeBeau, P. K., Dyjack, N., Brar, K., David, G., Johnson, K., Leung, S., Ramirez-Gama, M., et al. (2019) · Science Translational Medicine

Dermatology and Skin DiseasesFood Allergy and Anaphylaxis Research

Cited by 214

Mechanism of HBD-3 deficiency in atopic dermatitis

Howell, M. D., Boguniewicz, M., Pastore, S., Novak, N., Bieber, T., Girolomoni, G., & Leung, D. Y. M. (2006) · Clinical Immunology

Dermatology and Skin DiseasesAntimicrobial Peptides and Activities

Cited by 208

Interleukin-10 Downregulates Anti-Microbial Peptide Expression in Atopic Dermatitis

Howell, M. D., Novak, N., Bieber, T., Pastore, S., Girolomoni, G., Boguniewicz, M., Streib, J., Wong, C., Gallo, R. L., & Leung, D. Y. M. (2005) · Journal of Investigative Dermatology

Dermatology and Skin DiseasesAntimicrobial Peptides and Activities

Cited by 193

Cutaneous barrier dysfunction in allergic diseases

Leung, D. Y. M., Berdyshev, E., & Goleva, E. (2020) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 190

Particulate matter causes skin barrier dysfunction.

Kim, B. E., Kim, J., Goleva, E., Berdyshev, E., Lee, J., Vang, K. A., Lee, U. H., Han, S., Leung, S., Hall, C. F., et al. (2021) · JCI insight

Dermatology and Skin DiseasesAir Quality and Health Impacts

Cited by 173

The skin microbiome is different in pediatric versus adult atopic dermatitis

Shi, B., Bangayan, N. J., Curd, E., Taylor, P. A., Gallo, R. L., Leung, D. Y. M., & Li, H. (2016) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 161

Allergic skin diseases

Fonacier, L. S., Dreskin, S. C., & Leung, D. Y. M. (2010) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 139