Cited by 36Muscle Physiology and DisordersNutrition and Health in AgingIon channel regulation and function

An embryonic CaVβ1 isoform promotes muscle mass maintenance via GDF5 signaling in adult mouse

Open access
Traoré, Massiré, Gentil, Christel, Benedetto, Chiara, Hogrel, Jean-Yves, De la Grange, Pierre, Cadot, Bruno, Benkhelifa-Ziyyat, Sofia, Julien, Laura +4 more·2019·Science Translational Medicine

Abstract

CaVβ1E boosts downstream growth differentiation factor 5 signaling to counteract muscle mass loss in denervated or aged mouse muscles.

Integrity signals

Registry

Crossref · 10.1126/scitranslmed.aaw1131

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52 of 52 references verified0 citation errors · 0 not checkable

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Authors
Traoré, M., Gentil, C., Benedetto, C., Hogrel, J.-Y., De la Grange, P., Cadot, B., Benkhelifa-Ziyyat, S., Julien, L., Lemaitre, M., Ferry, A., Piétri-Rouxel, F., & Falcone, S.
Affiliations
  • Inovarion (France) (FR)
  • Inserm (FR)
  • Institut de Myologie (FR)
  • GenoSplice, F-75005 Paris, France.
  • Sorbonne Université, Centre de Recherche en Myologie, UM76, INSERM U974, Institut de Myologie, F-75013, Paris, France.
  • Sorbonne Université, INSERM, UMS28, F-75013 Paris, France.
Corresponding author
  • Traoré, Massiré
  • Gentil, Christel
  • Falcone, Sestina
Venue
Science Translational Medicine
Published
2019-11-06
Volume
11
Issue
517
ISSN
  • 1946-6234 (ISSN-L)
  • 1946-6242
OpenAlex
W2985330064
Cited by
36
References
52
Citations by year
2026: 6 · 2025: 7 · 2024: 4 · 2023: 5 · 2022: 4 · 2021: 7 · 2020: 3
FWCI
1.16
Type
journal article
Language
en
Open access
Licence
other-oa
Locations
  • Science Translational Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • HAL (submittedVersion, other-oa)
  • HAL (submittedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
  • Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion channel regulation and function
Keywords
sarcopenia, muscle denervation, sciatic nerve, excitation-contraction coupling, muscle innervation, muscle aging, muscle atrophy
MeSH terms
Adult, Aged, Aged, 80 and over, Aging, Animals, Atrophy, Denervation, Embryo, Mammalian, Exons, Female, Humans, Male, Muscles, Neuromuscular Junction, Organ Size, Physical Conditioning, Animal, RNA Splicing, Signal Transduction, Gene Expression Regulation, Developmental, Protein Isoforms, Calcium Channels, L-Type, Mice, Growth Differentiation Factor 5, Young Adult

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