Cited by 433Antibiotic Resistance in BacteriaAntimicrobial Resistance in StaphylococcusBacterial Genetics and Biotechnology

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Mechanisms of Antibiotic Resistance

Munita, Jose M., Arias, Cesar A.·2016·Virulence Mechanisms of Bacterial Pathogens

DOI 10.1128/9781555819286.ch17

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Abstract

The discovery, commercialization, and routine administration of antimicrobial compounds to treat infections revolutionized modern medicine and changed the therapeutic paradigm. Indeed, antibiotics have become one of the most important medical interventions needed for the development of complex medical approaches such as cutting-edge surgical procedures, solid organ transplantation, and management of patients with cancer, among others. Unfortunately, the marked increase in antimicrobial resistance among common bacterial pathogens is now threatening this therapeutic accomplishment, jeopardizing the successful outcomes of critically ill patients. In fact, the World Health Organization has named antibiotic resistance as one of the three most important public health threats of the 21st century (1).

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Authors: Munita, J. M., & Arias, C. A.
Affiliations: Universidad del Desarrollo (CL)
Department of Internal Medicine, Division of Infectious Diseases; University of Texas Medical School at Houston; Houston TX 77030
ORCID: Munita, Jose M.
Venue: Virulence Mechanisms of Bacterial Pathogens
Publisher: ASM Press
Published: 2016-04-09
Pages: 481-511
DOI: 10.1128/9781555819286.ch17
OpenAlex: W4211042139
Cited by: 421
References: 106
Citations by year: 2026: 57 · 2025: 71 · 2024: 87 · 2023: 44 · 2022: 42 · 2021: 50 · 2020: 36 · 2019: 21 · 2018: 9 · 2017: 3 · 2016: 1
FWCI: 15.59
Type: book chapter
Language: en
Open access: closed
Locations: ASM Press eBooks (publishedVersion)
Topics: Health Sciences › Medicine › Microbiology (medical) › Antibiotic Resistance in Bacteria
Health Sciences › Medicine › Infectious Diseases › Antimicrobial Resistance in Staphylococcus
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
Keywords: antibiotic resistance, antibiotic resistance mechanisms, pathogenic bacteria, antimicrobial agents, public health risk, critically ill patients

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