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Mechanisms of Antibiotic Resistance
Abstract
The discovery, commercialization, and routine administration of antimicrobial compounds to treat infections revolutionized modern medicine and changed the therapeutic paradigm. Indeed, antibiotics have become one of the most important medical interventions needed for the development of complex medical approaches such as cutting-edge surgical procedures, solid organ transplantation, and management of patients with cancer, among others. Unfortunately, the marked increase in antimicrobial resistance among common bacterial pathogens is now threatening this therapeutic accomplishment, jeopardizing the successful outcomes of critically ill patients. In fact, the World Health Organization has named antibiotic resistance as one of the three most important public health threats of the 21st century (1).
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Metadata
- Authors
- Munita, J. M., & Arias, C. A.
- Affiliations
- Universidad del Desarrollo (CL)
- Department of Internal Medicine, Division of Infectious Diseases; University of Texas Medical School at Houston; Houston TX 77030
- ORCID
- Munita, Jose M.
- Venue
- Virulence Mechanisms of Bacterial Pathogens
- Publisher
- ASM Press
- Published
- 2016-04-09
- Pages
- 481-511
- OpenAlex
- W4211042139
- Cited by
- 421
- References
- 106
- Citations by year
- 2026: 57 · 2025: 71 · 2024: 87 · 2023: 44 · 2022: 42 · 2021: 50 · 2020: 36 · 2019: 21 · 2018: 9 · 2017: 3 · 2016: 1
- FWCI
- 15.59
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- ASM Press eBooks (publishedVersion)
- Topics
- Health Sciences › Medicine › Microbiology (medical) › Antibiotic Resistance in Bacteria
- Health Sciences › Medicine › Infectious Diseases › Antimicrobial Resistance in Staphylococcus
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
- Keywords
- antibiotic resistance, antibiotic resistance mechanisms, pathogenic bacteria, antimicrobial agents, public health risk, critically ill patients
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