The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Action of Disinfectant Quaternary Ammonium Compounds against Staphylococcus aureus
Open accessAbstract
Mode-of-action studies concluded that alkyldimethylbenzylammonium chloride (ADBAC) (a blend of C 12, C 14 and C 16 alkyl homologues) and didecyldimethylammonium chloride (DDAC) are both membrane-active agents, possessing subtly different modes of action reflecting early cell interactions against Staphylococcus aureus. ADBAC and DDAC exhibited similar MIC behaviors from 0.4 ppm to 1.8 ppm over an inoculum range of 1 × 10 5 to 1 × 10 9 CFU/ml at 35°C. For ADBAC and DDAC, an increased rapidity of killing against S. aureus(final concentration, 2 × 10 9 CFU/ml) was observed at 35°C compared to 25°C. Concentration exponents (η) for killing were <2.5 for both agents, and temperature influenced the η value. Examination of leakage and kill data suggested that a single leakage marker was not indicative of cell death. ADBAC and DDAC possessed Langmuir (L4) and high-affinity (H3/4) uptake isotherms, respectively. ADBAC molecules formed a single monolayer of coverage of cells at the end of primary uptake, and DDAC formed a double monolayer. Rapid cell leakage occurred at bactericidal concentrations, with total depletion of the intracellular potassium and 260-nm-absorbing pools released in this strict order. Autolysis was observed for ADBAC and DDAC at concentrations of 9 μg/ml (0.0278 mM and 0.0276 mM, respectively) and above, together with the depletion of approximately 30% of the internal potassium pool. Autolysis contributed to ADBAC and DDAC lethality, although high biocide concentrations may have inhibited autolytic enzyme activity.
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Cites
A general treatment and classification of the solute adsorption isotherm. I. Theoretical
Giles, C. H., Smith, D., & Huitson, A. (1974) · Journal of Colloid and Interface Science · doi:10.1016/0021-9797(74)90252-5 · Cited by 1,996
Chapter III Chemical Analysis of Microbial Cells
Herbert, D., Phipps, P. J., & Strange, R. E. (1971) · Methods in Microbiology · doi:10.1016/s0580-9517(08)70641-x · Cited by 1,274
Manual of Microbiological Methods
Porter, J. R., & Conn, H. J. (1958) · AIBS Bulletin · doi:10.2307/1291949 · Cited by 589
Triclosan: a widely used biocide and its link to antibiotics
Schweizer, H. (2001) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(01)00273-7 · Cited by 447
Disinfectant resistance mechanisms, cross-resistance, and co-resistance
Chapman, J. S. (2003) · International Biodeterioration & Biodegradation · doi:10.1016/s0964-8305(03)00044-1 · Cited by 437
Mechanisms of action of disinfectants
Denyer, S. P., & Stewart, G. S. A. B. (1998) · International Biodeterioration & Biodegradation · doi:10.1016/s0964-8305(98)00023-7 · Cited by 420
Self-citationMechanisms of action of antibacterial biocides
Denyer, S. P. (1995) · International Biodeterioration & Biodegradation · doi:10.1016/0964-8305(96)00015-7 · Cited by 324
Self-citationBacterial disinfectant resistance - a challenge for the food industry
Langsrud, S., Sidhu, M. S., Heir, E., & Holck, A. L. (2003) · International Biodeterioration & Biodegradation · doi:10.1016/s0964-8305(03)00039-8 · Cited by 214
HUGO, W. B., & LONGWORTH, A. R. (1966) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1966.tb07935.x · Cited by 183
SALTON, M. R. J. (1951) · Journal of General Microbiology · doi:10.1099/00221287-5-2-391 · Cited by 175
Cited by
Buffet-Bataillon, S., Tattevin, P., Bonnaure-Mallet, M., & Jolivet-Gougeon, A. (2012) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2012.01.011 · Cited by 601
Bacterial Biofilm Eradication Agents: A Current Review
Verderosa, A. D., Totsika, M., & Fairfull-Smith, K. E. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00824 · Cited by 555
Microbiologically influenced corrosion and current mitigation strategies: A state of the art review
Jia, R., Unsal, T., Xu, D., Lekbach, Y., & Gu, T. (2019) · International Biodeterioration & Biodegradation · doi:10.1016/j.ibiod.2018.11.007 · Cited by 503
Jain, A., Duvvuri, L. S., Farah, S., Beyth, N., Domb, A. J., & Khan, W. (2014) · Advanced Healthcare Materials · doi:10.1002/adhm.201400418 · Cited by 485
Cosmetics preservation: a review on present strategies
Halla, N., Fernandes, I. P., Heleno, S. A., Costa, P., Boucherit-Otmani, Z., Boucherit, K., Rodrigues, A. E., Ferreira, I. C. F. R., & Barreiro, M. F. (2018) · Molecules · doi:10.3390/molecules23071571 · Cited by 401
Metadata
- Authors
- Ioannou, C. J., Hanlon, G. W., & Denyer, S. P.
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 2007-01
- Volume
- 51
- Issue
- 1
- Pages
- 296-306
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- OpenAlex
- W2079266092
- Cited by
- 377
- References
- 30
- FWCI
- 1.60
- Type
- journal article
- Language
- en
- Open access
- green
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