Fks1 and Fks2 Are Functionally Redundant but Differentially Regulated in Candida glabrata: Implications for Echinocandin Resistance

Katiyar, Santosh K., Alastruey-Izquierdo, Ana, Healey, Kelley R., Johnson, Michael E., Perlin, David S., Edlind, Thomas D.·2012·Antimicrobial Agents and Chemotherapy

Cited by (147)

Items 101–147 of 147

  1. Microevolution of Candida glabrata (Nakaseomyces glabrata) during an infection
    Ana L. López-Marmolejo, Marco J. Hernández-Chávez, Guadalupe Gutiérrez‐Escobedo, M. Selene Herrera-Basurto, Hector Manuel Mora-Montes, Alejandro De Las Peñas, Irene Castaño · 2024 · Fungal Genetics and Biology
  2. Review of the Current Management of Urinary Tract Infections due to Fluconazole-Resistant and Non-Albicans Candida Species
    X. Tan, K. Baugh, Zackery P. Bulman, Eric Wenzler · 2020 · Current Fungal Infection Reports
  3. Caspofungin resistance in Candia auris due to mutations in Fks 1 with adjunctive role of chitin and key cell wall stress response pathway genes
    Dipti Sharma, Raees Ahmad Paul, Arunaloke Chakrabarti, Sanjay Bhattacharya, Rajeev N. Soman, Shamanth Adekhandi Shankarnarayan, Dipali Chavan, Shreya Singh, Parijit Das, Harsimran Kaur et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  4. Update on Antifungal Resistance and its Clinical Impact
    Brunella Posteraro, Patrizia Posteraro, Maurizio Sanguinetti · 2013 · Current Fungal Infection Reports
  5. The secreted acid trehalase encoded by the CgATH1 gene is involved in Candida glabrata virulence
    Rafael Garcia Lopes, Julian Esteban Muñoz, Ludmila M Barros, Sérgio Luiz Alves Júnior, Carlos P. Taborda, Boris U. Stambuk · 2020 · Memórias do Instituto Oswaldo Cruz
  6. Echinocandin tolerance and persistence in vitro are regulated by calcineurin signaling in Candida glabrata
    Harrington, Abigail A., Nickels, Timothy J., Cunningham, Kyle W. · 2026 · mBio
  7. Expression of 1,3-β-glucan synthase subunits in Candida glabrata is regulated by the cell cycle and growth conditions and at both transcriptional and post-transcriptional levels
    Gonzalez-Jimenez, Irene, Keniya, Mikhail V., Aptekmann, Ariel A., Quinteros, Christopher, Wilkerson, Alexis, Arastehfar, Amir, Daneshnia, Farnaz, Perlin, David S., Shor, Erika · 2025 · Antimicrobial Agents and Chemotherapy
  8. Multidrug- and Cross-Resistant Candida: the Looming Threat
    Michaela Lackner, Adela Martín‐Vicente, Cornelia Lass‐Flörl · 2014 · Current Fungal Infection Reports
  9. BASES DA RESISTÊNCIA ANTIFÚNGICA: UMA REVISÃO COMENTADA
    Caroline Berto, Fernanda Wirth, Natália Barth, Djuli Milene Hermes · 2018 · Revista Uningá
  10. Fungicide resistance in Fusarium oxysporum: Advances in molecular, cellular, and metabolic mechanisms
    Erisneida Campos-Jiménez, Ricardo Rodríguez-Vargas, Elías Trujillo‐Esquivel, Martín Orlando Camargo-Escalante, Ernestina Castro‐Longoria, Domingo Martínez‐Soto · 2026 · Physiological and Molecular Plant Pathology
  11. Molecular detection of antimicrobial resistance
    Priyanka Uprety, Thomas J. Kirn · 2024 · Elsevier eBooks
  12. Analysis of fks1 and fks2 gene mutations in invasive Candida glabrata strains from Pakistan
    Saba Memon, Najia Karim Ghanchi, Urooj Zafar, Joveria Qais Farooqi, Sadaf Zaka, Kauser Jabeen · 2022 · Mycoses
  13. Community‐Onset Fungemias: Epidemiology and Genomic Characterization at a Tertiary‐Care Hospital in Barcelona, Spain
    Batista, Celso Soares Pereira, Rivera, Alba, Alvarez Albarran, Maria Teresa, Rubio, Marc, Belen-Figas, Iris, Lopez-Querol, Cristina, Miró, Elisenda, Navarro, Ferran, Sanchez-Reus, Ferran · 2025 · Journal of Fungi
  14. Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
    Bikash Baral · 2026 · ChemFoodChem
  15. BASES DA RESISTÊNCIA ANTIFÚNGICA: UMA REVISÃO COMENTADA
    Caroline Berto, Djuli Milene Hermes · 2023 · Editora Científica Digital eBooks
  16. Molecular Characterization and In Vitro Antifungal Susceptibility of Candida Glabrata Clinical Isolates with Reduced Echinocandin Susceptibility and High Level Multi-Azole Resistance
    Jose A Vazquez Dwayne Baxa · 2014 · Clinical Microbiology Open Access
  17. Lipidomics Approaches: Applied to the Study of Pathogenesis in Candida Species
    Ashutosh Singh, Nitesh Khandelwal, Rajendra Prasad · 2019 · Progress in molecular and subcellular biology
  18. Mechanisms of Resistance to Antifungal Agents
    David S. Perlin · 2023 · ClinMicroNow
  19. Unveiling the cell wall-targeting mechanisms and multifaceted virulence modulation by a eugenol glycoconjugate against Aspergillus fumigatus: insights from in vitro and in ovo studies
    Lovely Gupta, Shalini Verma, Lakshmi Goswami, Himanshu Kamboj, Pooja Sen, Asish K. Bhattacharya, Pooja Vijayaraghavan · 2024 · Journal of Applied Microbiology
  20. The histone deubiquitinase Ubp10 modulates stress response, drug resistance, and virulence in Candida glabrata
    Y. Y. Chou, Yi-Hang Lee, Li-Hang Hsu, Yuehan Huang, Ying‐Lien Chen · 2025 · Medical Mycology
  21. Microbial heterogeneity-mediated treatment evasion and the potential for engineered live biotherapeutic products
    Eli G. Cytrynbaum, Megan N. McClean · 2025 · Advanced Drug Delivery Reviews
  22. Uncovering actionable trade-offs of antifungal resistance in a yeast pathogen
    Juan Carlos Nunez‐Rodriguez, Miquel Àngel Schikora-Tamarit, Toni Gabaldón · 2026 · Molecular Systems Biology
  23. Population genomics reveals environmental reservoirs and antifungal resistance mechanisms in major non-albicans Candida species
    Yuhang Zhang, Xiaomin Yang, Shuang Wang, Jian‐Qiang Su, Yong‐Guan Zhu · 2026 · Journal of Environmental Sciences
  24. Some issues of the resistance of Candida glabrata to echinocandins
    Alexander V. Veselov · 2019 · Clinical Microbiology and Antimicrobial Chemotherapy
  25. Mechanisms of Resistance to Antifungal Agents
    David S. Perlin · 2023 · ClinMicroNow
  26. Molecular basis of enfumafungin inhibition and resistance in Candida glabrata β-1,3-Glucan synthase FKS1
    Ping Yang, Chu Qi, Shuchang Du, Xinlin Hu, Zhengkang Hua, Yizheng Yang, Di Zhang, Yan Ke, Mingjie Zhang, Xiaotian Liu et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  27. Les échinocandines : mise au point
    B. Pilmis, Amanda Lopes, Olivier Lortholary, Caroline Charlier · 2013 · Journal des Anti-infectieux
  28. Heroin with a Twist: Candida Glabrata Endocarditis Concurrent with Brain Mycetomas in an IV Drug User
    George Z. Panos · 2017 · Journal of Microbiology & Experimentation
  29. Sistemik Aspergillosis ve Kandidiyazisin Tedavisinde Ekinokandin Grubu Antimikotiklerin Etkinliği ve Veteriner Hekimliğindeki Yeri
    Belgi NASİBOĞLU, Banu Dokuzeylül, Fatma Ateş Alkan, Ümit Bora Barutçu, Mehmet Erman Or · 2018 · Journal of Advances in VetBio Science and Techniques
  30. Fungal Infections Complicating COVID-19
    Hoenigl, Martin, Talento, Alida Fe · 2021 · MDPI eBooks
  31. Duplication and overexpression of the genes encoding a beta 1,3-glucan synthase confer the intrinsic resistance to echinocandin in Mucor circinelloides
    Alexis Garcia, Eun Young Huh, Soo Chan Lee · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  32. Echinocandin Resistance
    David S. Perlin · 2017 · Springer eBooks
  33. Ciências Biológicas e da Saúde: integrando saberes em diferentes contextos - Volume 3
    Barbosa Neto, Octávio, Marcus Fernando da Silva Praxedes, Silva, Patrício Francisco da, Carvalho Junior, Fábio Ferreira de · 2023 · Editora Científica Digital eBooks
  34. New insights into the echinocandin resistance in Candida spp. in the clinical setting
    Antoine Gedeon, Yasmine Kalboussi, Jeanne Bigot, Vicky Le, Éric Dannaoui, Sandra Vellaissamy, Marie Antignac, S. Petrella, C. Hennequin, J. Guitard · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  35. Az antifungális rezisztencia kialakulásának és következményének vizsgálata a humánpatogén Candida auris esetében
    Flóra Bohner · 2024 · SZTE Repository of Dissertations (University of Szeged)
  36. Mitochondrial defects result in decreased susceptibility to echinocandins via the transcriptional regulator Pdr1 in Candida glabrata
    Natalia G. Klimova, H. Patel, Frédéric Devaux, Bernard Turcotte · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  37. Rezafungin: A β-(1,3)-D-glucan synthase inhibitor as antifungal drug derived from Echinocandin B0
    Haowen Luo, Yingda Zang, Dongming Zhang · 2025 · Elsevier eBooks
  38. A Calcineurin Inhibitor as an Enhancer of Candida Susceptibility to Anidulafungin
    Irene Rovira, Edurne Montemayor, Sandra Gil-Alonso, Katherine Miranda-Cadena, F Sánchez, Guillermo Quindós, Elena Eraso, Nerea Jauregizar · 2026 · ACS Omega
  39. Antifungal drug resistance: Current mechanisms and future directions
    Mengjun Tang, Liangsheng Fan, Liang Shen, Hui Xing · 2026 · Elsevier eBooks
  40. Characterization of the nuclear RNase P of Candida glabrata and improvement of genome editing tools
    Yacine Dahman · 2018 · theses.fr (ABES)
  41. Estudio proteómico y efecto de la modulación de la vía Calmodulina/Calcineurina en aislamientos de Candida glabrata resistentes a caspofungina
    Carlos Andres Ceballos Garzón · 2021 · theses.fr (ABES)
  42. Antifungal susceptibility, FKS1 gene expression, and virulence determinants of Candida albicans in pediatric and neonatal candidiasis
    Mandana Rezaei-Mojaz, Hanie Hajghafari, Masoomeh Shams‐Ghahfarokhi, Sima Sadat Seyedjavadi, Zahra Salehi, Ali Eslamifar, Fatemehsadat Jamzivar, Mehdi Razzaghi‐Abyaneh · 2026 · BMC Infectious Diseases
  43. Prioritisation of Lichen-derived metabolites targeting multi-drug-resistant proteins of Candida auris and Candida albicans through cheminformatics
    Priyadarshi Saha, Khumjar Debbarma, Akash Rathinam, Swagatam Das, Padmanaban Velayudhaperumal Chellam · 2026 · Journal of the Indian Chemical Society
  44. Slt2 kinase of the cell wall integrity pathway is required for Fks2-specific echinocandin resistance in Candida glabrata
    Zubayeda Uddin, Saira Tahsin, Klára Valíčková, Tengfei Long, Laura Fruhauf De Macedo, Gabrielle Popencuk, Yanan Zhao, Kelley R. Healey · 2026 · Microbiology Spectrum
  45. Parallel evolution under constraint shapes echinocandin resistance in Candida auris
    Nicholas C. Cauldron, Erika N. Dort, Garrett Weeks, Phillip David Rogers, Christina A. Cuomo · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  46. A gene network regulating echinocandin heteroresistance in Candida glabrata
    Abigail A. Harrington, Kyle W. Cunningham · 2026 · Antimicrobial Agents and Chemotherapy
  47. Fungal resistance to echinocandins and the MDR phenomenon in Candida glabrata
    Healey, Kelley, Perlin, David S · 2018