Acquired flucytosine resistance during combination therapy with caspofungin and flucytosine for Candida glabrata cystitis

ESCMID* guideline for the diagnosis and management of Candida diseases 2012: non-neutropenic adult patients

Cornely, O. A., Bassetti, M., Calandra, T., Garbino, J., Kullberg, B. J., Lortholary, O., Meersseman, W., Akova, M., Arendrup, M. C., Arikan-Akdagli, S., et al. (2012) · Clinical Microbiology and Infection · doi:10.1111/1469-0691.12039 · Cited by 1,217 · see citing works

Echinocandin antifungal drugs

Denning, D. W. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14472-8 · Cited by 1,131 · see citing works

Candida Urinary Tract Infections—Treatment

Fisher, J. F., Sobel, J. D., Kauffman, C. A., & Newman, C. A. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir112 · Cited by 214 · see citing works

A Multicenter, Double‐Blind Trial of a High‐Dose Caspofungin Treatment Regimen versus a Standard Caspofungin Treatment Regimen for Adult Patients with Invasive Candidiasis

Betts, R. F., Nucci, M., Talwar, D., Gareca, M., Queiroz‐Telles, F., Bedimo, R. J., Herbrecht, R., Ruiz‐Palacios, G., Young, J. H., Baddley, J. W., et al. (2009) · Clinical Infectious Diseases · doi:10.1086/598933 · Cited by 214 · see citing works

The Candida genome database incorporates multiple Candida species: multispecies search and analysis tools with curated gene and protein information for Candida albicans and Candida glabrata

Inglis, D. O., Arnaud, M. B., Binkley, J., Shah, P., Skrzypek, M. S., Wymore, F., Binkley, G., Miyasato, S. R., Simison, M., & Sherlock, G. J. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr945 · Cited by 194 · see citing works

Multilocus Sequence Typing of Candidaglabrata Reveals Geographically EnrichedClades

Dodgson, A. R., Pujol, C., Denning, D. W., Soll, D. R., & Fox, A. J. (2003) · Journal of Clinical Microbiology · doi:10.1128/jcm.41.12.5709-5717.2003 · Cited by 191 · see citing works

Acquisition of Flucytosine, Azole, and Caspofungin Resistance in Candida glabrata Bloodstream Isolates Serially Obtained from a Hematopoietic Stem Cell Transplant Recipient

Chapeland‐Leclerc, F., Hennequin, C., Papon, N., Noël, T., Girard, A., Socié, G., Ribaud, P., & Lacroix, C. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01138-09 · Cited by 104 · see citing works

Caspofungin in the Treatment of Symptomatic Candiduria

Sobel, J. D., Bradshaw, S. K., Lipka, C. J., & Kartsonis, N. A. (2007) · Clinical Infectious Diseases · doi:10.1086/510432 · Cited by 101 · see citing works

Mutational Analysis of Flucytosine Resistance in Candida glabrata

Edlind, T. D., & Katiyar, S. K. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00605-10 · Cited by 84 · see citing works

Development of Resistance to 5-Fluorocytosine in Candida parapsilosis during Therapy

Hoeprich, P. D., Ingraham, J. L., Kleker, E., & Winship, M. J. (1974) · The Journal of Infectious Diseases · doi:10.1093/infdis/130.2.112 · Cited by 71 · see citing works

Pharmacodynamics of echinocandins against Candida glabrata: requirement for dosage escalation to achieve maximal antifungal activity in neutropenic hosts

Howard, S. J., Livermore, J., Sharp, A., Goodwin, J., Gregson, L., Alastruey-Izquierdo, A., Perlin, D. S., Warn, P. A., & Hope, W. W. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00621-11 · Cited by 48 · see citing works

Natural insertions in rice commonly form tandem duplications indicative of patch-mediated double-strand break induction and repair

Vaughn, J. N., & Bennetzen, J. L. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1321854111 · Cited by 34 · see citing works

C. albicans resistance to 5-fluorocytosine.

Logan, R. L., & Goldberg, M. (1972) · BMJ · doi:10.1136/bmj.3.5825.531 · Cited by 9 · see citing works

Amphotericin B and flucytosine in the treatment of candidal cystitis.

Paladino, J. A., & Crass, R. E. (1983) · PubMed · Cited by 8 · see citing works

Multidrug-Resistant Candida: Epidemiology, Molecular Mechanisms, and Treatment

Arendrup, M. C., & Patterson, T. F. (2017) · The Journal of Infectious Diseases · doi:10.1093/infdis/jix131 · Cited by 707 · see citing works

Evolutionary Emergence of Drug Resistance in Candida Opportunistic Pathogens

Ksiezopolska, E., & Gabaldón, T. (2018) · Genes · doi:10.3390/genes9090461 · Cited by 230 · see citing works

Candida auris Pan-Drug-Resistant to Four Classes of Antifungal Agents

Jacobs, S. E., Jacobs, J. L., Dennis, E. K., Taimur, S., Rana, M., Patel, D., Gitman, M., Patel, G., Schaefer, S., Iyer, K., et al. (2022) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00053-22 · Cited by 190 · see citing works

Targeting Efflux Pumps to Overcome Antifungal Drug Resistance

Holmes, A. R., Cardno, T. S., Strouse, J. J., Ivnitski-Steele, I., Keniya, M. V., Lackovic, K., Monk, B. C., Sklar, L. A., & Cannon, R. D. (2016) · Future Medicinal Chemistry · doi:10.4155/fmc-2016-0050 · Cited by 156 · see citing works

Antifungal Resistance in Candida auris: Molecular Determinants

Frías-De-León, M. G., Hernández-Castro, R., Vite-Garín, T., Arenas, R., Bonifaz, A., Castañón-Olivares, L., Acosta-Altamirano, G., & Martínez-Herrera, E. (2020) · Antibiotics · doi:10.3390/antibiotics9090568 · Cited by 93 · see citing works

Facilitators of adaptation and antifungal resistance mechanisms in clinically relevant fungi

Hokken, M., Zwaan, B. J., Melchers, W. J. G., & Verweij, P. E. (2019) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2019.103254 · Cited by 94 · see citing works

Antifungal Combinations against Candida Species: From Bench to Bedside

Fioriti, S., Brescini, L., Pallotta, F., Canovari, B., Morroni, G., & Barchiesi, F. (2022) · Journal of Fungi · doi:10.3390/jof8101077 · Cited by 63 · see citing works

The yeast, the antifungal, and the wardrobe: a journey into antifungal resistance mechanisms of Candida tropicalis

de Oliveira, J. S., Pereira, V. S., Castelo‐Branco, D. D. S. C. M., Cordeiro, R. D. A., Sidrim, J. J. C., Brilhante, R. S. N., & Rocha, M. F. G. (2020) · Canadian Journal of Microbiology · doi:10.1139/cjm-2019-0531 · Cited by 38 · see citing works

Candida auris Urinary Tract Infections and Possible Treatment

Griffith, N. C., & Danziger, L. H. (2020) · Antibiotics · doi:10.3390/antibiotics9120898 · Cited by 38 · see citing works

A decade after the emergence of Candida auris: what do we know?

ElBaradei, A. (2020) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-020-03886-9 · Cited by 30 · see citing works

Species distribution and antifungal susceptibility patterns of Candida isolates from a public tertiary teaching hospital in the Eastern Cape Province, South Africa

Mnge, P., Okeleye, B. I., Vasaikar, S. D., & Apalata, T. R. (2017) · Brazilian Journal of Medical and Biological Research · doi:10.1590/1414-431x20175797 · Cited by 24 · see citing works

Mechanisms of Candida Resistance to Antimycotics and Promising Ways to Overcome It: The Role of Probiotics

Demin, K. A., Refeld, A. G., Bogdanova, A. A., Prazdnova, E. V., Popov, I. V., Kutsevalova, O. Y., Ermakov, A. M., Bren, A. B., Rudoy, D. V., Chistyakov, V. A., et al. (2021) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-021-09776-6 · Cited by 24 · see citing works

Research progress on the drug resistance mechanisms of Candida tropicalis and future solutions

Xiong, H., Zhao, R., Han, S., Liu, Z., Zhang, X., Jia, Z., Cui, J., Zhang, Y., & Wang, X. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1594226 · Cited by 22 · see citing works

The antifungal activity of caspofungin in combination with antifungals or non-antifungals against Candida species in vitro and in clinical therapy

Su, S., Yan, H., Li, M., Wang, H., Chen, X., Shi, J., & Sun, S. (2021) · Expert Review of Anti-infective Therapy · doi:10.1080/14787210.2021.1941868 · Cited by 22 · see citing works

A Review on Molecular Mechanisms of Antifungal Resistance in Candida glabrata : Update and Recent Advances

Lotfali, E., Fattahi, A., Sayyahfar, S., Ghasemi, R., Rabiei, M. M., Fathi, M., Vakili, K. G., Deravi, N., Soheili, A., Toreyhi, H., et al. (2021) · Microbial Drug Resistance · doi:10.1089/mdr.2020.0235 · Cited by 17 · see citing works

Cross-feeding affects the target of resistance evolution to an antifungal drug

Durand, R., Jalbert-Ross, J., Fijarczyk, A., Dubé, A. K., & Landry, C. R. (2023) · PLOS Genetics · doi:10.1371/journal.pgen.1011002 · Cited by 14 · see citing works

Advancements in nanoparticle-based therapies for multidrug-resistant candidiasis infections: a comprehensive review

Izadi, A., Paknia, F., Roostaee, M., Mousavi, S. A. A., & Barani, M. (2024) · Nanotechnology · doi:10.1088/1361-6528/ad4bed · Cited by 11 · see citing works

FungAMR: A comprehensive portrait of antimicrobial resistance mutations in fungiPreprint

Bédard, C., Pageau, A., Fijarczyk, A., Mendoza-Salido, D., Alcañiz, A. J., Després, P. C., Durand, R., Plante, S., Alexander, E. M. M., Rouleau, F. D., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.07.617009 · Cited by 9 · see citing works

Impact of Biofilm Formation by Vaginal Candida albicans and Candida glabrata Isolates and Their Antifungal Resistance: A Comprehensive Study in Ecuadorian Women

Cedeño-Pinargote, A. C., Jara-Medina, N. R., Pineda-Cabrera, C. C., Cueva, D. F., Erazo-Garcia, M. P., Tejera, E., & Machado, A. (2025) · Journal of Fungi · doi:10.3390/jof11090620 · Cited by 10 · see citing works

Natural Source-Derived Compounds with Antifungal Activity Against Medically Relevant Fungi

Gómez-Gaviria, M., Baruch-Martínez, D. A., & Mora-Montes, H. M. (2025) · Infection and Drug Resistance · doi:10.2147/idr.s554647 · Cited by 6 · see citing works

Investigation of Candida auris in Tanta University Hospitals, Egypt

Maxwell, S. Y., & Abd-Elmonsef, M. M. E. (2022) · The Egyptian Journal of Medical Microbiology · doi:10.21608/ejmm.2022.211980 · Cited by 6 · see citing works

Allylamines, Morpholine Derivatives, Fluoropyrimidines, and Griseofulvin

Ishida, K., & Barroso, V. D. M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-809633-8.21025-x · Cited by 3 · see citing works

Drug analysis of a fatal case of bloodstream infection combined with urinary tract infection due to echinocandin-resistant Candida glabrata

Wang, L., Wang, L., Liu, M., Ou, Y., Yang, L., & Chen, R. (2025) · IDCases · doi:10.1016/j.idcr.2025.e02261 · Cited by 2 · see citing works

Identification, antifungal resistance, and genomic characterization of a single Candida auris isolate from urinary tract infection

Li, J., Wang, Z., Zheng, R., Wang, Y., Guo, X., Li, X., & Zhang, P. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1641542 · Cited by 1 · see citing works

Actinic cystitis associated with urinary tract infection by Candida glabrata as a differential diagnosis of pudendal neuralgia. Case report

Hoffmann, L. Y., Daronco, A., & Seyboth, E. H. (2020) · Brazilian Journal Of Pain · doi:10.5935/2595-0118.20200032

Flucytosine

(2016) · Reactions Weekly · doi:10.1007/s40278-016-13888-5

Acquisition de résistance à la 5-fluorocytosine chez deux patients atteints de candidurie à Candida glabrata

Sissy, C. E., Charlier, C., Bachellier‐Bassi, S., Sitterlé, E., Quesne, G., Lortholary, O., & Bougnoux, M. (2015) · Journal de Mycologie Médicale · doi:10.1016/j.mycmed.2015.06.017

Failure of Caspofungin for Treatment of Candida glabrata Candiduria

Malani, A. N. (2010) · Infectious Diseases in Clinical Practice · doi:10.1097/ipc.0b013e3181d04a1d · Cited by 13 · see citing works

Outcomes of caspofungin use in the treatment of Candida-related urinary tract infections, a case series

Rkieh, L., Nekidy, W. S. E., Alsoud, L. O., Alatoom, A. A., Lababidi, R. E., Mooty, M., & Nusair, A. R. (2022) · IDCases · doi:10.1016/j.idcr.2022.e01510 · Cited by 9 · see citing works

A case of Candida glabrata severe urinary sepsis successfully treated with micafungin

Pieralli, F., Bazzini, C., Vannucchi, V., Mancini, A., & Nozzoli, C. (2014) · Medical Mycology Case Reports · doi:10.1016/j.mmcr.2014.04.003 · Cited by 16 · see citing works

Reduced <i>Candida glabrata</i> Susceptibility Secondary to an <i>FKS1</i> Mutation Developed during Candidemia Treatment

Cleary, J. D., Garcia-Effron, G., Chapman, S. W., & Perlin, D. S. (2008) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01568-07 · Cited by 118 · see citing works