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Antifungal Activity of Flocculosin, a Novel Glycolipid Isolated from Pseudozyma flocculosa
Open accessAbstract
Flocculosin, a glycolipid isolated from the yeast-like fungus Pseudozyma flocculosa , was investigated for in vitro antifungal activity. The compound displayed antifungal properties against several pathogenic yeasts. Synergistic activity was observed between flocculosin and amphotericin B, and no significant cytotoxicity was demonstrated when tested against human cell lines.
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Metadata
- Authors
- Mimee, B., Labbé, C., Pelletier, R., & Bélanger, R. R.
- Affiliations
- Université Laval (CA)
- Centre de Recherche en Horticulture, Université Laval
- Centre hospitalier universitaire de Québec (CA)
- ORCID
- Mimee, Benjamin
- Venue
- Antimicrobial Agents and Chemotherapy
- Publisher
- American Society for Microbiology
- Published
- 2005-04
- Volume
- 49
- Issue
- 4
- Pages
- 1597-1599
- ISSN
- 0066-4804 (ISSN-L)
- 1098-6596
- PMC
- PMC1068648
- OpenAlex
- W2069906206
- Cited by
- 102
- References
- 13
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 7 · 2023: 6 · 2022: 3 · 2021: 9 · 2019: 2 · 2018: 1 · 2017: 4 · 2016: 4 · 2015: 2 · 2014: 5 · 2013: 5 · 2012: 7
- FWCI
- 4.47
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Antimicrobial Agents and Chemotherapy (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Microbial Natural Products and Biosynthesis
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Infectious Diseases › Fungal Infections and Studies
- Keywords
- glycolipids, antifungal activity, pathogenic yeasts, synergistic activity, amphotericin B, cytotoxicity, yeast-like fungi
- MeSH terms
- Amphotericin B, Antifungal Agents, Cellobiose, Drug Synergism, Fungi, Glycolipids, Humans, Microbial Sensitivity Tests, Mycoses, Ustilaginales
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