The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Nanoparticles Functionalized with Ampicillin Destroy Multiple-Antibiotic-Resistant Isolates of Pseudomonas aeruginosa and Enterobacter aerogenes and Methicillin-Resistant Staphylococcus aureus
Open accessAbstract
We show here that silver nanoparticles (AgNP) were intrinsically antibacterial, whereas gold nanoparticles (AuNP) were antimicrobial only when ampicillin was bound to their surfaces. Both AuNP and AgNP functionalized with ampicillin were effective broad-spectrum bactericides against Gram-negative and Gram-positive bacteria. Most importantly, when AuNP and AgNP were functionalized with ampicillin they became potent bactericidal agents with unique properties that subverted antibiotic resistance mechanisms of multiple-drug-resistant bacteria.
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Hidron, A. I., Edwards, J. R., Patel, J., Horan, T. C., Sievert, D. M., Pollock, D. A., Fridkin, S. K., & National Healthcare Safety Network Team and Participating National Healthcare Safety Network Facilities (2008) · Infection Control & Hospital Epidemiology · doi:10.1086/591861 · Cited by 3,724
Cited by
Alternative Antimicrobial Approach: Nano-Antimicrobial Materials
Beyth, N., Houri-Haddad, Y., Domb, A., Khan, W., & Hazan, R. (2015) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2015/246012 · Cited by 837
Chandrakala, V., Aruna, V., & Angajala, G. (2022) · Emergent Materials · doi:10.1007/s42247-021-00335-x · Cited by 768
Azad, F. N., Ghaedi, M., Dashtian, K., Hajati, S., & Pezeshkpour, V. (2016) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2016.01.024 · Cited by 319
Mutuku, C., Gazdag, Z., & Melegh, S. (2022) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-022-03334-0 · Cited by 280
Shaaban, M. I., Shaker, M. A., & Mady, F. M. (2017) · Journal of Nanobiotechnology · doi:10.1186/s12951-017-0262-9 · Cited by 58
Metadata
- Authors
- Brown, A. N., Smith, K., Samuels, T. A., Lu, J., Obare, S. O., & Scott, M. E.
- Venue
- Applied and Environmental Microbiology
- Publisher
- American Society for Microbiology
- Published
- 2012-04-15
- Volume
- 78
- Issue
- 8
- Pages
- 2768-2774
- ISSN
- 0099-2240 (ISSN-L)
- 1098-5336
- OpenAlex
- W2036916534
- Cited by
- 420
- References
- 1
- FWCI
- 6.08
- Type
- journal article
- Language
- en
- Open access
- green
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- The paper
- Brown, A. N., Smith, K., Samuels, T. A., Lu, J., Obare, S. O., & Scott, M. E. (2012). Nanoparticles Functionalized with Ampicillin Destroy Multiple-Antibiotic-Resistant Isolates of Pseudomonas aeruginosa and Enterobacter aerogenes and Methicillin-Resistant Staphylococcus aureus. Applied and Environmental Microbiology. https://doi.org/10.1128/aem.06513-11
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.