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Lactobacilli and bile salt hydrolase in the murine intestinal tract
Open accessAbstract
Mice that have a complex intestinal microflora but that do not harbor lactobacilli were used to determine the contribution of lactobacilli to the total bile salt hydrolase activity in the murine intestinal tract. Bile salt hydrolase activity in the ileal contents of these mice was reduced 86% in the absence of lactobacilli and by greater than 98% in the absence of lactobacilli and enterococci compared with samples from conventional mice. Bile salt hydrolase activities were lower in ileal and cecal contents from lactobacillus-free mice colonized with enterococci than in samples from lactobacillus-free mice colonized with lactobacilli. Bile salt hydrolase activity in the duodena, jejuna, ilea, and ceca of reconstituted lactobacillus-free mice colonized by lactobacilli was similar to that in samples from the intestinal tracts of conventional mice. We conclude from these studies that lactobacilli are the main contributors to total bile salt hydrolase activity in the murine intestinal tract.
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Cites
THE FECAL FLORA OF VARIOUS STRAINS OF MICE. ITS BEARING ON THEIR SUSCEPTIBILITY TO ENDOTOXIN
Schaedler, R. W., & Dubos, R. J. (1962) · The Journal of Experimental Medicine · doi:10.1084/jem.115.6.1149 · Cited by 143
Cited by
Bile salt biotransformations by human intestinal bacteria
Ridlon, J. M., Kang, D.-J., & Hylemon, P. B. (2006) · Journal of Lipid Research · doi:10.1194/jlr.r500013-jlr200 · Cited by 2,829
Bile Salt Hydrolase Activity in Probiotics
Begley, M., Hill, C., & Gahan, C. G. M. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.72.3.1729-1738.2006 · Cited by 1,187
Huang, F., Zheng, X., Ma, X., Jiang, R., Zhou, W., Zhou, S., Zhang, Y., Lei, S., Wang, S., Kuang, J., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12896-x · Cited by 789
Probiotics: determinants of survival and growth in the gut
Bezkorovainy, A. (2001) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/73.2.399s · Cited by 533
Interactions between gut bacteria and bile in health and disease
Long, S. L., Gahan, C. G. M., & Joyce, S. A. (2017) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2017.06.002 · Cited by 495
Metadata
- Authors
- Tannock, G. W., Dashkevicz, M. P., & Feighner, S. D.
- Venue
- Applied and Environmental Microbiology
- Publisher
- American Society for Microbiology
- Published
- 1989-07
- Volume
- 55
- Issue
- 7
- Pages
- 1848-1851
- ISSN
- 0099-2240 (ISSN-L)
- 1098-5336
- OpenAlex
- W1592794451
- Cited by
- 166
- References
- 1
- FWCI
- 1.86
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Tannock, G. W., Dashkevicz, M. P., & Feighner, S. D. (1989). Lactobacilli and bile salt hydrolase in the murine intestinal tract. Applied and Environmental Microbiology. https://doi.org/10.1128/aem.55.7.1848-1851.1989
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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