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Cited by 274

The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.

Isolation and Characterization of Novel Marine-Derived Actinomycete Taxa Rich in Bioactive Metabolites

Open access
Magarvey, Nathan A., Keller, Jessica M., Bernan, Valerie, Dworkin, Martin, Sherman, David H.·2004·Applied and Environmental Microbiology

Abstract

A unique selective enrichment procedure has resulted in the isolation and identification of two new genera of marine-derived actinobacteria. Approximately 90% of the microorganisms cultured by using the presented method were from the prospective new genera, a result indicative of its high selectivity. In this study, 102 actinomycetes were isolated from subtidal marine sediments collected from the Bismarck Sea and the Solomon Sea off the coast of Papua New Guinea. A combination of physiological parameters, chemotaxonomic characteristics, distinguishing 16S rRNA gene sequences, and phylogenetic analysis based on 16S rRNA genes provided strong evidence for the two new genera (represented by strains of the PNG1 clade and strain UMM518) within the family Micromonosporaceae . Biological activity testing of fermentation products from the new marine-derived actinomycetes revealed that several had activities against multidrug-resistant gram-positive pathogens, malignant cells, and vaccinia virus replication.

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Crossref · 10.1128/aem.70.12.7520-7529.2004

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Metadata

Authors
Magarvey, N. A., Keller, J. M., Bernan, V., Dworkin, M., & Sherman, D. H.
Venue
Applied and Environmental Microbiology
Published
2004-12
Volume
70
Issue
12
Pages
7520-7529
ISSN
  • 0099-2240 (ISSN-L)
  • 1098-5336
OpenAlex
W1970935314
Cited by
274
References
27
FWCI
4.89
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Isolation and Characterization of Novel Marine-Derived Actinomycete Taxa Rich in Bioactive Metabolites. https://app.cochat.ai/papers/10.1128/aem.70.12.7520-7529.2004
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Magarvey, N. A., Keller, J. M., Bernan, V., Dworkin, M., & Sherman, D. H. (2004). Isolation and Characterization of Novel Marine-Derived Actinomycete Taxa Rich in Bioactive Metabolites. Applied and Environmental Microbiology. https://doi.org/10.1128/aem.70.12.7520-7529.2004

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.