Monitoring specific T-cell responses to melanoma vaccines: ELISPOT, tetramers, and beyond

Phenotypic Analysis of Antigen-Specific T Lymphocytes

Altman, J. D., Moss, P. A. H., Goulder, P. J. R., Barouch, D. H., McHeyzer-Williams, M. G., Bell, J. I., McMichael, A. J., & Davis, M. M. (1996) · Science · doi:10.1126/science.274.5284.94 · Cited by 3,544 · cited 15× · see citing works

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

Nestle, F. O., Alijagic, S., Gilliet, M., Sun, Y., Grabbe, S., Dummer, R., Burg, G., & Schadendorf, D. (1998) · Nature Medicine · doi:10.1038/nm0398-328 · Cited by 2,862 · see citing works

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

Rosenberg, S. A., Yang, J. C., Schwartzentruber, D. J., Hwu, P., Marincola, F. M., Topalian, S. L., Restifo, N. P., Dudley, M. E., Schwarz, S. L., Spiess, P. J., et al. (1998) · Nature Medicine · doi:10.1038/nm0398-321 · Cited by 1,786 · see citing works

Tumor Antigens Recognized by T Lymphocytes

Boon, T., Cerottini, J. C., den Eynde, B. J. V., van der Bruggen, P., & Pel, A. V. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.002005 · Cited by 1,228 · see citing works

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

Lee, P. P., Yee, C., Savage, P. A., Fong, L. H., Brockstedt, D. G., Weber, J. S., Johnson, D. L., Swetter, S. M., Thompson, J. A., Greenberg, P. D., et al. (1999) · Nature Medicine · doi:10.1038/9525 · Cited by 1,117 · see citing works

Phenotypic analysis of antigen-specific T lymphocytes. Science. 1996. 274: 94-96.

Altman, J. D., Moss, P. A. H., Goulder, P., Barouch, D. H., McHeyzer‐Williams, M. G., Bell, J. I., McMichael, A. J., & Davis, M. M. (2011) · PubMed · Cited by 572 · see citing works

High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals

Pittet, M. J., Valmori, D., Dunbar, P. R., Speiser, D. E., Líénard, D., Lejeune, F. J., Fleischhauer, K., Cerundolo, V., Cerottini, J., & Romero, P. J. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.190.5.705 · Cited by 508 · see citing works

Enhancement of cellular immunity in melanoma patients immunized with a peptide from MART-1/Melan A.

Cormier, J. N., Salgaller, M. L., Prevette, T., Barracchini, K. C., Rivoltini, L., Restifo, N. P., Rosenberg, S. A., & Marincola, F. M. (1997) · PubMed · Cited by 277 · see citing works

Melanoma-specific CD4+ T cells recognize nonmutated HLA-DR-restricted tyrosinase epitopes.

Topalian, S. L., Gonzales, M. I., Parkhurst, M. R., Li, Y. F., Southwood, S., Sette, A., Rosenberg, S. A., & Robbins, P. F. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.183.5.1965 · Cited by 257 · see citing works

Direct visualization of antigen-specific T cells: HTLV-1 Tax11–19- specific CD8 + T cells are activated in peripheral blood and accumulate in cerebrospinal fluid from HAM/TSP patients

Greten, T. F., Slansky, J. E., Kubota, R., Soldan, S. S., Jaffee, E. M., Leist, T. P., Pardoll, D. M., Jacobson, S., & Schneck, J. P. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.13.7568 · Cited by 247 · see citing works

An Expanded Peripheral T Cell Population to a Cytotoxic T Lymphocyte (Ctl)-Defined, Melanocyte-Specific Antigen in Metastatic Melanoma Patients Impacts on Generation of Peptide-Specific Ctls but Does Not Overcome Tumor Escape from Immune Surveillance in Metastatic Lesions

Anichini, A., Molla, A., Mortarini, R., Tragni, G., Bersani, I., Nicola, M. D., Gianni, A. M., Pilotti, S., Dunbar, P. R., Cerundolo, V., et al. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.190.5.651 · Cited by 190 · see citing works

Precursor frequency analysis of human cytolytic T lymphocytes directed against autologous melanoma cells

Coulie, P. G., Somville, M., Lehmann, F. F., Hainaut, P., Brasseur, F., Devos, R., & Boon, T. (1992) · International Journal of Cancer · doi:10.1002/ijc.2910500220 · Cited by 130 · see citing works

CDK4 gene amplification in osteosarcoma: Reciprocal relationship withINK4A gene alterations and mapping of 12q13 amplicons

Guo, W., Lonardo, F., Ueda, T., Kim, T. K., Huvos, A. G., Healey, J. H., & Ladanyi, M. (1999) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19990118)80:2 · Cited by 120 · see citing works

Evaluation of the Modified ELISPOT Assay for Gamma Interferon Production in Cancer Patients Receiving Antitumor Vaccines

Asai, T., Storkus, W. J., & Whiteside, T. L. (2000) · Clinical and Diagnostic Laboratory Immunology · doi:10.1128/cdli.7.2.145-154.2000 · Cited by 99 · see citing works

THE IMMUNOTHERAPY OF SOLID CANCERS BASED ON CLONING THE GENES ENCODING TUMOR-REJECTION ANTIGENS

Rosenberg, S. A. (1996) · Annual Review of Medicine · doi:10.1146/annurev.med.47.1.481 · Cited by 87 · see citing works

Diet and nasopharyngeal cancer in a low-risk population

Farrow, D. C., Vaughan, T. L., Berwick, M., Lynch, C. F., Swanson, G. M., & Lyon, J. L. (1998) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19981209)78:6 · Cited by 79 · see citing works

MHC-based diagnostics and therapeutics – clinical applications for disease-linked genes

Howard, M., Spack, E. G., Choudhury, K., Greten, T. F., & Schneck, J. P. (1999) · Immunology Today · doi:10.1016/s0167-5699(98)01390-5 · Cited by 36 · see citing works

Alterations in Signal Transduction in T Cells from Cancer Patients

Zea, A. H., Longo, D. L., Finke, J. H., Bukowski, R. M., & Ochoa, A. C. (1995) · Springer eBooks · doi:10.1007/978-1-4612-2536-2_7 · Cited by 33 · see citing works

Rational development of tumour antigen-specific immunization in melanoma.

Tf, G., & Fallarino, F. (1995) · PubMed · Cited by 11 · see citing works

Spontaneous T cell responses to melanoma differentiation antigens from melanoma patients and healthy subjects

Chen, Q., Jackson, H. M., Gibbs, P., Davis, I. D., Trapani, J. A., & Cebon, J. S. (1998) · Cancer Immunology Immunotherapy · doi:10.1007/s002620050520 · Cited by 10 · see citing works

Guidelines for the welfare and use of animals in cancer research

Workman, P., Aboagye, E. O., Balkwill, F. R., Balmain, A., Bruder, G., Chaplin, D. J., Double, J. A., Everitt, J. I., Farningham, D. A. H., Glennie, M. J., et al. (2010) · British Journal of Cancer · doi:10.1038/sj.bjc.6605642 · Cited by 1,450 · see citing works

The Next Hurdle in Cancer Immunotherapy: Overcoming the Non–T-Cell–Inflamed Tumor Microenvironment

Gajewski, T. F. (2015) · Seminars in Oncology · doi:10.1053/j.seminoncol.2015.05.011 · Cited by 485 · see citing works

Reimagining IDO Pathway Inhibition in Cancer Immunotherapy via Downstream Focus on the Tryptophan–Kynurenine–Aryl Hydrocarbon Axis

Labadie, B. W., Bao, R., & Luke, J. J. (2019) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-18-2882 · Cited by 413 · see citing works

Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression.

Geiger, J. D., Hutchinson, R. J., Hohenkirk, L., McKenna, E. A., Yanik, G. A., Levine, J. E., Chang, A. E., Braun, T., & Mulé, J. J. (2001) · PubMed · Cited by 320 · see citing works

Immunologic Monitoring of Cancer Vaccine Therapy: Results of a Workshop Sponsored by the Society for Biological Therapy

Keilholz, U., Weber, J. S., Finke, J. H., Gabrilovich, D. I., Kast, W. M., Disis, M. L., Kirkwood, J. M., Scheibenbogen, C., Schlom, J., Maino, V. C., et al. (2002) · Journal of Immunotherapy · doi:10.1097/00002371-200203000-00001 · Cited by 297 · see citing works

A phase I trial of tumor lysate-pulsed dendritic cells in the treatment of advanced cancer.

Chang, A. E., Redman, B. G., Whitfield, J. R., Nickoloff, B. J., Braun, T. M., Lee, P. P., Geiger, J. D., & Mulé, J. J. (2002) · PubMed · Cited by 222 · see citing works

Intensity of the Vaccine-Elicited Immune Response Determines Tumor Clearance

Pérez‐Díez, A., Spiess, P. J., Restifo, N. P., Matzinger, P., & Marincola, F. M. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.1.338 · Cited by 81 · see citing works

Reevaluation of the cellular immune response in breast cancer patients vaccinated with MUC1

Musselli, C., Ragupathi, G., Gilewski, T. A., Panageas, K. S., Spinat, Y., & Livingston, P. O. (2001) · International Journal of Cancer · doi:10.1002/ijc.10081 · Cited by 77 · see citing works

Frequency of MART-1/MelanA and gp100/PMel17-Specific T Cells in Tumor Metastases and Cultured Tumor-Infiltrating Lymphocytes

Seiter, S., Monsurrò, V., Nielsen, M.-B., Wang, E., Provenzano, M., Wunderlich, J. R., Rosenberg, S. A., & Marincola, F. M. (2002) · Journal of Immunotherapy · doi:10.1097/00002371-200205000-00008 · Cited by 45 · see citing works

Cancer vaccine development: on the way to break immune tolerance to malignant cells

D, S. M. M., Rossi, C. R., & Nitti, D. (2004) · Experimental Cell Research · doi:10.1016/j.yexcr.2004.06.017 · Cited by 35 · see citing works

MONITORING IMMUNE RESPONSES IN CANCER PATIENTS RECEIVING TUMOR VACCINES

Walker, E., & Disis, M. L. (2003) · International Reviews of Immunology · doi:10.1080/08830180305226 · Cited by 30 · see citing works

MHC class II tetramer analyses in AE37-vaccinated prostate cancer patients reveal vaccine-specific polyfunctional and long-lasting CD4+T-cells

Anastasopoulou, E. A., Voutsas, I. F., Papamichail, M., Baxevanis, C. N., & Perez, S. A. (2016) · OncoImmunology · doi:10.1080/2162402x.2016.1178439 · Cited by 17 · see citing works

Direct detection of cellular immune responses to cancer vaccines

Mosca, P. J., Hobeika, A. C., Clay, T. M., Morse, M. A., & Lyerly, H. K. (2001) · Surgery · doi:10.1067/msy.2001.108609 · Cited by 11 · see citing works

Clinical approaches to vaccination in oncology

Renner, C., Kubuschok, B., Trümper, L. H. P., & Pfreundschuh, M. G. (2001) · Annals of Hematology · doi:10.1007/s002770100324 · Cited by 10 · see citing works

Ex vivo detection of CD8 T cells specific for H-Y minor histocompatibility antigens in allogeneic hematopoietic stem cell transplant recipients

Nakamura, R., Rosa, C. L., Tsai, W., Lacey, S. F., Srivastava, T., Seidel, A., Senitzer, D., Forman, S. J., & Diamond, D. J. (2014) · Transplant Immunology · doi:10.1016/j.trim.2014.02.001 · Cited by 5 · see citing works

Gene Therapy for Antitumor Vaccination

Kim‐Schulze, S., & Kaufman, H. L. (2009) · Methods in molecular biology · doi:10.1007/978-1-59745-561-9_27 · Cited by 5 · see citing works

The T cell receptor repertoire reflects the dynamics of the immune response to vaccinationPreprint

Mohammed, K., Meadows, A., Hekmaty, S., Hatem, S., Simon, V. R., Jayaprakash, A. D., & Sachidanandam, R. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.09.471735 · Cited by 2 · see citing works

Peptide/MHC Tetramer Analysis

Lee, P. P., & Marincola, F. M. (2005) · Springer eBooks · doi:10.1007/1-4020-3623-x_11

Apport de la détection de l’activité des lymphocytes T cytotoxiques dirigés contre l’antigène Mélan-A/Mart-1 dans la chirurgie du mélanome malin cutané. Étude préliminaire

Chevrier, S., Drénou, B., Adamski, H., Aillet, S., & Watier, É. (2003) · Annales de Chirurgie Plastique Esthétique · doi:10.1016/s0294-1260(03)00040-2

MHC Tetramers

Chang, J. C. C., Kos, F. J., Nugent, C. T., & Kuus-Reichel, K. (2004) · Humana Press eBooks · doi:10.1007/978-1-59259-791-8_10

Tetramer Analysis

Lee, P. P. (2005) · Elsevier eBooks · doi:10.1016/b978-012455900-4/50284-1

T cell response to tumor antigens and its therapeutic use in cancer patients

Parmiani, G., Castelli, C., Dalerba, P. D., & Rivoltini, L. (2001) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-0685-0_59 · Cited by 2 · see citing works

Immunological monitoring: Lessons from natural and vaccine-induced responses to Melan-A/MART-1

Cerottini, J. (2003) · Cancer immunity

Use of major histocompatibility complex class I tetramers to monitor tumor-specific cytotoxic T lymphocyte response in melanoma patients

Cerundolo, V. (2000) · Cancer Chemotherapy and Pharmacology · doi:10.1007/pl00014056 · Cited by 7 · see citing works

Humoral immune response against melanoma antigens induced by vaccination with cytokine gene‐modified autologous tumor cells

Ehlken, H., Schadendorf, D., & Eichmüller, S. B. (2003) · International Journal of Cancer · doi:10.1002/ijc.11537 · Cited by 26 · see citing works

Genes coding for melanoma antigens recognised by cytolytic T lymphocytes

Smet, C. D., Lurquin, C., Plaen, E. D., Brasseur, F., Zarour, H. M., Backer, O. D., Coulie, P. G., & Boon, T. (1997) · Eye · doi:10.1038/eye.1997.59 · Cited by 19 · see citing works